Sentences with phrase «genes encode proteins for»

And many genes encode proteins for molecular pumps that spit out foreign molecules — possibly including antibiotics — to detoxify the bacteria.

Not exact matches

When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.

The study results build on genetic and epigenetic basics, including that the blueprint for the human body is encoded in genes that direct the building of one or more proteins.

Some of these genes are involved in making the proteins encoded by the viral DNA and may make it easier for Mimivirus to co-opt host cell replication systems.

In 2004 the Nobel Prize in Physiology or Medicine went to Linda B. Buck and Richard Axel for their research showing that there is a huge family of genes that encode proteins called olfactory receptors.

However, in the presentations, speakers for both teams said that two stretches of the gene code for so - called zinc fingers — protein structures that insert themselves into the grooves of DNA — suggesting that the encoded protein probably turns other genes on and off.

The gene encodes a protein that is important for intracellular transportation.

He discovered a second clock gene, called timeless, that encodes another protein, TIM, which is required for a normal circadian rhythm.

How it hides: In a normal cell, genes encode instructions for surface proteins known as the major histocompatibility complex (MHC).

The actin gene encodes a structural protein that is essential for cell integrity.

A screen for mouse genes dependent on dHAND, a transcription factor implicated in neural crest development, identified Ufd1, which maps to human 22q11 and encodes a protein involved in degradation of ubiquitinated proteins.

Researchers would then have to pore through four or five databases for each one, trying to discern which genes (or the proteins they encode) have features most likely to affect the biology of the disorder — a painstaking task.

The gene encodes a pheromone - binding protein that may be crucial for recognizing fellow fire ants.

FBXL4 is a nuclear gene that encodes for a protein called F - Box and Leucine - Rich Repeat Proprotein called F - Box and Leucine - Rich Repeat ProteinProtein 4.

The researchers scoured the already deciphered mouse genome, looking for genes that might encode additional receptor proteins in its olfactory system, the sensory cells that connect the nose to the brain.

In the new work, Miranda M. Lim of Emory University and her colleagues inserted a gene that encodes for the vasopressin receptor protein directly into the brains of male meadow voles.

The researchers used bioinformatics to analyze gene mutations encoding for the APC / C protein complex.

The researchers were able to positively identify 15,419 genes that encode for specific proteins and speculatively identify another 15,396 putative genes.

Our genes can be thought of as packets of information written in sequences of DNA bases, which encode proteins that perform the functions necessary for life.

For the research, conducted in the insectary at the Johns Hopkins Malaria Research Institute in Baltimore, Dimopoulos and colleagues modified Anopheles gambiae mosquitoes by deleting the gene FREP1, which encodes an immune protein, fibrinogen - related protein 1.

Genes may carry information for building proteins, but a host of other factors, including the DNA between genes that doesn't encode proteins, tells them when to make their protGenes may carry information for building proteins, but a host of other factors, including the DNA between genes that doesn't encode proteins, tells them when to make their protgenes that doesn't encode proteins, tells them when to make their proteins.

For example, they found also accelerated adaptation for a gene encoding a lung surfactant protein (SFTPB), which may have been due to lung changes necessary for diviFor example, they found also accelerated adaptation for a gene encoding a lung surfactant protein (SFTPB), which may have been due to lung changes necessary for divifor a gene encoding a lung surfactant protein (SFTPB), which may have been due to lung changes necessary for divifor diving.

New discoveries about the rules governing how genes encode proteins have revealed nature's sophisticated «programming» for protecting life from catastrophic errors while accelerating evolution

EB results from mutations to any of several genes that encode proteins crucial for anchoring the outer layer of skin, the epidermis, to the tissue below.

Since the successful sequencing of the human genome, interest in the group of genes encoding proteins responsible for DNA remodeling has grown exponentially.

For example, they identified SNVs in genes encoding the collagen proteins that make up bone and cartilage, and in genes where other mutations have caused defects similar to Ata's, such as fewer - than - normal ribs or short stature.

