Sentences with phrase «genes for receptor»

In contrast, among Old World (African) primates such as humans, the two different X chromosome genes duplicated so that each X chromosome now carries the genes for both receptor types, giving both males and females trichromatic color vision.
The organism has a huge suite of genes for receptor and signaling proteins, far more than in most similar organisms.
Genes for a receptor that helps transmit nerve signals in animals have been found in, of all things, plants.
That means that the approach that worked so well for finding the sweet receptor — identifying a likely gene for the receptor, destroying it in mouse embryos, and proving that the resulting mice are unable to taste sweetness — will not work in the search for the salt receptor.
Aedes has already been shown to possess extra genes for receptors that detect odors, for proteins that help it purge pesticides from its system, and for controlling the makeup of its outer shell.
A variant in the gene for this receptor previously had been linked to asthma in genetic studies, but the potential role of the receptor, called CDHR3, in asthma was unknown.
They cultured the cells in the lab for a day, then exposed them for 3 days to a virus which contained the normal gene for the receptor.
They went on to find new genes for receptors sensitive to different wavelengths of light.
The mouse T cells developed receptors for this clearly suspicious invader and the genes for the receptors is what He later put on human T cells.

Not exact matches

Caplan said the best bet for super powers through gene editing would be greater muscle strength, better memory, quicker reaction times, better night vision, and turning up receptors to experience things like alcohol, drugs, and sex more intensely.
Patients that have a defective gene called RPE65 — which is responsible for producing a protein that makes light receptors in the eye — suffer from leber congenital amaurosis and retinitis pigmentosa, yet now have hope.
Just before Election Day — surely not a coincidence — scientists report an association between liberal political views and DRD4, a gene that produces a receptor for the neurotransmitter dopamine.He....
UT Southwestern biochemists studying mouse models found that the two proteins − steroid receptor coactivators 1 and 2 (SRC - 1 and SRC - 2)-- control genes for pulmonary surfactant components that promote the initiation of labor.
When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.
We identified some specific resistance genes that code for receptor - like proteis (RLPs) and described how they operated against the pathogens.
The authors note that DRD4 in particular, a dopamine receptor gene, has been extensively studied for its involvement in novelty - seeking behavior in primates, fish and birds.
What's more, the gene codes for a chemical receptor involved in many brain functions, such as learning and memory, so the gene might also be involved in behavioral disorders.
To see if any other receptors existed, Rodriguez's team took tissue from the vomeronasal organ — a pheromone - detecting sense organ found in the nasal cavity of mice, and some other mammals — and searched for genes expressing other possible smell receptors.
Using gene mapping techniques, the researchers zeroed in on a mutation in the gene for hypocretin receptor 2.
«We found that interbreeding with archaic humans — the Neanderthals and Denisovans — has influenced the genetic diversity in present - day genomes at three innate immunity genes belonging to the human Toll - like - receptor family,» says Janet Kelso of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.
Steve: So you might have a gene for a particular brain receptor or, I think what you talk about in the article is not actually the structure of the receptor molecule, but the amount of receptors that you actually produce?
Since genes for the T - cell receptor beta chain were previously shown to be on mouse chromosome 6, all three of the Ig - like multigene families expressed and rearranged in T cells are located on different chromosomes, just as are the B - cell multigene families for the Ig heavy chain, and the Ig kappa and lambda light chains.
«Fibroblast growth factor receptor inhibitors are new therapies being developed in clinical trials for patients whose cancer cells have genetic alterations in this family of genes,» says Roychowdhury, a member of the OSUCCC — James Translational Therapeutics Program.
In 2004 the Nobel Prize in Physiology or Medicine went to Linda B. Buck and Richard Axel for their research showing that there is a huge family of genes that encode proteins called olfactory receptors.
Recently he found that eight of the youngsters have a defect in a gene that codes for a receptor protein called melanocortin - 4, known to regulate eating in mice.
