Sentences with phrase «generation sequencing approaches»

Therefore, I am engaged in using, developing and combining new technologies, including: (1) super-resolution microscopy, (2) single molecule imaging, (3) genetic engineering, (4) next generation sequencing approaches and (5) mathematical and biophysical modeling.

Success of this project will provide answers to a number of major evolutionary questions, and will help develop innovative third - generation sequencing approaches for small organisms with large genomes, said Johanna Cannon.

Not exact matches

This quantitative, targeted, multiplexed approach leverages the power of next - generation sequencing and PCR technologies, and allows the researcher to obtain a molecular snapshot of the tumor microenvironment.

Dr. Funari's research interests include developing new approaches for obtaining mycobiome profiles in human disease and the translation of next generation sequencing applications into the clinic and personalized medicine.

To sequence DNA, the approach relies in part on an advanced technique known as next - generation sequencing, which is becoming increasingly widespread and affordable.

Genome - wide approaches such as next - generation sequencing are powerful to understand the information flow from genotype to phenotype, and the regulatory complexity accompanying life and disease.

We use next - generation sequencing to analyze circulating and shed biomarkers in order to develop better approaches for primary, secondary, and tertiary ovarian cancer prevention.

It will make use of cutting - edge approaches in vivo and in vitro, including mouse genetic models and next - generation sequencing of RNA and immunoprecipitated chromatin (RNA - seq and ChIP - seq).

Among vertebrates, the fish model displays easy high density breeding (short generation time), favourable biological peculiarities (accessibility and transparency of the eggs, genome sequenced for both species used on the platform), original technological approaches (confocal and two - photon microscopy), as well as a wide accessibility to fully transparent larvae usable up to 5 days after fertilization.

Newer methods, which leverage massively parallel sequencing approaches, are often referred to as Next - Generation Sequencsequencing approaches, are often referred to as Next - Generation SequencingSequencing (NGS).

Our lab blends computation and theory in close collaboration with experimentalists and clinicians, developing machine learning approaches and statistical models of next - generation sequencing data.

Information gained from this work will serve to enhance the clinical usefulness of findings from genomic sequencing (for example, next - generation sequencing or comprehensive genomic profiling), determine therapeutic approaches based on genomic findings, aid in the development of clinical trials and related options, and provide supportive rationale for exploring new therapies.

We developed a new approach to sequence generation for targeted base updates and used data from new genome mapping technologies and single haplotype resources to identify and resolve larger assembly issues.

As part of an ongoing functional genomic screening approach, we have been using microarray analysis and next generation sequencing to identify mouse genes that are specifically expressed in meiosis, and are likely involved in aspects of chromosome biology that are required for meiotic ploidy reduction.