Not exact matches
The numbers of
cells and proteins
generated by the
immune system of some SIDS babies have been reported to be higher than normal.
A final series of tests confirmed that toxic compounds
generated by antibodies kill bacteria without any help from other
immune cells, like macrophages.
The going theory for this — that antibodies
generated by a first bout with dengue bind to a second strain, which helps it multiply in the
immune cells — doesn't account for the internal bleeding and tissue damage, says Juthathip Mongkolsapaya of Mahidol University in Bangkok, Thailand.
Now an international team of biologists may have found a reason why: a signal
generated by the body's
immune cells renders the drugs useless.
The HZI will develop a vaccination protocol for mucosal administration based on three novel strategies: (i) development and optimization of a vaccination protocol in which parenterally - primed T and B
cells are subsequently pulled into the mucosa
by the local delivery of the cognate antigen to the requested effector site, (ii) testing the co-administration of antigens with novel mucosal adjuvants using different mucosal immunisation routes and schedules, and (iii) testing various nanoparticles co-administered with different immunomodulators for their ability to
generate both systemic and mucosal
immune responses following transcutaneous / trans - follicular vaccination.
The awards span the broad mission of the NIH and include groundbreaking research, such as engineering
immune cells producing drugs at the site of diseased tissue; developing a sensor to rapidly detect antibiotic resistance of a bacterial infection; understanding how certain parasites evade host detection
by continually changing their surface proteins; and developing implants that run off the electricity
generated from the motion of a beating the heart.
Interleukin - 21 (IL - 21): Delivering higher levels of IL - 21 has been demonstrated to improve the state of the
immune system
by increasing the pace at which new
immune cells are
generated.
By decreasing risk factors and harnessing the power of the human
immune system, inflammation can be decreased, new
cells can be
generated and the body can function better.
The lab is characterizing the quantity and quality (i.e. B and T
cell) of the
immune responses induced or
generated by these DNA plasmids in order to improve their ability to mediate virus neutralization and clearance.
«Having a very efficient and practical way of
generating patient - specific stem
cells, which unlike human embryonic stem
cells, wouldn't be rejected
by the patient's
immune system after transplantation brings us a step closer to the clinical application of stem
cell therapy,» says Belmonte, PhD., a professor in the Gene Expression Laboratory and director of the Center of Regenerative Medicine in Barcelona, Spain.
Our objective is to
generate a resource that facilitates research into human
immune - related diseases
by creating a comprehensive database of
cell type - and allele - specific epigenomic and transcriptomic data for the immunology community.
A recent study led
by BSI member Professor Andrew Sewell from Cardiff University and published in the Journal of Clinical Investigation showed that a synthetic «mirror image» version of a protein belonging to the influenza A virus
generated strong
immune responses in human
cells and mice, with the mice also being protected when exposed to a strain of influenza A.
In preclinical research, tumor
cells lysed
by coxsackievirus A21 (CVA21), a naturally occurring «common cold» ICAM - 1 — targeted RNA virus, induced a secondary systemic host -
generated antitumor
immune response.
It is Dr. Chou's hope that,
by treating colon cancer stem
cells with DAC and then exposing them to
immune cells that have been primed to recognize NY - ESO - 1, he can
generate a targeted and durable
immune response against these
cells without harming healthy
cells.
Also, while ketones can replace glucose as a fuel, they can not glycosylate proteins, or
generate ROS in the manner needed
by immune cells.
Abdominal fat, in particular, contains proinflammatory cytokines — the chemicals released
by immune cells — and hormones secreted
by fat tissue, which can
generate and perpetuate chronic inflammation.