MetG is a considered as conserved
gene finding so many HGT event in this gene indicate that horizontal gene transfer is very common in this gene.
Most recently by adding a new Multigen Labradoodle Stud «Apollo» and with Apollo we've also been able to add the Red and Blue Merle coloring
gene found so desirable in our Aussiedoodles, now it can also be found in our popular Multigen Labradoodle bloodline as well.
Not exact matches
In an effort to
find answers to some of those questions, researchers recently identified the
so - called «wanderlust
gene» (DRD4 - 7R, to be exact), which is present in about 20 percent of humans.
But the vitamin A content was still low,
so they turned to a
gene found in corn, which increased the amount of vitamin A 23 times.
The probability of a randomly selected mutation in a randomly selected
gene having precisely that effect is quite low,
so just as with the stones in the field, a positive
finding is more likely than not to be spurious — unless the experiment is unbelievably successful at sorting the wheat from the chaff.
Suppose it could be shown from past letters that my father met my mother because he missed his train, and
so caught the one on which he
found this beautiful young woman sitting; suppose, further, that a super-computer could show that some of my
genes can be traced back to a small creature scrabbling about in the Triassic mud.
I'm heading to Portland, OR, for a friend's wedding,
so I'll be eating plenty, including at visits to Ava
Gene's and Maurice, where I'm hoping to
find something that channels a crunchy carrot slaw and this Maurice bostock, a sweet, bready revelation.
She is identifying the enzymes in these natural products to
find the
genes responsible
so that they can be introduced into other plants.
So Beller's team looked for just such a cluster of
genes among the candidate
genes in the toluenemaking sewage sample, and they
found the GRE phenylacetate decarboxylase (PhdB) and its activator, PhdA.
Now, a new study probing
so - called noncoding DNA has
found that alterations in regions that regulate
gene activity may also contribute to autism.
Tell me about the two - year Sorcerer II cruise, where you sampled a huge amount of ocean DNA —
so large that you concluded you
found 95 percent of all
genes known to science.
So Sandra Ryeom at the Children's Hospital in Boston and colleagues bred mice with three
genes to
find out if an extra copy gave them extra protection against cancer.
Despite the proliferation of GWAS, the associations
found so far have largely failed to account for the known effects of
genes on complex disease — the problem of «missing heritability.»
Yet, in this plant (as well as in certain conifers), the researchers
found genes similar to those responsible for the formation of flowers, and which are organized according to the same hierarchy (with the activation of one
gene activating the next
gene, and
so on)!
However, the team also
found virulence
genes in regions of the genome that are not
so variable.
Whether you are studying the expression of thousands of
genes simultaneously using DNA microarrays, or the interaction of multiple molecules to understand intercellular signalling, the skills that will help you understand your
findings are statistics, computational techniques, and modelling —
so all you really need is a mathematician.
That means that the approach that worked
so well for
finding the sweet receptor — identifying a likely
gene for the receptor, destroying it in mouse embryos, and proving that the resulting mice are unable to taste sweetness — will not work in the search for the salt receptor.
The American cockroach has
genes that code for more than 150 scent receptors and 500 taste receptors, the most
found in any insect
so far.
So we sequenced a
gene involved in cell growth and
found a correlation in about 85 percent of the patients: If you had a certain mutation in the EGFR
gene, you responded to the drug; if you didn't have the mutation, you didn't.
Then they put all six
genes into a single piece of DNA,
so that they would all be transcribed together — and
found that they could reconstitute the «3 - D printer» that assemble tubulin dimers.
Other molecules, called acetyl groups, were
found to play the opposite role, unwinding DNA around the histone spool, and
so making it easier for RNA to transcribe a given
gene.
Several mutations were
found in
genes coding the machinery that makes mitochondrial proteins, and
so would probably hinder mitochondria's ability to make the chemical fuel called ATP, which is used by normal cells.
We did not
find any evidence for a
so - called «positive selection» but instead
found that many
gene variants linked to schizophrenia reside in regions of the genome in which natural selection is not very effective in the first place.
Mitochondria carry only a few
genes, but they are
so plentiful that it's often easier to
find their DNA than the single full human genome in a cell's nucleus.
