Sentences with phrase «genes for schizophrenia»

For example, researchers are looking for specific genes for schizophrenia in Finland, HIV in Gabon, obesity in Micronesia and alcoholism in Iceland.

During these years, my team discovered several promising candidate genes for schizophrenia and smoking addiction.

Dr. Malaspina continued «I think three of the interesting factors that have been linked to the risk of schizophrenia are severe stress in a stress - sensitive person who has underlying genes for schizophrenia, traumatic brain injury in those with underlying genes for schizophrenia, and, very importantly, cannabis exposure in early adolescence.»

It is neither nature nor nurture alone that is responsible for brain chemistry and development; rather it is the interaction between both genes and environment that is responsible for the brain development of an individual Research suggests that if a person has the genes for schizophrenia, but doesn't experience the environmental factors necessary to «trigger» or express these genes then the likelihood is low that they will develop schizophrenia.

Harris cited other examples of concern — a review of 100 studies in the field of psychology in which the findings in only about a third of the studies were reproducible; an effort by scientists at Bayer, another large drug company, that managed to reproduce the findings of only one - quarter of the studies under review; a just - published review of 25 historical candidate genes for schizophrenia which found no evidence that the candidate genes are more associated with the disease than other genes.

A gene for schizophrenia has not yet been mapped.

Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia.

Not exact matches

In addition to the new work's potential for RS, there is speculation that it could pave the way to treatments for other neurological disorders, such as learning disabilities, schizophrenia, autism and newborn encephalopathy as well as some mental retardation that has also been linked to the Mecp2 gene.

The researchers identified for the first time master genes that they believe control hundreds of other genes which are linked to Alzheimer's disease, Parkinson's disease, post-traumatic stress disorder, stroke, attention deficit hyperactivity disorder, autism, depression, schizophrenia and other disorders.

Working with this hypothesis, the researchers conducted a statistical analysis of the CX3CR1 gene in over 7000 schizophrenia and autism patients and healthy subjects, finding one mutant candidate, a single amino acid switch from alanine to threonine, as a candidate marker for prediction.

Seven genes for intelligence are also associated with schizophrenia; nine genes also with body mass index, and four genes were also associated with obesity.

A new multi-institutional study by Japanese researchers shows a potential rare gene mutation that could act as a predictor for two neurodevelopmental disorders, schizophrenia and autism.

In general, more than 70 percent of schizophrenia cases are sporadic versus familial — so many patients have variants of influential genes that have occurred in them for the first time.

Dr Antonio Pardiñas, first author of the study, said: «We show for the first time that genetic variants that do not severely impact gene function, but presumably have a more subtle impact on these critical genes, increase risk for developing schizophrenia.»

We did not find any evidence for a so - called «positive selection» but instead found that many gene variants linked to schizophrenia reside in regions of the genome in which natural selection is not very effective in the first place.

The largest of its kind, the study examined genetic data in 100,000 individuals including 40,000 people with a diagnosis of schizophrenia and also found that some of the genes identified as increasing risk for schizophrenia have previously been associated with other neurodevelopmental disorders, including intellectual disability and autism spectrum disorders.

Understanding the function of this gene — described this month in journal Molecular Psychiatry — could lead to more effective treatments for schizophrenia.

Study shows memories formed by the same gene - silencing tool used in embryonic development; a finding could set the stage for new therapies for schizophrenia

To test this hypothesis, an international team led by evolutionary biologist Philipp Khaitovich of the Shanghai Institutes for Biological Sciences in China and the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, set out to see how many brain - related genes implicated in schizophrenia underwent positive natural selection since humans and chimpanzees diverged from a common ancestor between 5 million and 7 million years ago.

They found that dramatically reducing the amount of protein expressed by TMEM108, a gene already associated with schizophrenia, results in fewer, smaller spines, which work like communication fingers for neurons, said neuroscientist Dr. Lin Mei.

«For instance, the gene YWHAZ, involved in neuronal migration and plasticity, is associated with other diseases such as schizophrenia,» explains Cormand.

Hugh Gurling of University College London tested people with schizophrenia for mutations in the pericentriolar material 1 (PCM1) gene.

Basel scientists have now identified a network of genes that controls fundamental properties of neurons and is important for human brain activity, memory and the development of schizophrenia.

Jeremy Hall of the University of Edinburgh, UK, found that a mutation in the gene that codes for the protein is linked to a higher risk of schizophrenia.

An alteration in the neuregulin - 1 gene — a single change in one letter of the DNA code for the protein — has been found in families with schizophrenia and linked to late - onset Alzheimer's disease with psychosis.

