Sentences with phrase «generation sequencing technology»

Proficient in applying conventional and next generation sequencing technology for viral quasispecies characterization.

Using next - generation sequencing technology, we have generated a complete, high - quality mt genome from a stratigraphically validated 130,000 - to 110,000 - year - old polar bear jawbone.

The planTrue ™ carrier screening from True Health employs industry - leading next - generation sequencing technology to detect whether a patient is a carrier for conditions such as cystic fibrosis, spinal muscular atrophy, fragile X, and many others.

I am also active in applying next - generation sequencing technology to identify specific genomic changes in cancers that can be therapeutically targeted.

New results from a research group lead by SciLifeLab faculty member Richard Rosenquist Brandell shows that next - generation sequencing technology can provide equally reliable results as previous methods.

This is due in large part to the maturation of so - called next - generation sequencing technology, which allows the DNA of the entire genome to be sequenced far less expensively and with far greater accuracy than ever before.

Follow - up of these studies, including work on long and short non-coding RNA and whole - exome sequencing, are performed using next - generation sequencing technology.

The CNAG - CRG makes efforts to promote the utilization of next - generation sequencing technology for rare disease applications.

April 2012 - New research: Illuminating embryonic stem cells Collaboration between two EU funded projects «Heroic» and «EuroSyStem», has provided new insights into embryonic stem cells The teams used next generation sequencing technology to examine two key properties of the cells that influence their identity and behaviour: gene expression and gene regulation.

deCODE's discovery capabilities combine its extensive population and genetic resources, including DNA samples and medical data, complete genealogical information, next generation sequencing technology, and deCODE's proprietary bioinformatics and statistical capabilities.

«Next - generation sequencing technology has allowed us to find new causes of genetic diseases in much smaller families,» explained the study's lead author, William Motley, MD, PhD, a resident physician in Medicine.

If it can be modified to rely entirely on next - generation sequencing technology, he says, researchers should theoretically be able to identify not just which species are dying, but also which pathogens killed them.

But faster next - generation sequencing technology lets researchers sequence a much larger portion of the antibody arsenal.

The researchers used next generation sequencing technology, RNA sequencing, to reveal «in exquisite detail» the blueprint for making milk in the human mammary gland, according to Laurie Nommsen - Rivers, PhD, RD, IBCLC, a scientist at Cincinnati Children's and corresponding author of the study, published online in PLOS ONE, a journal of the Public Library of Science.

The authors of this study have developed a universal primer set across flowering plants that amplifies 3 - 15 kilobase fragments, which can then easily be sequenced using recently developed next - generation sequencing technologies.

With the continual improvement of next - generation sequencing technologies, however, obtaining large molecular data sets is becoming much easier, and much cheaper.

Using next - generation sequencing technologies that were previously unavailable, Michael Gardner, a graduate research assistant, and Jianying Wang, a senior research associate in Mitchum's lab, made a remarkable new discovery — nematodes possess the ability to produce a second type of peptide that can effectively «take over» plant stem cells that are used to create vital pathways for the delivery of nutrients throughout the plant.

His current research activities include the implementation of next generation sequencing technologies in a diagnostic setting and the use of this technology to better understand cancer etiology and treatment.

A University of Colorado Cancer Center study published in the journal Oncogene used next - generation sequencing technologies to perform the most detailed DNA - based analysis to date of 25 commonly used bladder cancer cell lines, allowing researchers to match patient tumors with their closest genetic cell line match, and demonstrated genetic alterations that may make cells more or less sensitive to common therapies.

Dr. James Beck of Wichita State University and Dr. John Semple, at the University of Waterloo, have collaborated on a new study highlighting the role of herbarium sampling coupled with cutting - edge next - generation sequencing technologies to better understand plant diversity.

With recent, rapid advances in next - generation sequencing technologies, large genomic data sets are becoming increasingly obtainable.

Genome researcher Elaine Mardis of Washington University in St. Louis in Missouri cautions that because the 1000 Genomes Project participants» genomes weren't sequenced in depth and were done when next - generation sequencing technologies were very new, MacArthur's team may have missed some loss - of - function variants.

He and his laboratory are currently focused on using next generation sequencing technologies to identify the causative genes for pediatric cancers.

