Sentences with phrase «genes for proteins called»

Sometime in the past 1,500 to 20,000 years, Y. pestis lost a set of genes for proteins called adhesins, which bind the bacteria to intestinal walls.

Two variants stood out, the most significant associated with the gene for GDF15 and the second with a gene for a protein called IGFBP7.

To boost the staying power of the engineered T cells, the UPenn group wants to use CRISPR to disrupt the gene for a protein called PD - 1.

The team knocked out the gene for a protein called nuclear receptor corepressor 1 (NCoR1) in the muscles of mice.

In a 2007 paper published in The Journal of Allergy and Clinical Immunology Poland and his colleagues reported that people who have mutations in a gene for a protein called SLAM produce 70 percent fewer antibodies after live measles inoculation than people without the mutation.

The newly fingered SNP lies in a gene for a protein called LINGO1 that is present only in the brain and spinal cord — a distribution consistent with a role in neurological disorders, says neurologist Dietrich Haubenberger of the Medical University of Vienna in Austria, one of the study's authors.

Team members Julie Nixon and John Samuelson of Harvard University found the 35 - base intron in the middle of the gene for a protein called ferredoxin.

«These kids accumulate repeats in a gene for a protein called frataxin that mitochondria, the cell's powerhouse, need to process energy.

Caused by a mutation in the gene for a protein called huntingtin, the disease damages brain cells so that people with Huntington's progressively lose their ability to walk, talk, think and reason.

Not exact matches

Patients that have a defective gene called RPE65 — which is responsible for producing a protein that makes light receptors in the eye — suffer from leber congenital amaurosis and retinitis pigmentosa, yet now have hope.

The OAR proposal uses a variation of therapeutic cloning called altered nuclear transfer (ANT) in which the nucleus of a donor cell (a skin cell, for example), containing the 30,000 genes of the genetic code, is altered in such a way that it produces an epigenetic factor, a protein called nanog.

Certain DNA segments «code for» or build proteins, and those segments are indeed called genes.

When looking for genes that might play important roles in the metabolism of healthy and cancerous liver cells, Wang and his colleagues became interested in a gene called SLC13A5, which produces a protein that transports citrate into cells.

This pathogen has an inner protein core called HBc, and something intriguing happens when the gene for HBc is inserted into the bacterium Escherichia coli.

In 2004 the Nobel Prize in Physiology or Medicine went to Linda B. Buck and Richard Axel for their research showing that there is a huge family of genes that encode proteins called olfactory receptors.

However, in the presentations, speakers for both teams said that two stretches of the gene code for so - called zinc fingers — protein structures that insert themselves into the grooves of DNA — suggesting that the encoded protein probably turns other genes on and off.

Recently he found that eight of the youngsters have a defect in a gene that codes for a receptor protein called melanocortin - 4, known to regulate eating in mice.

Researchers know that cells chop single genes into shorter pieces called exons, which they mix and match into one transcript for creating a protein.

He discovered a second clock gene, called timeless, that encodes another protein, TIM, which is required for a normal circadian rhythm.

The trio also isolated the gene for this protein, called channelrhodopsin - 2 (ChR2).

Not long after the HD gene was isolated, studies led by MacDonald, also a co-author of the current investigation, found that a variation in the number of CAG trinucleotide repeats within the HD gene, which codes for a protein called huntingtin, is the primary determinant of the age at which HD symptoms appear, with a greater number of CAG repeats associated with an earlier symptom onset.

The approach is already routine for some cancer patients, such as women and men with breast cancer tumors that have high levels of a protein called HER2, or lung cancer tumors with mutations in the EGFR gene.

In all CS cases, said Morrow who treats autism patients at the E. P. Bradley Hospital in East Providence, boys have a mutation on the SLC9A6 gene on the X chromosome that disables production of a protein called NHE6 that is important for neurological development.

These genes code for proteins involved in transporting small containers called vesicles throughout the healthy cell, but these proteins are often hijacked by viruses in order to move the virus through the cell.

