Sentences with phrase «generating antibodies»

Non-responders have an immune defect that prevents them from generating any antibodies at all to the vaccine.

B cells swing into action when the body is under attack, generating antibodies and fine - tuning them to fight specific infections.

Unlike vaccines for many viruses, those for HIV may have to go beyond generating antibodies.

Because the virus is unable to infect the same person twice — thanks to the immune system generating antibodies to kill it — the epidemic reaches a stage where there are too few people left to infect for transmission to be sustained.

She can then generate antibodies that can cross the placenta and attack baby's blood cells, resulting in anemia.»

While they're essential for helping the body fend off attacks, if something goes awry, B - cells can generate antibodies that attack healthy tissues.

Infection with one serotype generates antibodies that may cross-react and enhance infection with other serotypes in a secondary infection.

We'll be able to look back in time and see, for instance, that this particular mom generated antibodies to this particular virus at the 17th week, and now her kid is autistic.»

These children generate antibodies to molecules on streptococcal bacteria, and the antibodies may mistakenly target the child's basal ganglia, a cluster of neurons in the brain that regulate movement, thought, and emotion.

The researchers homed in on this viral protein after they noticed that the pathogenic effects of dengue virus infection were blocked in mice that had generated antibodies to NS1.

Most traditional vaccines generate antibodies against the hemagglutinin head.

The findings highlight a novel way to generate antibodies that recognize and target proteins shared by most influenza A strains rather than those unique to each strain.

B lymphocytes generate the antibodies that protect us against infection by pathogens.

Hay's team also showed that the same approach could be used to make female mice generate antibodies to the zona pellucida, a layer of proteins that surrounds egg cells.

After receiving the injection, the body generates antibodies that respond to the cholera protein and the cocaine.

The new technology was tested in mice for the ability to generate antibodies in their blood stream that would target human PSMA as well as target PSMA - positive tumors.

Some people infected with HIV generate antibodies that fend off the virus successfully for decades.

Professor Hayday added: «This is very significant because antibodies make up one of the largest sectors of the pharmaceutical market, and one of the great quests in the pharmaceutical industry is to be able to routinely generate antibodies against human proteins implicated in diseases.

«An obstacle to creating an effective HIV vaccine is the difficulty of getting the immune system to generate antibodies against the sugar shield of multiple HIV strains,» said Lai - Xi Wang, a professor of chemistry and biochemistry at UMD.

Removing the cytoplasmic domain may distract the immune response and instead generate antibodies that target epitopes on Env that would not lead to protection.

In its first test in people, a vaccine against the toxin ricin appears safe and generates antibodies that are expected to be protective against the potential bioterrorism agent.

Rabbit monoclonals provide better antigen recognition because the rabbit immune system generates antibody diversity, and optimizes affinity by mechanisms that are more efficient than those of mice and other rodents.

In our experience, full - length fusion protein antigens usually generate antibodies with higher titers and higher sensitivities.

«These studies clearly show us that the vaccine is able to generate antibodies that protect the mice from Zika infection.

The RTM hypothesis is that the immune systems of people who reach the ages at which AS, beta - amyloid, and other pathological aggregates begin to accumulate would generate antibodies against their abnormal form, and that people who remain free of these specific diseases might be producing antibodies that are particularly effective at keeping these aggregates at bay.

In the RV144 trial, a subunit protein boost was similarly used to effectively generate antibodies.

At the International AIDS Society conference in Paris, scientists announced that in an early - stage clinical trial, a new HIV vaccine regimen generated antibody responses in 100 percent of volunteers in most arms of the study.

This is important: if the fetus had an ability to generate antibodies and mount an immune response, it might generate immune attacks against the mother leading to miscarriage.

Low LDL signifies a reduced ability to generate antibodies.

WGA can act as an adjuvant, causing the body to generate antibodies against proteins that, in isolation, the body would not form antibodies against.

This vaccine generates antibodies specifically against OspA, the surface protein the spirochete uses to attach to its tick host.

Any exposure no matter how small is likely to generate some antibodies.

The puppy's immune system then leaps into action and generates antibodies to fight that disease.

Not exact matches

«In the case of multiple sclerosis, as a patient progresses through steps of the disease, their body generates novel antibodies or higher existing antibody titers against certain proteins, such as myelination proteins.

In such patients, a phenomenon called «antibody - dependent enhancement» (ADE) takes place, during which antibodies that were generated during the first infection bind but do not destroy the slightly different newly infecting virus, but instead facilitate its infection of immune cells.

For example, some antibody manufacturers offer prizes for the best pictures generated using their products.

In a collaborative project with several project partners and funded by the European Union and the Deutsche Forschungsgemeinschaft novel Sclerostin - inhibiting antibodies were generated and analysed for their suitability as osteoporosis treatment option.

In a study published in the May 29, 2014, edition of Molecular Ecology Resources, Duke researchers Peter Larsen, Ryan Campbell and Anne Yoder used high - throughput sequencing on sifaka blood samples to generate sequence data for more than 150,000 different sifaka antibodies — protective molecules that latch on to bacteria, viruses and other foreign invaders in the body and fight them off before they cause infection.

The work identifies «a new and much more efficient method to generate broadly active antibodies against HIV,» says immunologist Justin Bailey of Johns Hopkins University School of Medicine, who was not involved in the study.

About 1 percent of HIV - infected people eventually generate broadly neutralizing antibodies that are especially potent and effective against many types of HIV.

These antibodies appeared to have been initially generated in response to an earlier infection by a related virus that causes dengue.

This one - two punch protected the test subjects against influenza A viruses that had emerged in 1934 and 2007, and other experiments showed that the antibodies it generated successfully neutralized a wide variety of flu strains.

Aguzzi and his team tested this by generating mimetic antibodies in tissue sections from the cerebellum of mice which have a similar toxicity to that of a prion infection.

But he cautions that follow - up studies are needed to prove whether the antibodies are really burning water to generate the reactive compounds.

A final series of tests confirmed that toxic compounds generated by antibodies kill bacteria without any help from other immune cells, like macrophages.

Oddly, the antibodies kept generating a reactive compound, hydrogen peroxide.

Maternal immunization is one way to help protect them because the antibodies that the mom generates in response to the vaccine can be passed to her unborn child.

She's also been unable to generate a good antibody to Abc1.

This study also advanced understanding of the role a protein named mTOR plays in generating the highly specific antibodies.

Teijaro adds that the ideal approach may be to combine the HIS virus vaccine with a strategy to generate broadly neutralizing antibodies — those that can bind many different influenza strains — to create a universal flu vaccine (SN: 10/28/17, p. 18).