Sentences with phrase «generate specific cell types»
This finding suggests their approach could be tailored to generate specific cell types for patients with different types of hypopituitarism.
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Zygotes generate specific types of cells in an orderly progression.
An APC - mimetic scaffold that was engineered to activate a specific type of CAR - T cell was able to generate higher numbers of the modified T cells over longer periods of culture than analogously designed expansion beads, and the resulting cells were similarly effective in killing the lymphoma cells in the mice.
«Our research revealed how small RNA molecules can work with other cell signals called transcription factors to generate specific types of neurons, in this case motor neurons.
«In the future, this will move us towards a way to understand how to generate a cardiac muscle or other specific cell type without having to try an unwieldy number of cell culture conditions.»
Pluripotent cells such as embryonic stem (ES) and induced pluripotent stem (iPS) cells are the starting point from which to generate organ specific cell types.
As an extension to genetics projects, we now aim to identify and characterize in greater depth genes implicated in hematopoietic development in the EU FP7 - funded BLUEPRINT project, which will generate reference genomes and epigenomes of at least 100 specific blood cell types.
Ultimately, we use all this information to establish innovative culture techniques for generating unlimited neural stem cell sources for the derivation of specific types of clinically relevant neuronal or glial cells, for their use in disease modelling and drug discovery platforms, and towards refining their efficacy for future cell replacement - based therapy.
Our objective is to generate a resource that facilitates research into human immune - related diseases by creating a comprehensive database of cell type - and allele - specific epigenomic and transcriptomic data for the immunology community.
Other cells are multipotent, meaning they can generate a few different cell types, generally in a specific tissue or organ.
We use the Cre - loxP recombination system to generate mice with cell type - specific inactivation of the IL - 10 gene in order to identify cellular sources of the cytokine that are relevant in various situations of immune challenge.
Since joining Gladstone, McDevitt's lab has created a new method to generate three - dimensional clusters of specific types of cells that can be used to form and maintain tissue constructs.
We have generated new genetic tools for the analysis of in vivo mast cell functions that allow for cell type - specific inactivation («knock out «-RRB- of target genes selectively in mast cells by Cre loxP - mediated recombination.