If
the genes for a particular NAD precursor are not on, no amount of that precursor can help that cell make NAD.
For example, Mary - Kate and Ashley might have identical
genes for a particular health problem, but only Mary - Kates» environment will flip the gene to the «on» position.
Until now the basic approach has been to isolate
genes for particular rotavirus proteins, clone them and insert them into animal cells.
And although the rest of Genghis Khan's genome has certainly, if Zerjal and Tyler - Smith are right, made an outsize contribution to the Central Asian gene pool, it has been chopped to bits and mixed in so thoroughly over the centuries by genetic recombination that no one today is likely to have his whole suite of
genes for any particular trait.
Steve: So you might have
a gene for a particular brain receptor or, I think what you talk about in the article is not actually the structure of the receptor molecule, but the amount of receptors that you actually produce?
«In the past, we thought we could define all the silk genes in one species, that there would be a handful, and we could say, «This is
the gene for a particular kind of silk,»» Hayashi says.
Chromosomes occur in pairs, each of which has
a gene for a particular trait at the same location.
Not exact matches
Recently a team of its researchers combed through this data, searching the the genomes of 89,283 people
for correlations between
particular genes and a person's self - reported status as a lark or night owl.
«So in many cases,» says Doug Gurian - Sherman, a plant pathologist and director of sustainable agriculture at the Center
for Food Safety, «the
particular genes used will only work well in certain genetic backgrounds and environments.»
For instance, one admits that in much of evolution (probably all above the bacteria), evolutionary changes involve enormous numbers of genes, rather than a selection of one or two particular genes (although that occurs in a few instances, possibly, for instance, in industrial melanis
For instance, one admits that in much of evolution (probably all above the bacteria), evolutionary changes involve enormous numbers of
genes, rather than a selection of one or two
particular genes (although that occurs in a few instances, possibly,
for instance, in industrial melanis
for instance, in industrial melanism).
«Some people are protected from the effects of sleep deprivation by this
particular gene variation but,
for most of us, sleep loss does something to the brain that simply prevents us from switching gears when circumstances change.»
For Molly Schumer, a postdoctoral fellow in genetics and evolutionary biology at Harvard Medical School, the fellowship will help fund her research on how evolutionary forces affect our
genes, focusing in
particular on a persistent trait that can cause melanoma in swordtail fish.
This
particular founder was born missing the letters A (
for adenine) and G (guanine) from the DNA chain at the 185 site on one copy of his or her BRCA1
gene.
The authors note that DRD4 in
particular, a dopamine receptor
gene, has been extensively studied
for its involvement in novelty - seeking behavior in primates, fish and birds.
In
particular, he has focused on targeting the
gene coding
for flagellin protein b, or flaB, which has proved to be quite distinct from one genospecies to the next.
These allusions to the past aren't surprising considering how drastically the clinical trial changed
gene therapy and, in particular, the career of James M. Wilson, the medical geneticist who headed Penn's Institute for Human Gene Therapy, where the test took pl
gene therapy and, in
particular, the career of James M. Wilson, the medical geneticist who headed Penn's Institute
for Human
Gene Therapy, where the test took pl
Gene Therapy, where the test took place.
In this way the binding of the DNA to the corresponding nucleosome is changed so that the DNA
for example becomes accessible
for transcription enzymes and activates a
particular gene.
This unexpected result suggests that mutations in NPM1 behave as gatekeepers
for this cancer; once a mutation in this
gene occurs in a cell with
particular previously accumulated pre-leukaemic mutations, the disease progresses rapidly to become leukemia.
We used the LD signal strength as a guide to find our way to the true risk
gene — the
particular variant that actually caused the increased risk
for lupus.»
In
particular,
genes account
for only 1.2 percent of the genome's three billion bases.
What turns out [is] that scientists are having [a] really, really hard time finding them, and what that tell [s] us is that there are these
genes that influence intelligence but each
particular gene is responsible
for a tiny, tiny amount of variation — like a fraction of 1 percent.
Currently, you can cheaply search
for one
particular gene or disease in great detail or you can search your whole genome in poor detail.
The methyl group works like a placeholder in a cookbook, attaching to the DNA within each cell to select only those recipes — er,
genes — necessary
for that
particular cell's proteins.
For example, changes in certain
genes could indicate that his cancer was more likely to respond to a
particular drug, while other mutations might predict little benefit from a specific therapy.
While several studies in the intervening years have investigated whether
particular genes were responsible
for modifying HD onset, this is the first to employ genome - wide association (GWA) analysis, which scans an individual's whole genome to identify chromosomal regions containing variants that are associated with the disease traits that are being studied.