They found genes for five new receptors, all of which belong to a known family of proteins called formyl peptide receptors (FPRs).

If cells were infected with an influenza A mutant lacking NS1, they proceeded to produce large number of the molecular complexes required for RNAi, which include a protein called Argonaute that slices through the target gene.

Like most genes, the RNA for the dystrophin protein undergoes a process called splicing, in which stretches of so - called «junk» are clipped out.

The new locus they have identified is near a cluster of genes which code for proteins called «glycophorins» that are involved in the malaria parasite's invasion of red blood cells.

FBXL4 is a nuclear gene that encodes for a protein called F - Box and Leucine - Rich Repeat Proprotein called F - Box and Leucine - Rich Repeat ProteinProtein 4.

Additional experiments showed that the protein produced by HMGA1 activates another gene called Sox9, which is directly responsible for turning stem cells into Paneth cells.

When they inserted those genes into crop genomes, through a technique called recombinant DNA, the plants were able to produce the protein for bug resistance on their own, eliminating the need to spray insecticide.

The three Toxoplasma types have the gene for this protein, called MAF1, but only type I and III make the protein, the researchers found.

Some of the genes involved help regulate the flow of ions in and out of the cells, particularly nerve cells; others code for so - called heat shock proteins that are typically induced during stress.

VirSorter also «fished» for sequences by looking for genes known to help produce a protein shell that all viruses have, called a capsid.

The repeated mutation that causes Huntington's disease lies within a gene that codes for a protein called huntingtin.

They looked for proteins that associate with the FAL1 RNA and identified a protein called BMI1, a member of a gene regulatory complex called PRC1.

But rather than delivering the entire gene for the clotting - factor proteins to cells, as most gene therapies do, the researchers used the viruses to engineer immune - regulating B cells to express a fragment of the clotting factor fused to an immune molecule called an immunoglobulin.

The gene, called gyrase B, codes for a variable subunit of the DNA gyrase protein, which helps DNA coil and uncoil.

The researchers then tested the particles» ability to shut off the gene for a blood clotting protein called Factor VII, which is produced in the liver by cells called hepatocytes.

Researchers have known for several years that when fruit fly larvae metamorphose into adults, a gene called fringe produces a protein that tells certain cells to become the wing margin, the leading edge of a developing wing.

In 1991, Robertson and her colleagues reported an unusual discovery involving a gene called Igf2, which is responsible for producing a protein known as insulin - like growth factor II (IGF - 2), important for the growth of many kinds of tissue in the developing fetus.

One such example, Thomas said, are modifications of specialized proteins called histones, which are responsible for packaging DNA in the cell nucleus and influencing how genes are regulated.

In clinical trials already underway, for example, researchers have used an older gene - editing technique, enzymes call zinc finger nucleases, in immune cells to deactivate the gene for CCR5, a surface protein that HIV latches onto in order to infect cells.

The disease arises from a mutation in genes that normally make a protein, called myotubularin, essential for proper muscle function.

Scientists at NYU Langone Medical Center and New York University have demonstrated that a specialized DNA - binding protein called CTCF is essential for the precise expression of genes that control the body plan of a developing embryo.

In addition to adding the genes for glucaric acid production, the researchers engineered each cell to produce a protein that synthesizes a small molecule called AHL.

To find out how, he turned to an engineered strain of mice lacking a gene for what was then a mysterious protein called osteocalcin, which is produced by osteoblasts.

Both De Luca and Marinkovich's teams are exploring a similar gene therapy for another major form of the disease, called dystrophic EB, caused by a different genetic error affecting a larger protein.

Wondering why the third protein, an enzyme called p66, was not, despite being very similar to the other two, Pelicci's team knocked out the piece of the gene that enabled it to code for p66, in order to make mice and mouse embryonic cells that lacked p66.

One of the genes involved in feeding the big brain, called SLC2A1, builds a protein for transporting glucose from blood vessels into cells.