Sentences with phrase «genes for further»

This study is designed to determine the incidence of BCSL in the breed, to determine the mode of inheritance if a single gene is involved, and identify candidate genes for further investigation.

This study presents several candidate genes for further studies of the regeneration process.

Most simply, once these genes, or bits of DNA tied to the genes (known as markers), have been identified, molecular breeders can quickly target offspring inheriting the genes for further development, cutting breeding time and improving the crop's «genetic gain,» the generational improvements made to a crop, like increased height, by human selection.

The method identifies gene sets that show evidence for positive selection in comparison with matched controls, and thus highlights genes for further functional studies.

Not exact matches

We further understand that speciation will frequently not provide any clear morphological transition that would be evidenced in a fossil, i.e. in many instances, distinct species are only identifiable via phylogenetic analysis for the absence of gene flow.

For Dawkins, by far the most important aspect of biological nature is the ability of certain stretches of DNA («genes») to engender faithful copies of themselves, under conditions that prevail.

The principles that have emerged thus far are these: We should seek new knowledge of our genes (and we can say this without deciding whether the Human Genome Initiative is the wisest and most cost - effective way to do so) We should seek therapies for the genetic disorders that afflict many people.

The next step for him and his colleagues is to investigate further why the expression of the SHIP gene is altered in Crohn's disease.

The study, published online today in Science Translational Medicine, further points to a master switch for these gene sets as a potential target of future therapies.

For instance, people who have low cholesterol their entire lives — such as those born with a mutation in a gene called PCSK9 — suffer far fewer heart attacks than people who lower their cholesterol only later in life.

Despite the proliferation of GWAS, the associations found so far have largely failed to account for the known effects of genes on complex disease — the problem of «missing heritability.»

The deep look into the genes of transmitted H5N1 viruses also reveals the surprising degree to which the virus can mutate and genetically diversify in each infected host, a troubling trait for a pathogen that has so far infected 637 people, killing 378.

ESTs themselves are a far cry — and an enormous amount of painstaking scientific work distant — from the full - length genes necessary for the production of proteins.

The American cockroach has genes that code for more than 150 scent receptors and 500 taste receptors, the most found in any insect so far.

McDermott and his team have identified genes that will be further explored for their potential use in diagnosis and treatment in heart failure.

«We'd like to extend this further to examine for driver genes in other types of lung cancer, such as squamous cell lung cancer.»

Doyle is now tackling a far bigger network of genes in E. coli: the master network responsible for governing its metabolism.

But he is far more concerned about the potential for accidental release of gene - drive organisms by scientists, he says.

James Adjaye, a biologist at the Max Planck Institute for Molecular Genetics in Berlin, Germany, says that further work needs to be done before scientists can be sure that the genes found in the new work are actually indicate that an embryo will develop into a baby.

Parkinson contends that targeted gene replacement produces cells having specific genetic alterations far more effectively than the traditional technique for making transgenic animals, which entails injecting DNA into cell nuclei.

But whoever these people were, their descendants successfully spread far and wide, for their genes show up not only in Europeans but also in Native Americans, according to a talk by paleogeneticist Johannes Krause of the University of Tübingen in Germany, who spoke at a biomolecular archaeology meeting last week.

By following the DNA - transfer, scientists for the very first time showed an unknown mechanism called carry back in which pathogens were able to snatch genes from far - related bacteria via the carry back mechanism.

2002: Further forays in using retroviruses for gene therapy, however, bring tragedy.

Genetic tools still under construction, such as a haplotype map that will be used to discern genetic variation behind common diseases, could further accelerate the search for disease genes.

Additionally, genes for long organs were associated with genes for faster remating by females, which further increases competition among sperm and hence the advantage to males producing longer sperm.

Working with the Japanese National Institute of Agricultural Research's Rice Genome Programme in Tsukuba, Moore looked for genes shared between rice and wheat, and discovered that although wheat and rice diverged some 60 million years ago, the order of the genes in the two species is essentially the same, even though the genes are much farther apart in wheat.

