Sentences with phrase «generates phenotypic»
Professor Segal's research has two major directions 1) Gene regulation — using quantitative and computational models to understand how DNA sequence variation among human individuals generates phenotypic diversity 2) Microbiome and Nutrition — understanding how the microbial composition of individuals affect their physiology and health.
http://syscol-project.eu/
Our findings show that sex can generate phenotypic and genotypic diversity de novo in the pathogenic yeast C. neoformans with implications for other eukaryotic microbes and pathogens, including other fungi and parasites that are common pathogens of humans.
Aneuploidy was also detected in progeny from a-α opposite - sex congenic mating; thus, both homothallic and heterothallic sexual reproduction can generate phenotypic diversity de novo.
Not exact matches
To test this hypothesis, we isolated progeny generated via selfing α - α unisexual reproduction and subjected them to phenotypic and genotypic analyses.
Among 90 isolates generated from the selfing of this α + SXI2a self - fertile strain, seven strains exhibited phenotypic changes compared to the parental strain (Figure S14).
It combines the capacity of generating genetically engineered mouse model on a large scale with a high - throughput and comprehensive phenotypic analysis of the animals.
The project will also benefit from the RD - Connect Genome - Phenome Analysis Platform developed at CNAG - CRG; in this case, it will be used to collate existing and newly generated genomic and phenotypic data.
From 2008 - 2010, he was supported by the CGGH to study phenotypic variation in the drug sensitivity of Plasmodium falciparum isolates collected Kilifi District, and to investigate genotype - phenotype associations using genome sequencing data generated on these isolates at the Wellcome Trust Sanger Institute.
The CNAG - CRG hosts the RD - Connect Genome - Phenome Analysis Platform (https://platform.rd-connect.eu), which will be used in SOLVE - RD to collate existing and newly generated genomic and phenotypic data.