The tendency of more intelligent people to live longer has been shown, for the first time, to be mainly down to
their genes by new research published in the International Journal of Epidemiology today.
Not exact matches
Angling to be the go - to marketplace for these
gene - based businesses, Helix, the spin out from genetic testing
research and technology giant Illumina, has held a first close on a planned $ 200 million funding round led
by new investor DFJ Growth.
New research suggests it may be possible to restore susceptibility to antibiotics in superbugs
by locating and inactivating
genes that promote resistance.
Therefore, the plants with
genes for superhot chiles had more offspring than the chiles with other parents.The mutation was discovered in 2016
by Dr. Peter Cooke of the
New Mexico State University Core University
Research Resources Laboratory.
«Cancer cells disguise themselves
by switching off
genes,
new research reveals: A genome - wide map of the
genes switched off in aggressive tumors reveals a «signature».»
In the
new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores
gene expression and function using an epigenetic mechanism, where
gene changes are caused
by influences other than DNA sequences.
A genetics
research team at Johns Hopkins Medicine has solved a dilemma facing researchers who use genomewide association studies (GWAS)
by developing a
new approach that strategically «filters» which
genes are worth further study.
New research at the University at Buffalo reveals the first evidence that it may be possible to use a single compound to alleviate the behavioral symptoms
by targeting sets of
genes involved in the disease.
New research is pointing to a different possibility: There may be no adaptive advantage provided
by schizophrenia in and of itself, but rather from some
genes that contribute to the disease.
And since the
newest research suggests that extreme longevity is determined largely
by genes, you might also want to know, as I do, whose
genes you've inherited (my father died at 93, my mother at 71) and which aspects of lifestyle, diet, and the environment influence those
genes most.
A
new study from the Institute of Food
Research has uncovered a mechanism
by which Salmonella bacteria organise the expression of
genes required for infection.
For his part, Collins, who has led NIH since 2009 and been kept on
by the Trump administration, pointed to an array of promising NIH activities, including the development of
new technologies to provide insights into human brain circuitry and function through the Brain
Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the
gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disease.
Being able to acquire
new technologies, as well as becoming more innovative internally
by venturing into
new research areas, such as stem cell and
gene therapy
research, have allowed Genzyme to maintain its edge.
The
new «CrispRGold» program written
by PhD student Robin Graf from the MDC
research group headed
by Prof. Klaus Rajewsky makes it significantly easier to disable specific
genes.
A molecule in cells that shuts down the expression of
genes might be a promising target for
new drugs designed to treat the most frequent and lethal form of brain cancer, according to a
new study
by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove
Research Institute (OSUCCC — James).
This
new research demonstrates a positive feedback loop between the proteins expressed
by these
genes that promote GBM growth and survival.
The study, which has identified more than 200 rare variants inherited
by children, determines that
genes YWHAZ and DRP2, among others, are
new candidates in the
research on autism genetic basis.
New research suggests that fluid driven
by tiny swirling hairs called cilia may activate certain
genes in the growing embryo that lay the groundwork for this asymmetry.
«Because many broadly expressed
genes that play key roles in essential cellular functions are under the control of cell - specific enhancers, the ability to affect enhancer function
by knocking down eRNAs could potentially provide a
new strategy for altering
gene expression in vivo in a cell - specific manner,» said Glass, noting that in his
research, anti-sense oligonucleotides were developed in conjunction with Isis Pharmaceuticals, which suppressed enhancer activity and reduced expression in nearby
genes.
Years of diabetes
research carried out on mice whose DNA had been altered with a human growth hormone
gene is now ripe for reinterpretation after a
new study
by researchers at KU Leuven confirms that the
gene had an unintended effect on the mice's insulin production, a key variable in diabetes
research.
Now a
new study led
by scientists at The Scripps
Research Institute (TSRI) and the Scripps Translational Science Institute (STSI) suggests that «molecular autopsies» may be valuable in detecting
gene mutations responsible for a sudden death.
A single
gene appears to play a crucial role in coordinating the immune system and metabolism, and deleting the
gene in mice reduces body fat and extends lifespan, according to
new research by scientists at the Jean Mayer USDA Human Nutrition Research Center (USDA HNRCA) on Aging at Tufts University and Yale University School of M
research by scientists at the Jean Mayer USDA Human Nutrition
Research Center (USDA HNRCA) on Aging at Tufts University and Yale University School of M
Research Center (USDA HNRCA) on Aging at Tufts University and Yale University School of Medicine.
Their
research team currently is testing the potential effect of the unique differences of the giraffe's FGFRL1
gene by introducing these changes into mice using the
new CRISPR
gene - editing methods.
New research led
by UC San Francisco scientists has revealed that mutations in a
gene linked with brain development may dispose people to multiple forms of psychiatric disease
by changing the way brain cells communicate.
A
new function now described for the protein dDsk2
by the team headed
by Ferran Azorín, group leader at the Institute for
Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene exp
Research in Biomedicine (IRB Barcelona) and CSIC
research professor, links ubiquitin receptors for the first time with the regulation of gene exp
research professor, links ubiquitin receptors for the first time with the regulation of
gene expression.