Researchers checked the genomes of 150 patients with schizophrenia and those of 268 healthy people, looking for large duplications and deletions of genetic material that disrupted the function of a gene.

«Repairing the brain: Two genes unlock potential for treatment of schizophrenia.»

Additionally, in demonstrating the usefulness of the new method, the discovery paves the way for faster progress toward identifying genes involved in complex mental illnesses such as autism and schizophrenia — as well as potential drugs for such conditions.

The ability to manipulate specific genes within these hippocampal chandelier cells may allow for more meticulous studies of several diseases, including epilepsy and schizophrenia, in which these neurons have been implicated.

A drug prescribed to many patients with schizophrenia or bipolar disorder may decrease negative symptoms for people with a certain variant of the COMT gene, suggests a new study from researchers at Columbia University Medical Center (CUMC).

For this study, the team, which also included Bernard Crespi, an evolutionary biology professor at Simon Fraser University in British Columbia, and East Carolina University evolution professor Kyle Summers, focused on 76 gene variations most strongly related to schizophrenia.

Researchers found that the gene XIST, which is responsible for inactivating one of the two copies of the X chromosome in cells that store genetic material, works overtime in female patients with mental illnesses, such as bipolar disorder, major depression and schizophrenia.

Gene studies have failed to provide simple explanations for ailments like schizophrenia and MS. Torrey's theory may explain why.

For instance, says Korenberg, the data could help scientists to link genes that seem important in certain mental disorders, such as schizophrenia or autism, to specific brain - wiring abnormalities.

Amongst others, Dr. Sonntag's work has contributed to developing a cell therapy for Parkinson's disease (PD), and to understanding a role of dysregulated gene and miRNA expression networks in PD and schizophrenia, or dopaminergic and adrenergic receptors in hedonic and impulsive behavior.

Finally, recent large - scale human genetic studies have implicated mutations in the NMDAR itself and serine racemase, as well as many genes associated with the postsynaptic density, with increased risk for schizophrenia.

If you have the genes, but don't experience the environmental «triggers» for schizophrenia - then evidence suggests that you'll never get schizophrenia.

Isolating a gene that is «associated» with schizophrenia or is a «risk factor» for schizophrenia doesn't necessarily have a doggone thing to do with preventing it or curing it.

Dr. Coyle's Laboratory for Psychiatric and Molecular Neuroscience takes advantage of insights into recently identified genes that confer risk for schizophrenia and related disorders and translates them into genetic mouse models to determine how these mutations affect brain changes as well as function, neurochemistry, and behavior.

Thousands of years after the last interbreeding, Neanderthal DNA still influences height and risks for conditions like schizophrenia and lupus by affecting how genes are turned on and off.

Now researchers at UC San Francisco have taken the first step toward a comprehensive atlas of gene expression in cells across the developing human brain, making available new insights into how specific cells and gene networks contribute to building this most complex of organs, and serving as a resource for researchers around the world to study the interplay between these genetic programs and neurodevelopmental disorders such as autism, intellectual disability and schizophrenia.

The Neanderthal version of a gene known as ADAMTSL3, for instance, is tied to height and schizophrenia.

According to Andreassen, the study's senior author, some think of schizophrenia as a «side effect» arising from advantageous variants in genes that are related to the development of human traits, such as cognitive and language skills, that may have increased risks for developing psychoses.

Although the exact cause of schizophrenia remains unknown, experts do agree that schizophrenia develops as a result of interplay between biological predisposition (for example, inheriting certain genes) and the kind of environment you are exposed to.

«Our results suggest that neuropsychiatric CNVs can be used as an instrument for further study of the cognitive abnormalities that characterize schizophrenia, because whether or not an individual develops this disease is likely related to the expression of these genes,» said Stefansson.

Problems with another gene, which codes for catechol - O - methyl transferase (COMT), could interfere with the metabolism of dopamine, increase the risk of schizophrenia and affect the frequency of manic cycles in bipolar disease.

A protein called disrupted - in - schizophrenia 1, encoded by the DISC1 gene, has been established as a genetic risk factor for a wide array of psychiatric disorders, including schizophrenia, bipolar disorder, major depression,...

I think that the cure for schizophrenia can be found in a single gene.

The researchers suggested that men and women who are thought to be at higher risk of developing schizophrenia might be diagnosed through the use of a genetic test for this overactive form of the dopamine receptor gene.

The NIMH reported today that Clues about how a suspect version of a gene may slightly increase risk for schizophrenia are emerging from a brain imaging study by the National Institute of Mental Health (NIMH).