Sentences with phrase «genes into body cells»

Not exact matches

The team believes that whichever way BMP - 7 is used, it will be less risky than other treatments for type 1 diabetes that are currently being investigated, such as those that create pancreatic cells from stem cells, or by introducing new genes into the body.

By turning on a several genes in adult cells, scientists can transform skin or blood cells into stem cells that can become every cell type in the body — without the ethical and practical complications of using embryos or oocytes.

The team's biggest finding was that dsRNA can travel from body cells into germ cells and silence genes within the germ cells.

Taking advantage of this, researchers can insert therapeutic genes into a virus, then use the viruses to shuttle the genes to the appropriate cells or tissues inside a human body.

A large body of research has reported that Nanog is allelically regulated — that is, only one copy of the gene is expressed at any given time — and fluctuations in its expression are responsible for the differences seen in individual embryonic stem (ES) cells» predilection to differentiate into more specialized cells.

In a series of studies this year, molecular geneticists at the University of Pittsburgh School of Medicine used a harmless virus to ferry new genes through the bloodstream, across blood vessel walls, and into almost every muscle cell in the bodies of hamsters bred to have human genetic diseases.

This will offer us unique insights into the relationships between epigenetics and gene activity and will help us to better understand the processes that convert a single cell into the many different cell types in the body.»

Not unlike looking for the proverbial needle in a haystack, a team of Michigan State University researchers have found a gene that could be key to the development of stem cells — cells that can potentially save millions of lives by morphing into practically any cell in the body.

When it's done inside the body, doctors may inject the virus carrying the gene in question directly into the part of the body that has defective cells.

They then stitched the genes for these immunoadhesins into an adeno - associated virus (AAV), a «vector» used in human gene therapy experiments to deliver foreign DNA into the body's cells.

IPS cells are grown in culture from body cells, through the addition of genes that cause them to revert to pluripotency — the stage in which they can potentially develop into any type of body cell.

By adding three genes, they converted those cells into induced pluripotent stem cells (iPSCs), which have the capability to differentiate into any cell types in the body.

One method is to remove some tumour cells from the patient at the time of surgery, insert a gene for an immune - stimulating protein into them, and return them to the body.

Yet in 2006, Shinya Yamanaka at Kyoto University in Japan reported a «crazy» experiment (Hochedlinger's word) to show that mouse skin cells in a petri dish, aided by four genes and viruses that inserted the genes into the cells» DNA, could achieve something like the newt's developmental reversal, becoming just about any cell in the mouse's body.

Then, using more lab tricks, scientists can re-introduce their home - grown version of the Huntington's disease gene into mouse cells and grow new mice that have it in every cell of their body.

Unlike the case of most gene therapies that are intended to permanently alter their target cells, however, Oisín's senoablative genetic constructs will not be inserted permanently into the patient's genome: instead, its genetic payload will be expressed temporarily from the main body of the cell, following which the construct will be passively degraded by normal cellular metabolism.

From a cheater's perspective, it's better to inject a gene for making a hormone than to inject the hormone itself because the gene converts cells into hormone - making factories, while the hormone must be injected again after the body clears it.

Fundamental Science Overview Gene and gene - modified cell therapies treat diseases by delivering therapeutic DNA into a patient's cells, either in (in vivo) or outside his or her body (ex viGene and gene - modified cell therapies treat diseases by delivering therapeutic DNA into a patient's cells, either in (in vivo) or outside his or her body (ex vigene - modified cell therapies treat diseases by delivering therapeutic DNA into a patient's cells, either in (in vivo) or outside his or her body (ex vivo).

Surprisingly, by introducing only a few genes, he could reprogram mature cells to become pluripotent stem cells, ie immature cells that are able to develop into all types of cells in the body.

The technique involves replacing a mutated copy of the gene with a healthy copy in stem cells isolated from the patient, which are then transfused back into the body — a process known as autologous stem cell transplantation.

A patent application has been filed and testing is underway on the protein — called HT - TALENs (short for HIV - targeted transcription activator - like effector nucleases)-- which uses a newly developed gene - editing technique to rid the body's cells of the immunodeficiency virus before it has a chance to multiply and possibly develop into AIDS.