Sentences with phrase «generation sequencing technologies»

But faster next - generation sequencing technology lets researchers sequence a much larger portion of the antibody arsenal.
His current research activities include the implementation of next generation sequencing technologies in a diagnostic setting and the use of this technology to better understand cancer etiology and treatment.
Proficient in applying conventional and next generation sequencing technology for viral quasispecies characterization.
Using second and third generation sequencing technologies, we aim at generating genomic data of novel bacterial and archaeal lineages, as well as of unchracterized protists.
The work became more feasible as next - generation sequencing technologies dropped the price for a detailed look at the genome of Palmophyllales» chloroplast — the energy - producing structure in a plant cell — to roughly US$ 8,000.
Second - generation sequencing technologies transformed the study of microbial transcriptomes.
The researchers used next generation sequencing technology, RNA sequencing, to reveal «in exquisite detail» the blueprint for making milk in the human mammary gland, according to Laurie Nommsen - Rivers, PhD, RD, IBCLC, a scientist at Cincinnati Children's and corresponding author of the study, published online in PLOS ONE, a journal of the Public Library of Science.
Next generation sequencing technologies in Academy labs have generated unprecedented amounts of genetic information for a thrilling new look at turtles» evolutionary history.
The CNAG - CRG makes efforts to promote the utilization of next - generation sequencing technology for rare disease applications.
Second and third generation sequencing technologies have revolutionised bacterial genomics.
Now, thanks to advances in next - generation sequencing technology, researchers are getting closer to understanding how these endangered animals fight the infection and detecting the illness early enough to minimize its spread.
Using three - dimensional modeling techniques, advanced computer simulation and next generation sequencing technology, faculty at UMass Medical School and the Massachusetts Institute of Technology (MIT) have resolved a long - standing debate that has consumed scientists ever since chromosomes were first observed under the light microscope by Walther Flemming in 1878.
The authors of this study have developed a universal primer set across flowering plants that amplifies 3 - 15 kilobase fragments, which can then easily be sequenced using recently developed next - generation sequencing technologies.
With the continual improvement of next - generation sequencing technologies, however, obtaining large molecular data sets is becoming much easier, and much cheaper.
Using next - generation sequencing technologies that were previously unavailable, Michael Gardner, a graduate research assistant, and Jianying Wang, a senior research associate in Mitchum's lab, made a remarkable new discovery — nematodes possess the ability to produce a second type of peptide that can effectively «take over» plant stem cells that are used to create vital pathways for the delivery of nutrients throughout the plant.
Using next - generation sequencing technology, the researchers also were able to detect hundreds of unique bacterial species and confirmed that children with ASD harbored distinct and less diverse gut bacterial composition.
An effective way to solve this problem is through the use of multiplexed polymerase chain reactions (PCR) run with barcoding, which offers the possibility of sequencing hundreds of unique samples per run using next generation sequencing technology.
Using next - generation sequencing technology, the scientists examined the transcriptome — every gene activated in the embryo — to create a snapshot of how baby urchins responded physiologically.
Nucleic acid was extracted from five of the shower hoses and processed using next - generation sequencing technology.
A University of Colorado Cancer Center study published in the journal Oncogene used next - generation sequencing technologies to perform the most detailed DNA - based analysis to date of 25 commonly used bladder cancer cell lines, allowing researchers to match patient tumors with their closest genetic cell line match, and demonstrated genetic alterations that may make cells more or less sensitive to common therapies.
If it can be modified to rely entirely on next - generation sequencing technology, he says, researchers should theoretically be able to identify not just which species are dying, but also which pathogens killed them.
Dr. James Beck of Wichita State University and Dr. John Semple, at the University of Waterloo, have collaborated on a new study highlighting the role of herbarium sampling coupled with cutting - edge next - generation sequencing technologies to better understand plant diversity.
In collaboration with Foundation Medicine, Inc. of Cambridge, Massachusetts, tissue specimens were analyzed through Next Generation Sequencing technology.