For any particular cell, such as a skin or brain cell, much of this genetic information is extraneous and must be packed away to allow sufficient space and resources for more important gen
For any
particular cell, such as a skin or brain cell, much of this genetic information is extraneous and must be packed away to allow sufficient space and resources
for more important gen
for more important
genes.
The same could be said
for the mechanisms that determine which
genes or suites of
genes are turned on or off at
particular times and places.
This capability allows a scientist,
for example, to instruct a software applet to go find information about a
particular gene — but only information that comes with a free license.
One species, Glycine tomentella, was of
particular interest because it has
genes for resistance to soybean rust and to soybean cyst nematode, he said.
The latest findings offer new focus points into how these
genes and others may be modified to fine - tune a wheat variety
for a
particular environment, which will result in less crop and food loss due to changing environment.
Over the longer term, the identification of the coffee tree genome sequence opens up new possibilities
for varietal improvement, knowledge of the specific functions of the
genes (in
particular those specific to coffee trees), the possibility of transferring results to other species, and refining diagnostic tools
for the function of the plant.
But some of the babies did not show this normal decrease in vagal tone during distressing periods; the researchers found that these infants who lacked an effective response at ages three and six months shared a
particular variant of the DRD2
gene, which regulates receptors
for the neurotransmitter dopamine.
Exposure to small amounts of lead may contribute to ADHD symptoms in children who have a
particular gene mutation, according to new research published in Psychological Science, a journal of the Association
for Psychological Science.
Of
particular interest are the emerging techniques
for genomics and proteomics, which allow profiles of
gene expression and protein synthesis to be produced and comparisons to be made between normal and abnormal cells, as well as between cells before and after exposure to medicines or toxic chemicals.
The researchers have studied analyses of the genetic material of viruses found in newly infected people and, in
particular, the
gene env, which codes
for the protein envelope or «coat» around the virus.
By identifying the
genes in any given taste cell, scientists can pinpoint the unique molecular components needed
for that cell to carry out its
particular function.
«We knew that Smchd1 was an epigenetic suppressor — a factor that switches off
genes that are unnecessary
for that
particular cells» function — but we were in the dark about where and how it was acting on the DNA.»
In
particular, this region of the
gene might serve as a landing place
for cellular machinery that binds to the DNA and reads it, Nikolova said.
«The BDNF
gene has previously been linked to obesity, and scientists have been working
for several years to understand how changes in this
particular gene may predispose people to obesity,» said Jack A. Yanovski, M.D., Ph.D., one of the study authors and an investigator at NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
While the genetic code carried in our DNA provides instructions
for cells to manufacture specific proteins, it is a second code that determines which
genes are in fact activated in
particular cell types.
Carrying a
particular version of the
gene for apolipoprotein E (APOE) is the major known genetic risk factor
for the sporadic, late - onset form of Alzheimer's disease, but exactly how that variant confers increased risk has been controversial among researchers.
The researchers found that individuals carrying a
particular genetic variant had shorter telomeres — meaning less padding
for those fragile
genes.
Laurent Keller at the University of Lausanne in Switzerland and Kenneth Ross at the University of Georgia, Athens, were scanning the
genes of various populations of fire ants (Solenopsis invicta) when they noticed something strange: Queen ants who had their own colonies carried two copies of the dominant variety of a
particular gene — they were homozygous
for the variety, that is — while those who shared a nest with other queens were heterozygous, carrying only one copy.
Of
particular interest was the group of
genes responsible
for temperature sensation, which also play roles in hair growth and fat storage.
For example, some people have a
particular variant of the ADH1B
gene that causes an amino acid change in this enzyme, which leads to faster enzyme activity so individuals with this variant metabolize alcohol more rapidly which means that acetaldehyde levels are temporarily increased.
A
particular form of the
gene known as TPCN2,
for example, bestows brown hair in modern humans; any other form means hair that's another color.
One study even identified two
genes in which
particular variants can slow the onset of AIDS, demonstrating the potential of this approach
for understanding why people vary in their susceptibility to infectious diseases.
«Clearly, the conclusions
for this
particular gene need to be reconsidered,» says Jaenisch, who is also a professor of biology at MIT.
Analyzing large numbers of cells, each with slight differences in their DNA,
for their ability to carry out a behavior or survive a drug treatment can reveal the importance of
particular genes, or sections of
genes, in those abilities.
For each set of organisms, they used differences in the number of mutations in certain
genes to determine where each organism sat in its
particular group's tree.