The
gene that controls shell thickness, creatively named SHELL, was identified in 2013
by researchers at Orion, Cold Spring Harbor Laboratory in
New York and the Malaysian Palm Oil Board (MPOB), a government
research institute based near Kuala Lumpur.
Previous
research by Professor Keevil and Dr Warnes has proved copper's efficacy against norovirus, influenza and hospital superbugs, such as MRSA and Klebsiella, plus stopping the transfer of antibiotic resistance
genes to other bacteria to create
new superbugs.
A rare
gene variant discovered
by UCL (University College London) scientists is associated with an increased risk of developing schizophrenia, bipolar disorder and alcoholism, confirms
new research.
Human teeth evolved from the same
genes that make the bizarre beaked teeth of the pufferfish, according to
new research by an international team of scientists.
To date, however, this
research has been slowed
by the inefficiency of the viruses that are now used as vectors to carry
new genes into cells.
But
new research led
by University of Pennsylvania scientists suggests that mutations in an X chromosome
gene called TEX11 are responsible for a significant number of cases of infertility — an estimated 1 percent of cases of non-obstructive azoospermia.
«Cells rank
genes by importance to protect them, according to
new research.»
A
new study,
by researches at Uppsala University, shows now that the memory of a heart attack can be stored in our
genes through epigenetic changes.
The
new research, however, could potentially open a way to expand our regenerative playbook
by manipulating the activity of
genes such as Lin28a or mimicking their effects.
New research led
by the Karolinska Institutet, Sweden and the University of Glasgow, Scotland, has identified a link between a human
gene and the composition of human gastrointestinal bacteria.
The method, developed
by Professor Erik Sonnhammer's
research group, associates experimentally derived
gene lists and known pathways in a
new way.
Our strategy is to use screening techniques to uncover
new players followed
by validation in
gene targeted mice (conventional and conditional transgenesis) in order to test novel treatment strategies in a joint translational
research activity.
Vogelstein also argued that the
new research about random mutations should offer comfort to people who develop cancer despite having «near - perfect lifestyles,» as well as to parents who are worried that they somehow «gave» their children cancer, either
by passing on a harmful
gene or inadvertently exposing them to an environmental toxin.
By probing the three dimensional structure of this protein complex, called RNA - Induced Initiation of Transcriptional
gene Silencing (RITS), scientists from Cold Spring Harbor Laboratory (CSHL) and their collaborators at St. Jude's
Research Hospital have discovered
new details of how its various parts or «domains» contribute to heterochromatin assembly and
gene silencing.
New research led
by the University of Bristol has found that
genes in the brain that play a crucial role in behavioural adaptation to stressful challenges are controlled
by epigenetic mechanisms.
A
research team led
by an award - winning genomicist at Western University has developed a
new method for identifying mutations and prioritizing variants in breast and ovarian cancer
genes, which will not only reduce the number of possible variants for doctors to investigate, but also increase the number of patients that are properly diagnosed.
Research funded
by E-Rare has a great impact on life patients supporting the understanding of the natural history of disease, the discovery of
new causative deases
genes or the discovery of innovative therapeutic approaches.
Sigma - Aldrich ® and the Institute of Molecular Genetics, Czech Center for Phenogenomics, Establish CRISPR Core Lab Collaboration ST. LOUIS, Jan. 29, 2015 / PRNewswire / — Sigma - Aldrich Corporation's (NASDAQ: SIAL)
Research business unit, which supports scientific research by supplying products, services and solutions, today announced it has entered into a new gene editing collaboration with the Czec
Research business unit, which supports scientific
research by supplying products, services and solutions, today announced it has entered into a new gene editing collaboration with the Czec
research by supplying products, services and solutions, today announced it has entered into a
new gene editing collaboration with the Czech Center
An alternative approach pioneered
by Deepak Srivastava, MD, director of cardiovascular and stem cell
research at Gladstone, used
genes to convert scar - forming cells in the heart of animals into
new muscle that improved the function of the heart.
New research led
by the School of Medicine shows that an influential 2003 study about the interaction of
genes, environment and depression may have missed the mark.
«Snow Leopards,» Part of
New Series, «Biodiversity of the World Conservation From
Genes to Landscapes» was edited
by Dr. Tom McCarthy and Dr. David Mallon, recognised snow leopard experts with more than 50 years of collective experience in
research and conservation of the species.
The
research spending comes at a time of growing interest in synthetic biology, particularly surrounding the potential presented
by new gene - editing techniques.
The CRISPR - Cas9 system and later advances, also developed
by Zhang, are easy to execute with almost endless possibility for
new research enabling scientists to change, delete, and replace any
genes of any animal.
New research suggests that people who have had a concussion can experience more memory problems and atrophy in areas of the brain that are typically damaged
by the disease if they have those high - risk
genes.
This
new research, conducted
by scientists in Belgium and published in the journal Nature Communications, found that in yeast, the presence of high levels of glucose (sugar) can activate a
gene called Ras — the role of which is to regulate cell generation, both in mammals and in yeast — which is often found in tumours.