Sentences with phrase «generation sequencing tools»

«Next generation sequencing tools were used to profile patients» tumors,» said Razelle Kurzrock, MD, director of the Center for Personalized Cancer Therapy at UC San Diego Moores Cancer Center.

Not exact matches

Apart from using a host of cutting - edge molecular techniques such as Next Generation Sequencing or NGS, the researchers also had to develop specific bioinformatic tools for analysing large amounts of genomic data.
The researchers then compared the expression of all genes in six parts of the brain of the two bird species using state - of - the - art molecular techniques, including next - generation sequencing — the first time these tools have been used to find brain properties related to innovation and problem - solving in wild birds.
«The sequence will make it possible to develop new, more effective selective breeding tools that will make us even better at choosing parent fish with desired traits for the next generation of salmon,» says Mr Arnesen.
The TrueMethyl Whole Genome (TMWG) integrated workflow system for processing DNA samples includes all - in - one reagents for sample conversion, library creation, and indexing, combined with bioinformatics tools to enable accurate DNA modification analysis through next - generation sequencing methods.
Engineered cells are then validated via next - generation sequencing and analysis of the modified genomic loci with custom analytical tools developed by our bioinformatics team.
Explore one of the world's largest repositories of next - generation sequencing data and analysis tools for pediatric cancer.
With the effort to sequence the entire human genome speeding toward completion, some researchers are now focusing their energy on developing the next generation of tools that can be used to extract...
We designed PhylOTU, the first computational tool for estimating the taxonomic composition of metagenomic samples from short, next - generation sequencing reads.
In a study being published online today in the journal Cell, researchers in the laboratory of Gladstone Senior Investigator Benoit Bruneau, PhD, employed stem cell technology, next - generation DNA sequencing and computing tools to piece together the instruction manual, or «genomic blueprint» for how a heart becomes a heart.
Metagenomics: Tools and Insights for Analyzing Next - Generation Sequencing Data Derived from Biodiversity Studies — Anastasis Oulas — Bioinform Biol Insights — May 2015
Developed in collaboration with the Laboratory Medicine, Information Technology and Health Science Research departments of Mayo Clinic Geneticist Assistant NGS Interpretative Workbench, is a web - based tool for the control, visualization, interpretation and historical knowledge base of next generation sequencing data targeted at specific genes for the purpose of identifying potentially pathogenic variants associated with specific conditions such as hereditary colon cancer.
Her laboratory focuses on (1) the use of next generation sequencing to define the microbiome and host immunologic features in patients with human diseases and (2) developing custom computational tools for the identification of novel human commensals and pathogens in these inpatient populations, and (3) using statistical and functional biological methods to understand the complex interplay between the human microbiome and host biology.
The advent of a miniaturised DNA sequencing device with a high - throughput contextual sequencing capability embodies the next generation of large scale sequencing tools.
In light of these limitations, next - generation sequencing (NGS) represents a more appropriate technique for analyzing these type of samples, mainly due to the high resolving power that characterizes NGS platforms conjointly with bioinformatics tools.
Here, we demonstrate the feasibility of classical genetic screening in mammalian systems by using haploid cells, chemical mutagenesis and next - generation sequencing, providing a new tool to explore mammalian genetic interactions.
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