Surani says he is cautious about drawing any further conclusion as to whether or not these have any functional significance for the health of future generations until they have discovered more about how these genes manage to evade reprogramming and why.

A transplant biopsy system that uses gene chips to read molecules is far safer and more effective than existing approaches used for heart transplant biopsies and is showing promising results for lung transplant biopsies, new University of Alberta - led research shows.

For the vast majority that never get that far, «you don't know how many genes were messed up,» observes Schöler.

Joint lead author Professor Manfred Kayser from Erasmus MC said: «Besides substantially increasing our understanding of human pigmentation genetics in general, finding these new hair colour genes is also important for further increasing the accuracy of hair colour prediction from DNA traces in future forensic applications, which can help to find unknown perpetrators of crime.»

Then the scientists cranked the zoom lenses on their metaphorical microscopes even further to focus on the specific genes in the bacteria that coded for production of the toxic protein.

With further development, CRISPR - Cas9 - based gene therapy may offer a new clinical strategy for CGD, and perhaps other blood disorders.

Further investigation, says Resar, showed that these unusual properties arise from the ability of HMGA1 to turn on several genes involved in the Wnt pathway, a network of proteins necessary for embryonic development and stem cell activity.

«The Isl1 gene further preserved the connections between hair cells and neurons, which is necessary for hearing,» said senior author Zheng - Yi Chen, D.Phil., Mass..

Subsequent work with immunologist Sebastian Fugmann of the National Institute on Aging in Baltimore, Maryland, and other colleagues added further evidence for the presence of Rag1 and Rag2 genes.

Their further analysis also provide evidence on the ancestral status of the Indian group, which holds great potential for introducing new alleles into the cultivated gene pool.

«Changes in genes» regulation — not in the DNA sequence of genes themselves — were the driving force behind successful metastases in our experiments, and, as far as we know, this is the first genomewide experimental evidence for this phenomenon.»

The researchers compared the DNA methylation profiles of thousands of genes in breast, colon, lung, and endometrial tissues, selecting one gene, TRIM29, for further analysis.

They further investigated the genomic basis of divergence among the cultivated populations for identifying genes controlling important traits.

«Certainly the concept of looking for genes that are involved in both in differentiation and in carcinogenesis is promising, and the novel list of breast - specific regulated genes we found may encourage further study in this direction.

So far, the Food and Drug Administration has not approved any human gene - therapy product for sale, but the day is coming.

Further investigation of the metabolic pathway that breaks down the fluorescent material revealed a gene, heme oxygenase - 1 (HO - 1), that may be responsible for the differences in fluorescence.

Currently, many researchers agree that 60 to 70 genes are related to the syndrome, but those genes account for no more than 20 percent of the cases — the best medicine can do so far.

While this link and preliminary hypothesis are intriguing, the researchers have not yet confirmed whether differences in the MMP2 gene are responsible for failed fillings, and will need to investigate this further.

However, since the novel genes that were identified, are known to lead to aging - associated diseases in humans, their further analysis seems to be promising for developing new approaches to understand and possibly cure these diseases and to contribute to a long life and healthy aging in humans — in a way, long - lived rodents do.

We hope that further research may identify why a faulty INPP5K gene causes these symptoms — and that information will help with the search for therapies in the future.»

The scientists also tagged another 12 gene variants as promising candidates for further study.

Although in rare cases mitochondrial genes may be transferred to the nucleus of a cell, she said the IU team found no evidence to suggest this is the case in V. scurruloideum, and that further investigation will be required to reveal the exact mechanism through which the species compensates for its missing genes.

Further analysis revealed that a single - letter change in the gene accounted for 46 per cent of the population's hair colour variation, with the blonde allele being recessive to the dark hair allele.

The researchers will now carry out further work to understand the fundamental mechanisms that make the interferon lambda genes so important for our ability to combat hepatitis caused by HCV.