Sentences with phrase «genes affect different»

Studying how genes affect different drugs manufactured by different companies gives Poirier greater influence on future drug development, he feels, which would not be possible if he was employed at any one pharmaceutical research lab.

Each obesity - related gene affects a different aspect of weight control.

Not exact matches

These conditions are each caused by mutations in a particular gene, and affect different enzymes involved in breaking down galactose.

It may be that those 37 different genes could affect the personality of the resulting child.

Complex traits like the ones in the study are each influenced by many different genes, while at the same time, several different traits can be affected by the same genes.

Dwivedi cautioned, however, that each miRNA can affect many different genes, so its involvement in depression may not be clear - cut.

But as some miRNAs regulate many different genes, and each gene is affected by many different miRNAs, their exact role in cancer is tough to pin down.

Comparisons of the Neandertal genome to the genomes of five present - day humans from different parts of the world identify a number of genomic regions that may have been affected by positive selection in ancestral modern humans, including genes involved in metabolism and in cognitive and skeletal development.

The clones also appeared to have an effect on the gene expression of the pregnant cows themselves; on day 34, some uterus tissue showed grossly different gene expression, which could affect the placenta.

What's different about Church's machine is that it can target the genes that affect a particular characteristic and alter them in specific ways.

«The new FOP model already has shed light on the disease process in FOP by showing that the mutated gene can affect different steps of bone formation,» Hsiao said.

She identified a region on chromosome 8 where the affected family members had distinctly different genes.

MicroRNAs are found throughout the body and affect how genes are expressed depending on different conditions, like disease or injury.

Different genes could affect the same pathway, meaning that the different genetic anomalies found in people with ASD could potentially all be affecting similar Different genes could affect the same pathway, meaning that the different genetic anomalies found in people with ASD could potentially all be affecting similar different genetic anomalies found in people with ASD could potentially all be affecting similar pathways.

Interaction between different affected genes may also occur; this should be investigated in the future.

The study is the first to look at these different biological markers, as well has how the gene's impact on dopamine production specifically affects Caucasian populations.

Blokesch's lab grew the cholera bacterium with different sugars (e.g. glucose, sucrose) and starch from potatoes and rice to see how each would affect the cholera toxin genes.

Both De Luca and Marinkovich's teams are exploring a similar gene therapy for another major form of the disease, called dystrophic EB, caused by a different genetic error affecting a larger protein.

So even though the genes that cause ALS and SMA are different, they might share a common pathway that affects motor neuron structure and function.»

At Emory, the pause has halted not only the CEIRS project with the lab - attenuated PR8 strain, but also a research grant project headed by Anice Lowen that is looking at how the cell types targeted by two different influenza viruses affect their propensity to exchange genes.

The researchers found that 18 different genes harbored cancer - predisposing mutations in those 125 families, but each affected person carried a mutation in only one gene.

Because previous studies had suggested that different alleles (versions) of the IL - 28B gene affect immune responses, the researchers determined which alleles the transplant recipients carried.

Neves and Chess hypothesize that a different version of the gene may affect humans similarly.

So far, scientists have found that different populations of living humans have inherited the Neandertal version of genes that cause diabetes, lupus, and Crohn's disease; alter immune function; and affect the function of the protein keratin in skin, nails, and hair.

There are some data on how groups of genes are impacted by one chemical, and other genes are affected by different chemicals.

Segal: «We can not change our genes, but we now know that we can affect — and even reshape — the composition of the different kinds of bacteria we host in our bodies.

Although TMAdV was found to be highly divergent from other adenoviruses, different isolates of TMAdV from 3 affected titi monkeys were remarkably conserved, sharing 100 % identity across the full - length hexon gene (data not shown).

The current work shows that changes in the genetic code of a particular gene can control epigenetic marks at different genes, implying that a gene's genetic code can affect whether other genes are turned on and off, which makes it important to understand the function of all genes involved, not just the one with the so - called misspelling.

Although this compound exhibits a preference for AT - rich regions, overall it is expected to affect expression of a multitude of different genes involved in diverse biological functions.

More than 72 different MD have been described so far and have been linked to primary genetic perturbations affecting 46 different genes.

The histone proteins are decorated with different marks, which can affect the various activities of the modified DNA such as transcription, gene silencing, imprinting and replication.

To understand why skin cells in diverse parts of the body have different characteristics - how cells know their «positional identities» - a fact that guides the diagnosis and treatment of many skin diseases, Dr. Chang and his colleagues are seeking to define in molecular terms how the expression of different genes in stromal cells determines their ability to affect the development of skin cells.

«Mutations in the tumours will affect signalling in different ways depending on which gene is affected, but different mechanisms seem to converge to produce a common phenotype of invasiveness», says Simona.

A new primer pair designed from the sequenced E gene TV - 3 (f) and TV - 3 (r) was used to detect viral genes in clinical samples collected from different affected regions in China.

Although most adult leukemias involving MLL affect a different part of the gene, the breakpoints found in infant leukemias and secondary leukemias occur predominantly in the small region altered by the bioflavonoids.

Targeting different regions of the gene is also useful in case the gene has a weird mutation that you didn't know about (which could affect the ability of the gRNA to bind).

In comparing different lines, we want to find genes associated with what we call quantitative traits — genes that affect traits of importance to agriculture, everything from the size of the seeds to when the plant flowers to whether it can tolerate drought or dampness.

Epigenetic modifications in bacteria, such as DNA methylation, have been shown to affect gene regulation, thereby generating cells that are isogenic but with distinctly different phenotypes.

The CDKN2A gene is very unusual in that mutations can also affect another, quite different, protein called ARF.

Occasionally there are mutations that affect a different gene, called the CDK4 gene, but these were also uncommon.

And its not just one gene playing with your waistline; different genes determine levels of hormones that affect hunger and fullness when you eat.

If it affects your ovaries / testes, then your offspring will have different genes than you.

The research, published in the journal Frontiers in Immunology, reviews over a decade of studies analysing how the behaviour of our genes is affected by different MBIs including mindfulness and yoga.

A 2014 study from UC Berkley that found that long - term marital satisfaction over time can be affected based on the different variations of this gene that people have.

Because there is more than one form of PRA, if there should happen to be a second form in the breed and your dog had the genes for that type it would be possible to test your dog «for PRA» using the PRCD test with clear results when the dog is actually affected — but with a different form of PRA.

One mutation, which is complete deletion of the CNGB3 gene, affects Malamutes and Australian Shepherds, while a different single nucleotide mutation in the same gene causes Cone Degeneration in the GSHP breed.

Since hip dysplasia is a polygenic disorder controlled by several gene pairs, the disease affects individual dogs due to different genetic combinations.

Two related potassium (K +) channel defects in benign familial neonatal convulsions (BFNC) have recently been identified.9 10 A defect in a receptor for a different neurotransmitter (acetylcholine) has previously been identified in a family with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) 11, which was later shown to affect calcium (Ca +) movement.12 In humans, so far, there has not been any success in identifying genes associated with more common primary epilepsy syndromes such as juvenile absence epilepsy and juvenile myoclonic epilepsy (JME).13 No gene or marker linked to an epilepsy gene has been identified in any dog breed, as yet.

Such interplay between genes and environment may channel individual development into different trajectories early in life and affect the long - term development of mental health and disorder.