Sentences with phrase «genes for brain function»

«We used the Allen Human Brain Atlas data to quantify how consistent the patterns of expression for various genes are across human brains, and to determine the importance of the most consistent and reproducible genes for brain function

Not exact matches

What's more, the gene codes for a chemical receptor involved in many brain functions, such as learning and memory, so the gene might also be involved in behavioral disorders.
Steve: And there's one of the researchers you quote in the article talks about, there may be genes that are not directly responsible for some aspect of brain function even at a biochemical cascade level; there might be a gene that is responsible for the width of the birth canal and that that could be associated with ultimately with intelligence.
For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell diseaFor his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disbrain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disbrain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBrain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBrain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disBRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell diseafor the first molecular disease: sickle cell disease.
Previous studies have looked mainly at genes causing atherosclerosis and genes affecting the function of platelets and clotting processes as risk factors for ischemic stroke (clot obstructing blood flow to the brain).
This epigenetic alteration of gene activity in brain cells that receive this neurotransmitter showed for the first time that dopamine deficiencies can affect a variety of behavioral and physiological functions regulated in the prefrontal cortex.
Some, for example, pointed to genes that expressed themselves in brain cells, or that involved immune function, a previously established connection.
For example, scientists have not been able to resolve what function the HTT gene serves normally, or how its mutation creates problems in the brain.
Identified eight highly potential target genes for binding by miR -124-3p, genes whose function is also reported to be critical in brain physiology during stress and MDD pathogenesis.
The study supports the importance of the serotonin which is specified and maintained by a specific gene, the Pet - 1 genefor normal functioning of the neurons, synapses and networks in the cortex, as well as proper development of brain circuitry.
«Everyone was focusing on genes expressed in the brain,» says Levitt, «but this gene is important for repair of the intestine and immune function.
... The FOXP2 gene has been around for a very long time, found in similar form in distantly related vertebrate species, and it may be important not only for brain development and function but also in other tissues.»
The gene - by - hormone interaction's effect on circuit function was found only with one of two versions of the gene that codes for BDNF (brain - derived neurotrophic factor), a chemical messenger operating in the circuit.
While the team doesn't know the function of those Neandertal gene variants, it began to search for their influence by examining brain tissue from the prefrontal cortex of 14 adults of European, African, and Asian descent, as well as 14 chimpanzees.
«A better understanding of the brain region and cell type - specific binding targets of Hnrnph1 will tell us more about the function of this gene and possibly identify new therapeutic strategies for minimizing risk and treating psychostimulant addiction — a disorder for which there is currently no FDA - approved drug,» explained corresponding author Camron Bryant, PhD, assistant professor of Pharmacology and Experimental Therapeutics & Psychiatry at BUSM.
An improved understanding of the biological background of musical aptitude can contribute new insights into, for instance, genes that affect normal brain functions, the interactions between genes and the environment and the significance of music as a form of therapy.
«What is evident is that the specific functioning of our brains, like our height and hair color, is strongly influenced by genes that were selected for among our ancestors.»
Fundraising Priorities Genomics Wolfe Chair in Gene Function Genomic Analysis of Vascular Neuroscience Barnett Chair for Medical Research Director Molecular Brain Research — Chair in Alzheimer's Research Molecular Brain Research — Concussion Research Molecular Brain Research — Disease Research Molecular Brain Research — Spinal Cord Research
Walsh and colleagues found that knocking out this gene disturbs the centriole's organization and function, suggesting an underlying biochemical mechanism for the brain deficits seen in the ferrets.
«This data allows classification of all human protein - coding genes into those coding for house - hold functions (present in all cells) and those that are tissue - specific genes with highly specialized expression in particular organs and tissues, such as kidney, liver, brain, heart, pancreas.
Dr. Coyle's Laboratory for Psychiatric and Molecular Neuroscience takes advantage of insights into recently identified genes that confer risk for schizophrenia and related disorders and translates them into genetic mouse models to determine how these mutations affect brain changes as well as function, neurochemistry, and behavior.
BDNF, a target gene of CREB, is reduced with age and in the AD brain [112] and is required for normal cognitive function [113].
For example, if a human HAR — one that turned up the human gene a lot — was injected into a chimpanzee brain cell, it would function the same way by turning up the activity of the chimp neuron a lot.
For example, Urban's group is using another publicly available resource, the Allen Brain Atlas, to find whether groups of neurons with similar electrical function have similar gene expression.
For example, you might be fast - tracked (thanks to the genes your parents gifted you) to be at risk of memory loss or heart disease, but you can change your genetics by following a diet and lifestyle activities that promote brain function and lower cardiovascular disease.
how environmental susceptibility genes — issues with detoxing toxins — make it difficult for your brain or gut to function properly
Actually I'm envious of you that you have this wonderful opportunity to provide one of the legacies you can give a child — a pristine anti-inflammatory pre-conception and in utero period of time where you are providing optimal gut - brain - fetus function, B vitamins / omega -3 for babbbbie's brain health and gene expression for future life and even your grandchildren.
Seizures occur when excessive activity goes beyond the normal threshold for brain function, many factors contribute to that level of activity, and therefore, mutations in numerous genes may collectively contribute to increased activity until that threshold is exceeded, resulting in epilepsy.
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