Most studies
so far have
found that educational achievement is influenced by a combination of thousands of
genes.
They say their study, published online in Endocrine Related Cancers, provides some surprising
findings about HDAC inhibitors, which all seemingly do the same thing — remove the HDAC enzymes that wrap DNA
so tightly that
genes are silenced.
Why
so many perish is unclear, though researchers have
found that many
genes are either over - or underexpressed in cloned embryos (ScienceNow, 12 September 2002).
Since the publication of the human genome sequence in 2001, scientists have
found that the
so - called junk DNA that lies between
genes actually carries out many important functions.
When researchers like Barzilai have looked for
genes that might account for the extreme longevity of the centenarians they study, they have typically
found that the
genes that stand out in one long - lived population do not do
so in others.
So,
finding a resistant male and getting his resistance
gene to her offspring is probably evolutionarily a good idea.
McRae and colleagues
found that the genetic variants associated all lie in or near
genes that encode
so - called odorant or olfactory receptors.
Research led by Margery Smelkinson
found that NS1 modulates the activitiy of a signaling cascade known as the Hedgehog pathway (
so named because fruit fly larvae lacking the Hedgehog
gene emerge hairless and resemble tiny hedgehogs).
The teams are yet to identify every
gene contained within this supergene region, but have
so far
found a
gene involved in colouring, which could explain differences in plumage, as well as
genes involved in processing sex hormones.
«It's important they've
found this
gene, but it took a sample of 20,000 people to
find it, precisely because the effect is
so small,» says Robert Plomin at the Institute of Psychiatry in London, and lead author of a groundbreaking study in 2007 which failed to
find any single
genes of disproportionate importance in intelligence.
«We're generating
so much sequence data right now, from
so many species, that it's relatively straightforward to look for signatures of selection in
genes and to
find good candidates for adaptations,» Montooth said.
Pinker says that the
findings are a first step in demonstrating that intelligence relies on large numbers of
genes, each with a tiny effect, rather than on single
genes that have moderate or large effects, but which are
so rare that none has yet been identified.
Although previous studies have
found that a large percentage of hair colour variation is explained by heritable factors, previous genetic studies only identified a dozen or
so hair colour
genes.
Although the
gene sequences were not identical to the Mikovits - Ruscetti XMRV
gene sequence reported in Science, they were
so close Lo believed he had
found genetic variants of a single MLV - like virus species that likely included XMRV.
So once researchers have identified the
genes of obesity, they must
find out how the
genes interact with a person's environment.
In a population with
so few individuals, an unhealthy mutant
gene will more often
find itself paired with the same mutant
gene in an offspring because the parents are related and of similar genetic makeup.
If correct, the
finding would add to growing evidence that this
so - called «speech
gene» is involved in communication in a wide variety of animal species.
«We have
found the
gene in the monkey, but
so far there has been no sign of fluorescence,» says Chan, indicating that the
gene has not yet been used to create proteins.
What we
found is that the ability of this chronic social stress to produce maladaptive changes in brain and behavior — loss of pleasure, inability to sleep normally and
so on — are mediated through epigenetic modifications of
gene expression, in particular, emotional centers of the brain.
Robertson's
findings fit nicely with Haig's theory: The paternal Igf2
gene encouraged growth of the offspring,
so it would make more demands upon its mother.
(Normally, multiple circular RNAs can be generated from a single
gene,
so it is not entirely surprising to
find different f - circRNAs emerging from the same fusion
gene.)
That
gene, called Wnt - 7a, is also suppressed by Engrailed - 1,
so it is active on only one side of the AER, and that side becomes the dorsal side, the researchers
found.
Zebrafish can
find a way to compensate for a mutated
gene, but artificial methods of inactivating the same
gene are not
so readily overcome, a new study suggests.
It's not that methylation doesn't do anything at all — in fact, the researchers
found that it is primarily associated with
genes that serve crucial functions for workers and queens alike, suggesting that DNA methylation might contribute to the stable expression of
so - called household
genes.
We know that
genes need to be conserved or nearly conserved,
so we'll
find lots of things we expect.
So when Page's team started sequencing the chromosome, they expected to
find a
gene - free runt or a genetic jungle whose sequence would consist mostly of repetitive, difficult - to - read gobbledygook.