Sentences with phrase «generation drug for»

A team led by Eric Klann and Moses Chao at New York University analyzed neurons in culture and in live mice to see what happened at the molecular level when neurons were exposed to haloperidol, a first - generation drug for schizophrenia.

Not exact matches

The ongoing American Heart Association (AHA) meeting in New Orleans is producing a deluge of data — including some promising prospects for a class of next - generation cholesterol drugs that have been slow to take off so far in the U.S. So - called PCSK9 inhibitors have shown tremendous efficacy in lowering LDL - C, or «bad» cholesterol.

Nor can every product be built for prices the average Joe is willing to risk (for example, the next Tesla automobile), or be brought to market for less than $ 10 million (e.g., the next generation of cholesterol drugs).

Bensinger, DuPont & Associates, a firm that provides employee drug testing and assistance for problems like gambling, published the survey, Depression and Work: The Impact of Depression on Different Generations of Employees, to coincide with National Mental Health Awareness Month.

RESEARCHERS at Curtin University have commenced a project to develop a new generation of drugs for treatment of HIV - AIDS, asthma and melanoma.

Sierra Oncology, Inc., a clinical stage drug development company focused on advancing next - generation DNA damage response therapeutics for the treatment of patients with cancer, went public near $ 29 in July 2015, then began a downtrend that continued through a June 2017 all - time low of $ 1.10.

New York, Wall Street Journal — Genomic Health Inc. has struck a deal to commercialize a new blood test that can help advanced prostate cancer patients decide whether to try costly new - generation drugs or rely on much cheaper traditional chemotherapy to improve their chances for survival.

Graham Lumsden, chief executive of Motif Bio Plc (LON: MTFB), caught up with Proactive's Andrew Scott as the drug developer gears up for the commercial launch of its next - generation antibiotic.

This perspective unmistakably reveals the unwholesomeness, not to put it more strongly, of our way of life: our obsession with sex, violence, and the pornography of «making it;» our addictive dependence on drugs, «entertainment,» and the evening news; our impatience with anything that limits our sovereign freedom of choice, especially with the constraints of marital and familial ties; our preference for «nonbinding commitments;» our third - rate educational system; our third - rate morality; our refusal to draw a distinction between right and wrong, lest we «impose» their morality on us; our reluctance to judge or be judged; our indifference to the needs of future generations, as evidence by our willingness to saddle them with a huge national debt, an overgrown arsenal of destruction, and a deteriorating environment; our unsated assumption, which underlies so much of the propaganda for unlimited abortion, that only those children born for success ought to be allowed to be born at all.

The sixties generation's inordinate self - regard; their demand to be given, without striving for it, all the goodies their society had to offer, including, of course, easy sex; their recourse to the instant and unearned sense of power and comfort supplied by drugs; their refusal to serve their country; their general ingratitude, expressed most of all in their declared intention to lead lives in no respect like those of their forebears — all these were translations of the hubris that, partly unconsciously but entirely influentially, constituted the basic underpinning of their upbringing.

Travis Tygart, president of the USADA, said in a statement, «This is a heartbreaking example of how the win - at - all - costs culture of sport, if left unchecked, will overtake fair, safe and honest competition, but for clean athletes, it is a reassuring reminder that there is hope for future generations to compete on a level playing field without the use of performance - enhancing drugs»...

This is arguably the most important moment in British drug policy for a generation.

(Posted 24 December 2011) Significant current scandals, and those yet to come In no particular order Top salaries and bonuses - boardroom and shareholder individual responsibility The multiple between top and average pay Lawyers fees - the cost of the legal process Medical negligence claims against the NHS Care and treatment in the NHS «No win, no fee» personal injury compensation Democracy and the voting system Lords reform Political party funding The domestic energy market and pricing The Tax system and its inefficiencies and complexities Subsidies for new energy generation schemes The amount of crime fuelled by Drugs The availability of drugs in prDrugs The availability of drugs in prdrugs in prison.

«This discovery opens the way for the rational design of a new generation of antipsychotic drugs, hopefully with more desirable effects and fewer side effects.»

Radioprotective Drugs; Modeling the Supergreenhouse; New Treatments for Alcoholism; Generation Y Workforce [MP3].

The study, called the Bypass Surgery Versus Everolimus - Eluting Stent Implantation for Multivessel Coronary Artery Disease (BEST) trial, is one of only two randomized controlled trials to compare bypass to angioplasty since the introduction of everolimus - eluting stents, a new generation of drug - eluting stent.

And is it fair for the wealthy to access a new generation of costly, off - label smart drugs while the rest of us do without?

When this article was first published, the number of generations for which the drug is effective was printed incorrectly.

This achievement will also contribute to accelerating the research applications of RNAi such as to the development of RNA - based next - generation drugs, for example as gene therapy to suppress the production of a disease - causing protein.

This room is a testing ground for new generations of drugs to treat women who have lost their zest for sex — and therefore, suggest researchers at the center, for life.

At New Scientist, he continued his campaigning and infected a younger generation of journalists with a strong scepticism for the inflated claims drugs companies made about their products.

The next generation drug in the taxane family, cabazitaxel, was approved in 2010, but only for patients whose cancer no longer responded to hormone therapy or docetaxel treatment.

An understanding of the genetics of weight control is helping researchers develop a new generation of drugs for weight control.

«Finding increased vulnerability to drug addiction and compulsive behavior in generations not directly exposed is an important consideration for legislators considering legalizing marijuana.»

