Sentences with phrase «genes in»

The main aim was to identify the genes in the progenitor that allow it to resist the action of the insect's immune system.

The process, reported in Human Reproduction, utilizes DNA fingerprinting (an assessment of active genes in a given cell) to boost the success rate of IVF and lower the chances of risky multiple births by identifying which of several five - day - old embryos are most likely to result in pregnancy The new method, which will replace unproved alternatives such as choosing embryos based on their shape, is likely to up the success of women becoming pregnant and lower their chances of having multiple births.

Further tweaks to regulatory genes in the worm's metabolic pathways have upped its life span sixfold.

All cells contain the same DNA, but individual genes in any cell can be switched on or off by the addition or subtraction of a methyl group — a carbon atom bound to three hydrogen atoms.

The reason may well be due to methyl groups that were added in childhood to genes in her brain, thereby handcuffing her mood to feelings of fear and despair.

«Our finding from statistical analyses of all genes in the genome that SMCHD1 was the only plausible site of causal variants for arhinia — lack of a nose — was frankly shocking, since prior to our study no patients had ever been reported with both conditions.»

Duchenne muscular dystrophy is caused by a mutation to one of the longest genes in the body.

Then they compared the expression of thousands of genes in two samples by measuring levels of messenger RNA.

The team's results point to another strategy, however: using the same genes in different combinations, or «combinatorial coding.»

«Genes in the nucleus control the mitochondria, not the other way around,» he says.

And with CRISPR, they're able to break genes in up to 75 percent of Parhyale embryos, versus a maximum 25 percent success rate with the old technique.

«To be true genetic or germline therapy, you must modify genes in nuclear DNA.»

To learn which genes in the mussel make the byssal threads, the researchers first treated the threads with the enzyme pepsin to liquefy their interlocking networks of proteins.

«But there are 50 - plus MHC genes in mice, and we don't know what most of them do.

«Taken together, these results support the hypothesis that multiple myeloma cells express bone - related genes in a Runx2 - dependent fashion that mimics bone marrow resident cells and likely contributes to tumor survival and growth in the bone microenvironment,» Yang and colleagues wrote in the paper.

«What my student Rey did in a very innovative strategy was find genes in the chromosome of that organism that we thought were negatively affecting our ability to produce protein,» Jewett said.

But Aniket Gore of the US's National Institute of Child Health and Human Development and colleagues haven't found any disabling changes in the DNA sequences of eye development genes in the cavefish.

Already, researchers have used CRISPR / Cas9 to edit genes in human cells grown in lab dishes, monkeys (SN: 3/8/14, p. 7), dogs (SN: 11/28/15, p. 16), mice and pigs (SN: 11/14/15, p. 6), yeast, fruit flies, the worm Caenorhabditis elegans, zebrafish, tobacco and rice.

Besides differences in genes linked to brain development, Erik Axelsson of Uppsala University in Sweden and colleagues found three genes in dogs that are vital for digestion and extend their ancestral carnivorous diet to include starch (Nature, DOI: 10.1038 / nature11837).

Astoundingly, Venter says that his team could not identify the function of 149 of the genes in syn3.0's genome, many of which are found in other life forms, including humans.

Doyle is now tackling a far bigger network of genes in E. coli: the master network responsible for governing its metabolism.

With CRISPR, these researchers knock out so - called Hox genes in Parhyale.

«We'd like to extend this further to examine for driver genes in other types of lung cancer, such as squamous cell lung cancer.»

Although piRNAs have been known about for many years, scientists have until now had very little understanding of exactly how the piRNAs that guide PIWI proteins to jumping genes in the nucleus are produced.

Inheriting a single X chromosome exposes men to a host of X-linked diseases, such as hemophilia or Duchenne muscular dystrophy, and researchers hope to use the new data to understand more fully the role of genes in other X-linked conditions.

Barritt stresses that the 13 genes in mitochondrial DNA do nothing except provide proteins to produce energy.

Now, by harnessing advances in genome editing to slice and dice genes in donor T cells, researchers have created a new type of cancer immunotherapy.

A study in the journal Nature reports the discovery of rapid - growth genes in rice varieties that can withstand flooding by quickly rising above the new water line.

They arise in a unique subset of genes in which, after conception, the DNA in the embryo that came from the mother is expressed differently than the DNA from the father.

Basic neuroscience research in psychiatry and neurology is also making exciting use of the latest tools for manipulating genes in vivo.

Transcription factors are responsible for either inhibiting or promoting the expression of genes, and master regulatory transcription factors are like transcription factors on steroids: their actions regulate thousands of genes in different kinds of cells.

DNMT3A is among the most frequently mutated genes in an aggressive type of leukemia, and it plays a significant role in how this disease develops.

Finally, the team identified a network of genes in these regions that exhibit changes in expression when the normal boost from serotonin is lacking, and these changes depended on how long the drug was given.

Some of the genes in sperm and egg cells have chemicals called methyl molecules that attach to them, a process called methylation; these molecules can either activate or silence a gene when the sperm and egg DNA unite in an embryo.

«The story could be further enriched if there were data about prestin genes in echolocating birds and other echolocators, such as shrews,» he says.

It is being used as a genome - wide tool, to search thousands of genes in a cell and screen for their function.

This study examined the genetic code of affected patients with schizophrenia and their healthy parents to identify newly occurring (sporadic) mutations that disrupted the four influential signaling genes in 31 percent of these patients.

The result is that individuals with the most common form of the disease have a total of three copies of all the genes in this region.

If the genes in the chick embryo are very close to those of an ancestral, nonavian dinosaur — and if the changes, over more than 150 million years, have been almost all in regulation of the genes — then we could reactivate the old pattern of regulation.

Lupski was comparing genes in people with and without the disease in the hope of finding a gene variant unique to the condition.

To build a family tree for the orchids, the scientists sequenced genes in the green structures, called chloroplasts, in which plants transform solar energy into sugar.

One team, led by scientists in the United Kingdom and Brazil, drove more than 1,200 miles across Brazil — «a Top Gear — style road trip,» one scientist quipped — with a portable device that could produce a complete catalog of the virus's genes in less than a day.

They add that other genes in the region of the genome around Gp - 9 are probably involved in regulating fire ant social organization as well.

A few of those chromosomes have stayed intact — with their genes in the same order — over the past 105 million years, at least in orangutans and humans.

NASA astronaut Peggy Whitson performed the Genes in Space - 3 investigation aboard the space station using the miniPCR and MinION, developed for previously flown investigations.

«Although the development in the abundance of resistant genes in soil mirrors what you see in the health service, research has not yet made a connection between the two.

This pressure, together with possible interbreeding with migrating groups of smaller - brained peoples, may have led to a gradual decrease in the frequency of the Boskop genes in the growing population of what is now South Africa.

We have tested this hypothesis by estimating genomic point mutation rates for protein - coding genes in a range of animal taxa.

«Genes in children linked to stress, bipolar disorder.»

Genes in Space - 1 marked the first time the PCR was used in space to amplify DNA with the miniPCR thermal cycler, followed shortly after by Biomolecule Sequencer, which used the MinION device to sequence DNA.