According to first author Dr. Ariel Martinez, the study is an effort to address limitations of existing ADHD medications that don't work for all patients, and develop new medication targeting the protein encoded by the ADGRL3 gene.

The WFCD2 gene produces a «messenger RNA» that encodes for the HE4 protein, not only imparting an aggressiveness to the tumor, enabling it to grow quickly, but also conveying a resistance to chemotherapy drugs used to treat the tumor.

For each gene, the researchers compared the number of single letter mutations that alter the encoded protein versus silent mutations that have no effect.

Such is the case for a DNA letter in the gene that encodes the protein called tumour necrosis factor receptor 1 (TNFR1).

The researchers anticipate that the pigs could be a practical way to test treatments for HD, which is caused by a gene encoding a toxic protein that causes brain cells to die.

Although microRNAs do not code for proteins, they prevent specific genes from giving rise to the proteins they encode.

In flu surveillance, researchers look primarily for the genes encoding the virus's surface proteins, hemagglutinin and neuraminidase; if they sequence the so - called internal genes as well, they might detect new genes slipping into human virus strains in the run - up to a pandemic, they say.

To tease out what the LucA protein does, VanderVen's team created a novel LucA Mtb mutant, which revealed that the protein encoded by the gene LucA is an integral membrane protein required for fatty acid and cholesterol uptake in Mtb.

Dillman explained that the elusive instructions that provide this information to genes is found in the non-coding regions of DNA — stretches of DNA that do not encode information for protein synthesis.

The genes which encode these proteins therefore originate from the last common ancestor of mosses and flowering plants — the prehistoric plants which left the fresh water to dwell on rocks and thus laid the foundation for the development of all current ecosystems on the mainland.

Wolfram syndrome is caused by a mutation in the gene encoding a protein called wolframin, which resides in the membrane of the endoplasmic reticulum — another cellular compartment that functions as a manufacturing and packaging system and also acts as a reservoir for calcium ions.

They entered the sequence of the gene that encoded the transporters in a genome data bank and saw that it closely matched the genes for Rh proteins in humans.

And curious as to how widespread this phenomenon might be, the researchers looked for protein families with nearly identical members that are encoded by different genes and had significant variations in ribosome density across the family.

But after several questions about potential outcomes of such early research, Niakan did «wildly speculate» that, if certain genes are found to be particularly important for development, one eventual approach might be to check during IVF whether eggs were making the proteins encoded by those genes, and if not, then add them to culture media.

Rather than encoding for proteins themselves, HARs often help to regulate neighboring genes.

The researchers performed the same experiment, editing the γ - actin gene to encode the β - actin protein but were only able to change the coding sequence for three of the four amino acides.

Quantitative analyses of multiple cardiac phenotypes demonstrated essential structural, functional and developmental roles for these genes, including a subgroup encoding histone H3K4 modifying proteins.

Jeffrey Hall and Michael Rosbash of Brandeis University in Waltham, Massachusetts, and Michael Young of The Rockefeller University in New York City share the prize equally for their work on how several genes work together to control the basic circadian clock, encoding proteins that build up during the night and are broken down during the day.

Previously, Semenza's team generated a virus that carries the gene encoding an active form of the HIF - 1 protein, which turns on genes necessary for building new blood vessels.

The TOMM40 gene encodes a barrel - shaped protein in the outer membrane of mitochondria that forms a channel for molecules — including the precursor to amyloid — to enter.

This gene encodes for a Bcr - abl fusion protein.

The gene encodes a protein called plakophilin 2, which is crucial for the formation and proper functioning of the skin structure, suggesting an aberrant skin barrier as a potential risk factor for atopic dermatitis.

The maize divergent spindle - 1 (dv1) gene encodes a kinesin - 14A motor protein required for meiotic spindle pole organization.

Vaxwave ® is based on lymphocytic choriomeningitis virus (LCMV) and in this vector the gene encoding the LCMV envelope protein, normally responsible for virus entry into target cells, has been deleted and replaced with a target gene of interest.