Sentences with phrase «generated knockin»
We generated knockin / knockout mice that expressed only open syntaxin - 1B.
http://science.sciencemag.org/
It is this application - the creation of sequence - specific knockins - for which the AAV approach is most well suited, since it routinely generates knockin efficiencies of 1 - 40 % with G418 - selected clones.
Not exact matches
To investigate the role of cleavage in vivo, we generated by gene targeting a Pkd1 knockin mouse (Pkd1 (V / V)-RRB- that expresses noncleavable PC1.