Sentences with phrase «genes coding for»

Epigenetic modifications of promoter regions that influence the transcription of genes coding for crucial protein products can be induced by the environment.

Mutations for monogenic epilepsies have been found primarily in genes coding for ion channels 32 as well as in two different proteins that may be involved in neurogenesis 33.

I've taken the example of three genes coding for Phase 1 detoxification.

Intestinal permeability was assessed by Ussing chamber; epithelial cell (EC) ultra-structure by electron microscopy; RNA expression of genes coding for junctional proteins by Q - real - time PCR; immune response by in - vitro antigen - specific T - cell proliferation and cytokine analysis by cytometric bead array; intestinal microbiota by fluorescence in situ hybridization and analysis of systemic antibodies against intestinal microbiota by surface staining of live bacteria with serum followed by FACS analysis.

Design and evaluation of useful bacterium - specific PCR primers that amplify genes coding for bacterial 16S rRNA

To explore the possibility of common genetic pathways within the respective pathophysiologies, nine ADHD candidate single nucleotide polymorphisms (SNPs) in seven genes were tested for association with PD in 5333 cases and 12,019 healthy controls: one variant, respectively, in the genes coding for synaptosomal - associated protein 25 k (SNAP25), the dopamine (DA) transporter (SLC6A3; DAT1), DA receptor D4 (DRD4), serotonin receptor 1B (HTR1B), tryptophan hydroxylase 2 (TPH2), the norepinephrine transporter SLC6A2 and three SNPs in cadherin 13 (CDH13).

vector - a bacterium or virus that does not cause disease in humans and is used in genetically engineered vaccines to transport genes coding for antigens into the body to induce an immune response.

The symposium features presentations by Philippa Marrack and John Kappler talking on the T cell repertoire; William Paul on interleukin 4 as a prototypic immunoregulatory cytokine; Timothy Springer on lymphocyte trafficking; Pamela Bjorkman on structural studies of MHC and MHC - related proteins, and Jack Strominger on peptide presentation by class I and II MHC proteins; Thierry Boon on genes coding for tumor rejection antigens, including the first tumor antigen, MAGE - 1; and Philip Greenberg on the modification of T cells for adoptive therapy by retroviral - mediated gene insertion Since then, the symposia series has attracted leading immunologists in the cancer vaccine and antibody fields, providing them with a comprehensive view of the promises and challenges in the development of cancer immunotherapies.

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.

«It has more than 800 genes coding for surface proteins and that's a huge number to have,» Carlton says.

But intriguingly, the Lokiarchaea appear to have more than 100 genes coding for sophisticated cellular functions such as deforming cell membranes and forming and transporting bubble - like vesicles around the cell — functions that are usually only seen in eukaryotes like us.

When the chimp and human genomes are compared, some of the clearest cases of nucleotide differences are found in genes coding for transcription factors.

It is perhaps thus likely that that these damaged genes coding for psychiatric diseases are overrepresented in women with fertility problems, and, if transferred to their offspring, this may at least partly explain the increased risk of psychiatric diseases.»

By selectively adding or deleting stretches of DNA in the (artificially) fertilized cell, scientists could knock out genes for a disease like diabetes or insert genes coding for extra height or intelligence.

Previous work in Atlantic salmon has shown that the diversity of genes coding for the MHC binding site is lower in animals that typically live in lower temperature conditions.

She has tracked dramatic increases in the prevalence of several genes and suites of genes coding for drug resistance.

By comparing proteomic and RNA - sequencing data from people on different exercise programs, the researchers found evidence that exercise encourages the cell to make more RNA copies of genes coding for mitochondrial proteins and proteins responsible for muscle growth.

Many genes are likely to influence delay discounting; and some of Dr. Ahokhin's preliminary data suggest that these «impulsivity genes» may include genes coding for enzymes that synthesize the neurotransmitter serotonin and receptors where serotonin binds in the brain.

There are several reasons why nobody before Shatz had found genes coding for MHCI in normal neurons.

Shatz got a hint when she looked up ailments associated with mutations in genes coding for the human version of MHCI.

Then, 15 years ago, Shatz stumbled across genes coding for MHCI in fetal cat brains.

Mitochondria contain genes coding for proteins important in energy production.

Ginkgo's executives request the gene code for the oil from an outside provider.

Some proteins that these genes code for are known to be involved in stress and cell death.

In particular, he has focused on targeting the gene coding for flagellin protein b, or flaB, which has proved to be quite distinct from one genospecies to the next.

What's more, the gene codes for a chemical receptor involved in many brain functions, such as learning and memory, so the gene might also be involved in behavioral disorders.

The COMT gene codes for an enzyme that breaks down dopamine in the prefrontal cortex.

These are sequences made in the lab from RNA — the template used to produce the proteins that genes code for.

However, in the presentations, speakers for both teams said that two stretches of the gene code for so - called zinc fingers — protein structures that insert themselves into the grooves of DNA — suggesting that the encoded protein probably turns other genes on and off.

«For example, viral genes code for their own proteins that process their DNA,» said Gundlach.

His suspicionswas confirmed: the children had an identical defect — a missing single nucleic acid, called guanine — in the gene coding for leptin.

Another connects post-traumatic stress disorder to methylation of the gene coding for neurotrophic factor, a protein that regulates the growth of neurons in the brain.

(The DNA in genes code for mRNA, which, in turn, codes for proteins.)

The MDR1 gene codes for a protein that helps to extract drugs from cells.

The normal gene codes for a receptor for ethylene, a gaseous plant hormone that ripens fruit.

They sequenced the gene coding for the receptor in patients with either severe skin allergies or hyper - IgE syndrome, a rare condition in which the body produces too much IgE.

Juha Tapanainen of Oulu University Hospital in Oulu and colleagues at the University of Helsinki studied 15 brothers of infertile women who had mutations in the gene coding for the FSH receptor.

But knowing this, researchers note, does not necessarily explain what those genes do, given that many genes code for multiple forms of a protein, each of which could have a different role in a variety of biological processes.

A phage means bacteria eater and so they were very specific hosts, which is a very specific bacteria, and we like these viruses a lot because they only have a couple different genes and those genes code for a couple different proteins and so they are easy for us to manipulate in the lab.

These genes code for proteins involved in transporting small containers called vesicles throughout the healthy cell, but these proteins are often hijacked by viruses in order to move the virus through the cell.

These genes code for surface features on the toxin that trigger antibody production.

His trick was to insert the gene coding for CREB into a version of the herpesvirus that can infect neurons without spreading to nearby cells.

Transcription - factor genes code for proteins that regulate the activity of other genes and so affect an animal's ability to respond to its environment.

Sickle cell disease is a recessive genetic disorder caused by a single mutation in both copies of a gene coding for beta - globin, a protein that forms part of the oxygen - carrying molecule hemoglobin.

Xi's work also shows that even the genes that Rafflesia plants inherited from their own ancestors have appropriated the characteristics of the vines» genes; up to 30 percent of the corpse flowers» native genes code for proteins (the process that helps to determine physical traits) in a way that's more like the vines» than like its fellow Malpighiales».

«Genes code for the sequence of amino acids in proteins, and some are involved in the regulation of the expression of other genes,» he says.

Most resistance genes, in wheat and other plants, code for protein receptors located inside cells; the Stb6 gene codes for a receptor protein on the cell's surface.

Ten of those genes code for odor receptors, which researchers anticipate could become targets for future louse repellents.

All of these genes code for transcription factors, which are proteins that control the expression of other genes.

This gene codes for part of a pore in nerve cells called a potassium channel that is vital for transmitting nerve impulses to adjoining cells.