Sentences with phrase «genes into»

The cystic fibrosis fix was elegantly simple: Deliver normal genes into the lung, and they would function in place of the faulty ones.

«It's much more difficult to insert genes into heart muscle, so this approach might be more effective.»

Researchers at Duke University Medical Center transplanted a set of human genes into a zebrafish and then used it to...

In particular, they are now looking for expertise in molecular biology, especially in virus - based techniques for introducing new genes into specific cell types in the grid - cell circuit.

He accomplished that with the help of a virus different from the retroviruses used initially: an adenovirus that brings the genes into a cell's nuclear area but doesn't become part of the cell's DNA; it disappears after it expresses the reprogramming genes.

PPI does not introduce any foreign genes into its products; rather it regulates the plant's own genes to increase or decrease expression of the genes responsible for key traits.

Because disease organisms mutate quickly to overcome crop resistance controlled by single genes, researchers are rushing to identify new resistance genes and to incorporate multiple genes into high - yielding varieties, according to Ravi Singh, CIMMYT wheat scientist who participated in the reported study.

Take a living elephant genome and cut and paste important mammoth genes into it so you get all the mammoth traits you want.

Getting edited genes into living birds can not be done with cloning, as it is with mammals.

In an earlier discovery, Dr. Srivastava's team at Gladstone showed that inserting three - to - seven genes into a skin cell can transform it into a beating heart cell, without passing through the pluripotent state.

Scientists and doctors who inject genes into healthy people violate professional ethical codes.

«Conventional techniques of producing transgenic animals, such as microinjection of genes into eggs and the retroviral transduction of genes into embryos, often produce many animals that are mosaic, which means they do not contain the foreign gene in all their cells.

'' There is no doubt in my mind that introducing passenger pigeon genes into the band - tailed genome will not result in tame birds that would easily be ensnared by men.

«But if we can add additional genes into the screening, we can refine the prediction of the disease, we can increase the accuracy, we can probably even identify higher percentages of at - risk individuals.»

These cells, first described in humans in November 2007, are produced by inserting certain stem - cell - associated genes into regular adult cells (like skin cells).

Yet in 2006, Shinya Yamanaka at Kyoto University in Japan reported a «crazy» experiment (Hochedlinger's word) to show that mouse skin cells in a petri dish, aided by four genes and viruses that inserted the genes into the cells» DNA, could achieve something like the newt's developmental reversal, becoming just about any cell in the mouse's body.

Hochedlinger has focused on the use of viruses to insert genes into cells, and has devised a way to produce iPS cells that only temporarily introduces reprogramming genes into the cells.

One such recent breakthrough is the use of a CRISPR formed from mouth bacterium that is capable of breaking RNA, the part of cells that help transform genes into usable proteins.

Scientists have developed very precise tools for cutting standard plasmids and splicing new genes into them.

«This data allows classification of all human protein - coding genes into those coding for house - hold functions (present in all cells) and those that are tissue - specific genes with highly specialized expression in particular organs and tissues, such as kidney, liver, brain, heart, pancreas.

Additionally, we support and expand upon the hypothesis that X inactivation is primarily driven by gene loss on the Y. Using linear discriminant analysis, we show that X-inactivation status can successfully classify 90 % of X-linked genes into those with functional or nonfunctional Y homologs.

Here's what Church had to say two years ago, when his lab reportedly had spliced mammoth genes into elephant skin cells:

Verma was the first scientist to genetically engineer HIV - based tools to insert new genes into cells.

The vector is a self - inactivating lentivirus — a member of a family of viruses that can insert genes into mammalian cells and drive expression of those genes — that has been engineered to avoid triggering the development of leukemia, a complication seen in previous gene therapy trials for immunodeficiency syndromes, including WAS.

Mixed ‐ ancestry and admixture in Kauai's feral chickens: invasion of domestic genes into ancient Red Junglefowl reservoirs.

In other words, transferring 45 of the largest - effect mammoth genes into an elephant all at once is unlikely to have a beneficial or useful outcome.

Another difficulty is that the gene that codes for dystrophin is too large to fit into the retroviruses that scientists use to insert genes into cells.

The ultimate outcome of their work might be not only the breeding of quinoa varieties with an even higher salt tolerance but also the crossbreeding of salt tolerance genes into related crop plants such as sugar beets or spinach.

Engineering mammoth genes into an elephant, with its much closer genetic background, sounds tempting.

Scientists speculate that mild, chronic stress — like a low - calorie diet or a cold room — may spark these genes into action.

B could work as a potential vector for gene therapy, a technique that treats diseases by introducing new genes into cells or by replacing or inactivating genes already there.

Cells make proteins by copying genes into RNA molecules, which serve as templates for building proteins.

Researchers can insert new genes into these or knock out existing genes with great precision.

Instead of using some fancy virus, why not just blast genes into cells with a gun?

In the current Proceedings of the National Academy of Sciences, biologists show that the herpes virus can shuttle human antipain genes into nerve cells in mice, increasing their tolerance for pain.

Viruses have genes composed of either DNA or RNA, and some integrate their genes into the host cell's DNA.

Their discovery of NIRVs in mammalian genomes corroborates a study in the 7 January issue of Nature in which John Coffin of Tufts University School of Medicine in Boston and colleagues reported that another group of RNA viruses that lack reverse transcriptase, bornavirus, can integrate their genes into mammals.

Keasling says that his team will try to improve both of those issues by engineering similar genes into yeast, a more industrially useful microbe.

To date, however, this research has been slowed by the inefficiency of the viruses that are now used as vectors to carry new genes into cells.

In the early 1980s, genetic engineering had just made the leap from the laboratory to the boardroom, as corporations made small fortunes inserting genes into Escherichia coli to produce insulin, growth hormones, and other valuable molecules.

He studied plasmids, tiny ringlets of DNA that genetic engineers use to insert foreign genes into bacteria.

Working with French composer Richard Krüll, the pair turned the complete nucleotide sequences of several microbe genes into compositions based on DNA bases: A (adenosine), C (cytosine), G (guanine), and Thymine (which they have translated to «Re,» or D).

Scientists have introduced genes into the American chestnut from wheat that help disarm the fungus that killed almost all three billion of the trees in the eastern U.S. David Biello reports

Notably, this ESC / E (Z)(Extra Sex Combs / Enhancer of Zeste) gene complex regulates epigenetic mechanisms that govern the transcription of genes into proteins in response to the environment — including sex hormones and stressors.

They inserted genes into neurons that would activate the cells when exposed to light.

To insert genes into a cell, scientists often prick it with a tiny glass pipette and inject a solution with the new DNA.

In the 1970s, genetic engineers began inserting genes into microbes and enlisting them to make drugs or insecticides.

But when retroviruses like HIV infect a cell, they often let the cell live and splice their genes into its DNA.

Using «homologous recombination,» CRISPR can also be used to insert new DNA sequences or even whole genes into the genome in a precise way.

Modern breeding has resuscitated grocery store tomatoes with an influx of wild genes; in the past 50 years, researchers have bred back some 40 disease - resistance genes into commercial crops.