Sentences with phrase «generate stem cell lines»

Not exact matches

CMRB has two parts: the Cell Line Bank of Barcelona, which generates and maintains embryonic stem cell lines, and the CMRB research centre, which carries out basic and applied research to design future strategies for regenerative medicCell Line Bank of Barcelona, which generates and maintains embryonic stem cell lines, and the CMRB research centre, which carries out basic and applied research to design future strategies for regenerative mediccell lines, and the CMRB research centre, which carries out basic and applied research to design future strategies for regenerative medicine.

A stem cell core facility at CHOP, directed by study co-author Deborah French under the auspices of the hospital's Center for Cellular and Molecular Therapeutics, generated the iPSCs lines used in these studies.

In one promising approach, cellular reprogramming, stem cells can be generated by fusing adult skin cells with embryonic stem cells from existing cell lines.

Intestinal stem cells are particularly important because a new intestinal lining is generated about every 4 - 5 days.

In a paper published online yesterday in Stem Cells, the researchers report that they succeeded in generating pluripotent human ES cell lines — i.e., cells that can develop into many different kinds of cells — from one of the 13 late - arrested embCells, the researchers report that they succeeded in generating pluripotent human ES cell lines — i.e., cells that can develop into many different kinds of cells — from one of the 13 late - arrested embcells that can develop into many different kinds of cells — from one of the 13 late - arrested embcells — from one of the 13 late - arrested embryos.

The finding potentially paves the way for scores of labs to generate new stem cell lines without cloned embryos, which had long been considered the only realistic way of making human stem cells in the short run.

Alternative cell lines, such as induced pluripotent stem cells generated from patient skin cells, offer a more accurate window on human biology, he says.

Australian researchers have so far generated over 50 embryonic stem cell lines from surplus embryos, and three research groups have been licensed to attempt somatic cell nuclear transfer.

Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory - generated stem cells comes to mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells.

«The [stem cell] lines we generated are the real thing.

«It conclusively proves that the stem cell line in question was not cloned as claimed, but rather was generated through parthenogenesis.»

These stem cells live in the lining of the intestine, known as the epithelium, and generate all of the different cell types that make up the epithelium.

NeuroStemcell is focused on the identification and systematic comparison of progenitor cell lines with the most favourable characteristics for mesDA and striatal GABAergic neuronal differentiation, generated either directly from human embryonic stem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals modstem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals modStem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals modStem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals models.

The Repository of mouse ES cell lines, strains and vectors generated by the trans - NIH KOMP initiative that aims to generate a public resource comprised of mouse embryonic stem (ES) cells containing a null mutation in every gene in the mouse genome.

One important line of our work has revealed mechanisms how hematopoietic stem cells can generate more myeloid cells to protect transplant recipients from lethal infections.

The team that generated the insulin - producing embryonic stem cell line, e.g., had a success rate of under six percent, using 71 eggs to produce four stem cell lines from the embryos they created and destroyed.

One of those teams created a cloned embryo from the somatic cells of a diabetic patient; this embryo was then destroyed in order to generate an insulin - producing embryonic stem cell line.

Embryonic cell lines and autologous embryonic stem cells generated through therapeutic cloning have also been proposed as promising candidates for future therapies.

Citation: Li C, Yu H, Ma Y, Shi G, Jiang J, Gu J, et al. (2009) Germline - Competent Mouse - Induced Pluripotent Stem Cell Lines Generated on Human Fibroblasts without Exogenous Leukemia Inhibitory Factor.

Embryonic stem (ES) cells are karyotypically normal, embryo - derived cell lines that are pluripotent, i.e. capable of generating all the cell types of the future organism, but not the extra-embryonic lineages.

A team led by Young - sup Yoon, MD, PhD developed a new method for generating endothelial cells, which make up the lining of blood vessels, from human induced pluripotent stem cells..

To further maximize accuracy, the researchers recommend that future studies involving stem cells use cell lines from as many individuals as possible rather than generating multiple cell lines from the same individual.

His pioneering mouse embryonic stem (ES) cell work in the 1980s, demonstrating germ - line transmission and the great potential of ES cells to generate mice carrying mutations in endogenous genes, established milestones in a field that saw the award of the 2007 Nobel Prize in Physiology or Medicine to Mario Capecchi, Martin Evans, and Oliver Smithies.

This induced pluripotent stem cell (iPSC) line was generated from IMR90 fetal lung fibroblasts by viral transduction of a combination of OCT4, SOX2, NANOG, and LIN28 genes.