Sentences with phrase «generate substantial marketing»

A drug with similar effects might generate substantial marketing... The very high heterogeneity... of effects among trials in the accompanying study highlights a research opportunity — to identify how to maximise the effect.»

Not exact matches

Prior to founding Orcam, Mr. Roche ran a private investment partnership in which he generated substantial alpha (high risk adjusted returns) with no negative 12 month periods during one of the most turbulent periods in stock market history.

This «generated substantial revenues for Wells Fargo» and provided «critical seed money that kept the funds afloat by boosting market share,» the complaint said.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

While growth stocks are those that are anticipated to generate substantial capital gains, value stocks are those that the market sees as underrated or ignored.

It is generating substantial operating cash flow and earnings, which in a better market might be worth more, but it's not obviously cheap to us.

We begin the process by focusing on companies that dominate their markets and demonstrate an ability to generate substantial free cash flow.

Highly Targeted Websites that dominate the market and generate a substantial amount of new client leads.

If you are not, you are passing up the substantial business that is generated through internet marketing.

First, in today's market a new REIT will likely generate substantial interest from equity investors, creating opportunity for equity and debt offerings.