Since the successful sequencing of the human genome, interest in the group of
genes encoding proteins responsible for DNA remodeling has grown exponentially.
Not exact matches
When similar analysis was performed on the db mice, it was found that the disrupted db
gene was
responsible for
encoding a
protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.
Vaxwave ® is based on lymphocytic choriomeningitis virus (LCMV) and in this vector the
gene encoding the LCMV envelope
protein, normally
responsible for virus entry into target cells, has been deleted and replaced with a target
gene of interest.
This
gene encodes for ABCA12, a metal binding
protein bearing a close functional relationship to ATP7B
responsible for Wilsons disease in humans.
This
gene encodes a
protein, P - glycoprotein that is
responsible for pumping many drugs and other toxins out of the brain.
The MDR1 (Multi-Drug Resistant)
gene encodes a
protein that is
responsible for ridding the brain of drugs.