The «business end» of the gene — which codes for the actual receptor — was fairly constant in humans, suggesting that individual differences exist within the gene's regulatory areas.
The American cockroach has genes that code for more than 150 scent receptors and 500 taste receptors, the most found in any insect so far.
One key gene encodes the making of a receptor called TREM2, a docking site for molecules on the surface of microglia and other innate immune cells.
Destroy a gene for a common sodium receptor and your mice won't survive long enough to be born.
Those animals with more active forms of the gene had higher numbers of mu receptors in their tissues — and higher tolerances for pain.
In the pups of inattentive mothers, they found that genes regulating the production of glucocorticoid receptors, which regulate sensitivity to stress hormones, were highly methylated; in the pups of conscientious moms, the genes for the glucocorticoid receptors were rarely methylated.
The answer may lie in the gene that codes for the umami taste receptor.
Perhaps most significantly, in a study led by Frances Champagne — then a graduate student in Meaney's lab, now an associate professor with her own lab at Columbia University in New York — they found that inattentive mothering in rodents causes methylation of the genes for estrogen receptors in the brain.
Research on prairie voles suggests that it's possible to predict which voles will exhibit pair - bonding behavior just by looking for those expressing the gene for AVPR1a, a specific vasopressin receptor.
The normal gene codes for a receptor for ethylene, a gaseous plant hormone that ripens fruit.
The team spliced a nonfunctional gene for the ethylene receptor, taken from a common laboratory plant called Arabidopsis, into petunias.
The second gene, TNFRSF6B, encodes a receptor related to those that bind tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD as well as in patients with other autoimmune disorders such as rheumatoid arthritis and psoriasis.
They sequenced the gene coding for the receptor in patients with either severe skin allergies or hyper - IgE syndrome, a rare condition in which the body produces too much IgE.
Juha Tapanainen of Oulu University Hospital in Oulu and colleagues at the University of Helsinki studied 15 brothers of infertile women who had mutations in the gene coding for the FSH receptor.
The mutation, in a gene called HTR2B, prevents production of the serotonin 2B receptor, a key docking point in brain cells for the neurotransmitter serotonin.
The researchers mated female mice unable to make the receptor for type I interferons to males with one copy of the gene needed to make the receptor.
Although the men with the mutant genes produced FSH, support cells for the sperm - producing cells in their testes lacked the receptors for the hormone.
Lindstrom and his colleagues inserted genes for human nicotinic receptors into frog eggs and incubated them with levels of nicotine similar to those found in the blood of a human smoker.
The most common, found in nearly two - thirds of the samples, were abnormalities in genes responsible for the androgen receptor — a cell structure that sends growth signals in response to the male hormone androgen.
Zwiebel and colleagues scanned the mosquito genome looking for genes similar to those that generate fruit fly odorant receptors, proteins that project from nerve cells and initiate a biochemical cascade when they encounter certain molecules in the air.
They found genes for five new receptors, all of which belong to a known family of proteins called formyl peptide receptors (FPRs).
Sleep - wake cycles and our understanding of narcolepsy have been advanced by the discovery of orphan receptors, as well as their associated ligand peptide hormones and the genes that code for them.
Many genes are likely to influence delay discounting; and some of Dr. Ahokhin's preliminary data suggest that these «impulsivity genes» may include genes coding for enzymes that synthesize the neurotransmitter serotonin and receptors where serotonin binds in the brain.
The researchers scoured the already deciphered mouse genome, looking for genes that might encode additional receptor proteins in its olfactory system, the sensory cells that connect the nose to the brain.
The former target, say, using gene editing techniques to inactivate HIV receptors and achieve resistance of blood cells to the virus (which Sangamo BioSciences is working on in clincial trials) is different than helping parents who both carry genes for Huntington's Disease to have a child that is free of the disease (a change to the genome that would be passed on to future generations and would likely not be very commonly needed).
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