Finally, the team conducted extensive cell experiments to confirm the computer -
generated signaling pathway model.
Not exact matches
Neurons that handle lots of robust, well - synchronized
signals sprout more neurotransmitter -
generated terminals, and their connections with other neurons along the
signaling pathway grow stronger.
Understanding how this
signaling pathway functions would allow for development of strategies to protect crops against climatic change and to improve photosynthesis so as to
generate biofuels and other valuable products.
«We can now use the TEA to
generate a comprehensive map of hormonal biosynthesis and
signaling pathways encompassing all fruit tissues.»
It's been shown that actually for insulin to act on this receptor, it actually has to transiently inhibit PTPs in order to allow for a
signal to be
generated, but as soon as this
signal goes through, this
pathway is inhibited.
We show that subpopulations of human astrocytes,
generated by activation of different
signaling pathways in the same population of human glial precursor cells, have markedly different effects when transplanted into the injured spinal cord.
Specifically, we have
generated clusters of transcripts that behave the same way under the entire spectrum of the sixty - seven experimental conditions; we have assembled genes in groups according to their time of expression during successive days of ES cell differentiation; we have included expression profiles of specific gene classes such as transcription regulatory factors and Expressed Sequence Tags; transcripts have been arranged in «Expression Waves» and juxtaposed to genes with opposite or complementary expression patterns; we have designed search engines to display the expression profile of any transcript during ES cell differentiation; gene expression data have been organized in animated graphs of KEGG
signaling and metabolic
pathways; and finally, we have incorporated advanced functional annotations for individual genes or gene clusters of interest and links to microarray and genomic resources.
Signaling through the CXCR3 - mediated, MyD88 - dependent
pathway generates a Th1 - dominant, pro-inflammatory cytokine milieu that recruits mononuclear cells into the submucosa (Fasano, 2011).