The researchers tested two anti-CK2 drugs for their ability to stimulate the production of new brown fat in mice: a new small - molecule CK2 - blocker called silmitasertib (CX - 4945), which is already in clinical trials as a cancer therapeutic; and a more precise next - generation antisense oligonucleotide (ASO) drug developed in collaboration with Isis Pharmaceuticals, which eliminates CK2 by blocking the RNA instructions cells use to produce it.

In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time designed a drug candidate that decreases the growth of tumor cells in animal models in one of the hardest to treat cancers — triple negative breast cancer.

It paves the way for developing new - generation drugs.

The convergence of several factors explains the trend: cheaper genetic sequencing technologies, the discovery of new oncogenes (genes that can cause a normal cell to become cancerous), a new generation of computers and bioinformatics that can analyze vast amounts of data, and a multibillion - dollar effort by researchers inside and outside the pharma industry to develop targeted drugs and companion diagnostics for cancer.

U.S. Secretary of State Hillary Clinton today declared that recent scientific advances in HIV / AIDS have created a «historic opportunity» to change the course of the pandemic and usher in a generation where no children are born with the virus, the risk of becoming infected plummets for teens and adults, and those who do become infected receive drugs that both ward off disease and make them less infectious.

«Scientists pave way for new generation of superbug drugs.»

«This could be very important for the next generation of space missions to the Moon and Mars and possibly have repercussions on the development of drugs on Earth.»

These first - generation direct - acting antivirals are the first of many direct acting antiviral drugs which will revolutionise treatment for HCV patients, including those who failed to respond to previous therapies.

For instance, a new generation of drugs — called PD1 inhibitors — that stop cancers turning off T - cells are producing good results when combined with other therapies.

This mechanism includes potential targets for next - generation drug discovery efforts to treat metabolic diseases including diabetes and obesity.

This mechanism includes potential targets for next - generation drug discovery efforts to treat met... more

The SSPC leads the way for next generation drug manufacture and spans the entire pharmaceutical production chain from synthesis of the molecule, to the isolation of the material, and formulation of the medicine.

Melanoma investigations point to new drug Virus - antibody combo shows promise for treating advanced melanoma New generation melanoma treatment could remove unwanted side effects Melanoma blood test saves lives

Genetically engineered mice now act as robust engines for the generation of diverse repertoires of affinity - matured, fully - human variable regions with intrinsic drug - like properties necessary for successful development including high potency, specificity, manufacturability, solubility and low risk of immunogenicity.

One of these promising new compounds is osimertinib, a third - generation EGFR - mutant inhibitor that has been approved by the US Food and Drug Administration (FDA) for EGFR T790M — positive NSCLC.

Due to the high efficiency of establishing organoid models from different tissues and diseases, such as cancer, organoid technology allows the generation of large living biobanks of tumor organoids that are amenable for middle - throughput drug screens and may allow personalized therapy design, as a complement to cell line and xenograft - based drug studies (7,19).

take a lead in developing the next generation of cancer cell lines and use cell lines to systematically explore in vitro sensitivity to large numbers of anticancer drugs and drug combinations in order to inform choice of cancer types for early drug trials.

Researchers now have a much better picture of how follicle - stimulating hormone (FSH), one of the most frequently used fertility drugs, works, and with it, ideas for creating a new generation of oral...

This discovery opens the path for industry, such as ICT and pharmaceutical, to cheaply print a host of electronic devices from solar cells to LEDs with applications from interactive smart food and drug labels to next - generation banknote security and e-passports.

Catalyse a new generation of research on the genetic basis of drug resistance and of other forms of biological adaptation in pathogen populations, by providing a standard analytical framework for the design and interpretation of genome - wide association studies.

Melov thinks that, given the resources, BAIT could handle up to 50 or 60 compounds, providing a next - generation resource for drug development.

Dr. Economides co-invented Cytokine Traps, VelociGene ®, and VelocImmune ®, all part of an integrated methodology for target discovery, validation, and the generation of biologic drugs such as the IL1 and VEGF traps, as well as therapeutic antibodies.

SAN DIEGO, March 28, 2017 (GLOBE NEWSWIRE)-- Invivoscribe ® Technologies Inc., a global company with decades of experience providing internationally standardized clonality and biomarker testing solutions for the fields of oncology, personalized molecular diagnostics ®, and personalized molecular medicine ®, reports that its next - generation sequencing (NGS) LymphoTrack ® Assay kits are being used by its LabPMM ® clinical laboratories, pharmaceutical partners, and cancer centers to identify and monitor chimeric antigen receptor T - cells (CAR - T) and engineered T - cell receptors in peripheral blood of subjects in support of immuno - therapeutic drug development and treatment regimen development for both hematologic and solid tumors.

She said that substitutes are available for some anticholinergic drugs, including a selective serotonin re-uptake inhibitor (SSRI) antidepressant like citalopram (Celexa) or fluoxitene (Prozac) for depression, or a second - generation antihistamine such as loratadine (Claritin) for allergy relief.

While known for helming the drug filled drama «Hustle & Flow,» Brewer proved his talent as a filmmaker by capturing the rebellious feelings of the current high school generation in «Footloose.»

Big Sur (R for nudity, sexuality and profanity) Beat Generation biopic about Jack Kerouac's (Jean Marc - Barr) descent into drugs and self - doubt at a retreat in Northern California following the success of his best - selling novel, «On the Road.»