In loblolly pine, these were first generated with > 300,000 Sanger - sequenced expressed sequence tags (ESTs) and later as de novo assemblies from next - generation sequencing technologies (Allona et al. 1998; Kirst et al. 2003; Cairney et al. 2006; Lorenz et al. 2006, 2012).

Methodology challenges in studying human gut microbiota — effects of collection, storage, DNA extraction and next generation sequencing technologies — Marina Panek — Scientific Reports

Using second and third generation sequencing technologies, we aim at generating genomic data of novel bacterial and archaeal lineages, as well as of unchracterized protists.

Bertout proposes to use new barcoding technologies she developed in the Bielas Lab to build upon Next Generation Sequencing technologies and enable exquisitely sensitive cancer - specific mutation detection.

Next - generation sequencing technologies are said to be ushering in a new era of cancer genomics.

Second - generation sequencing technologies transformed the study of microbial transcriptomes.

On the study of microbial transcriptomes using second - and third - generation sequencing technologies

Through his collaboration with the MalariaGEN Anopheles 1000 Genomes (Ag1000g) Project, Martin and his group are using next - generation sequencing technologies to address aspects of the biology of Anopheles gambiae that impact upon the sustainable control of malaria.

About Blog Next generation sequencing technologies have begun to totally revamp the way high - throughput biology is done and it is slowly knocking the doors of hospitals.

Not exact matches

The test — which currently costs $ 99.95 but originally was $ 199.95 — is different from AncestryDNA and 23andMe in that it uses next - generation sequencing instead of genotyping technology.

The technology, available through Genesis Genetics or Good Start Genetics, involves next - generation, or next - gen, sequencing.

This new technology is dubbed next generation sequencing.

«It can handle multiple biomarker technologies simultaneously, such as complex flow cytometry, next - generation sequencing, immunosequencing, epigenetic profiling, and other types of asssys measuring biological variation as well,» says Marshall.

To test their hypothesis, the researchers used next - generation sequencing (NGS) technology to sequence the complete set of coding variants from the genomes of individuals from seven populations within and outside Africa, i.e. from the Democratic Republic of Congo, Namibia, Algeria, Pakistan, Cambodia, Siberia and Mexico.

From Sewers to Streetlights, Microbes Are Grabbing Civil Engineers» Attention An understanding of how to cultivate a healthy «microbiome» in our living areas is now getting off the ground, boosted by next - generation DNA sequencing technologies.

This quantitative, targeted, multiplexed approach leverages the power of next - generation sequencing and PCR technologies, and allows the researcher to obtain a molecular snapshot of the tumor microenvironment.

The next generation of sequencing technology will take results to a new level

NIH scientists then searched for disease - causing genes using next - generation DNA sequencing, technology that allows researchers to sequence DNA quickly and economically.

Using next - generation RNA sequencing and other advanced technologies, the researchers identified a previously unknown gene involved in betalain synthesis and revealed which biochemical reactions plants use to convert the amino acid tyrosine into betalains.

Using next - generation sequencing (NGS) technology, researchers were able to pinpoint specific areas of a person's DNA to more effectively diagnose genetic forms of high - cholesterol, which markedly increase risk for heart attack and stroke.

Clearly, next - generation sequencing (NGS) technologies have had a trailblazing effect on career opportunities.

Existing technology, known as next - generation sequencing (NGS), measures genomes derived from millions of cells versus the newer method for single - cell sequencing, called Monovar.

The convergence of several factors explains the trend: cheaper genetic sequencing technologies, the discovery of new oncogenes (genes that can cause a normal cell to become cancerous), a new generation of computers and bioinformatics that can analyze vast amounts of data, and a multibillion - dollar effort by researchers inside and outside the pharma industry to develop targeted drugs and companion diagnostics for cancer.

The Human Microbiome Project, funded by the US National Institutes of Health, has now used next - generation DNA sequencing technology to study these microbes straight from the source.

Among these is BRG1 (also called SMARCA4) and the latest generation - sequencing technologies have extended these findings to other tumor types evidencing that BRG1 inactivation is widespread in cancer.

For one thing, sequencing technologies continue to develop at a breakneck pace, and, according to Willerslev, as third - generation technologies such as nanopore sequencing are applied to ancient - DNA work, researchers will be able to probe even deeper into the biological past.

This short course will discuss the current state of PGS and PGD, latest advances in technologies such as next - generation sequencing, and the challenges we face with mosaic embryos.