With recent, rapid advances in next - generation sequencing technologies, large genomic data sets are becoming increasingly obtainable.
«Next - generation sequencing technology has allowed us to find new causes of genetic diseases in much smaller families,» explained the study's lead author, William Motley, MD, PhD, a resident physician in Medicine.
He and his laboratory are currently focused on using next generation sequencing technologies to identify the causative genes for pediatric cancers.
Genome researcher Elaine Mardis of Washington University in St. Louis in Missouri cautions that because the 1000 Genomes Project participants» genomes weren't sequenced in depth and were done when next - generation sequencing technologies were very new, MacArthur's team may have missed some loss - of - function variants.
In loblolly pine, these were first generated with > 300,000 Sanger - sequenced expressed sequence tags (ESTs) and later as de novo assemblies from next - generation sequencing technologies (Allona et al. 1998; Kirst et al. 2003; Cairney et al. 2006; Lorenz et al. 2006, 2012).
The bacteria and other microbes that live within the human body are thought to influence not only digestive health, but metabolic and autoimmune diseases as well, possibly even psychiatric and neurodevelopmental disorders. The field is being propelled by next - generation sequencing technology, and Nature had to publish an editorial guarding against hype (a major theme: correlation is not causation).
Methodology challenges in studying human gut microbiota — effects of collection, storage, DNA extraction and next generation sequencing technologies — Marina Panek — Scientific Reports
deCODE's discovery capabilities combine its extensive population and genetic resources, including DNA samples and medical data, complete genealogical information, next generation sequencing technology, and deCODE's proprietary bioinformatics and statistical capabilities.
The rapid advance of next - generation sequencing technologies, particularly in the last several years, has almost seemed like something out of a science fiction novel.
We use Next Generation Sequencing technology to read your DNA, and then store and protect the resulting data.
April 2012 - New research: Illuminating embryonic stem cells Collaboration between two EU funded projects «Heroic» and «EuroSyStem», has provided new insights into embryonic stem cells The teams used next generation sequencing technology to examine two key properties of the cells that influence their identity and behaviour: gene expression and gene regulation.
The paper is the first outcome of the workshop arranged by the JRC on «Next - generation sequencing technologies and antimicrobial resistance» held October 4 - 5 last year in Ispra, Italy.
Follow - up of these studies, including work on long and short non-coding RNA and whole - exome sequencing, are performed using next - generation sequencing technology.
Bertout proposes to use new barcoding technologies she developed in the Bielas Lab to build upon Next Generation Sequencing technologies and enable exquisitely sensitive cancer - specific mutation detection.
The emergence of high - throughput, next - generation sequencing technologies has dramatically altered the way we assess genomes in population genetics and in cancer genomics.
Next - generation sequencing technologies are said to be ushering in a new era of cancer genomics.
With the development of Next Generation Sequencing technologies, the amount of data generated has reached an unprecedent level.
This is due in large part to the maturation of so - called next - generation sequencing technology, which allows the DNA of the entire genome to be sequenced far less expensively and with far greater accuracy than ever before.
The goal of the SU2C - MRA Melanoma Dream Team Translational Cancer Research Grant led by Jeffrey M. Trent, Ph.D., and Patricia M. LoRusso, D.O., is to use next - generation sequencing technology to examine both the normal and cancer genome of patients with metastatic melanoma.
New results from a research group lead by SciLifeLab faculty member Richard Rosenquist Brandell shows that next - generation sequencing technology can provide equally reliable results as previous methods.
I am also active in applying next - generation sequencing technology to identify specific genomic changes in cancers that can be therapeutically targeted.
As we continue to apply next - generation sequencing technologies to cancer genomes, we're discovering hundreds of putative somatic mutations.
On the study of microbial transcriptomes using second - and third - generation sequencing technologies
Through his collaboration with the MalariaGEN Anopheles 1000 Genomes (Ag1000g) Project, Martin and his group are using next - generation sequencing technologies to address aspects of the biology of Anopheles gambiae that impact upon the sustainable control of malaria.
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