Sentences with phrase «genes known»

Although the study of psychological genetics is in its infancy and much is still to be learned, in this article, we present data suggesting that variation in several genes known to affect brain function appear to influence the degree to which one is emotionally responsive to the social environment.

It lists the various genes known to impact Aussie coat color, the different versions of the genes, and which combinations result in which colors or patterns.

In collaboration with veterinary neurologists in England, researchers at the Hospital for Sick Children compared the genes known to be associated with Lafora to the same genes in affected dogs.

Our test is the only dog DNA test that provides true genetic size not based just on breed ancestry but based on over a dozen genes known to influence a dog's weight.

Typically, a major transcription factor involved in the expression of detoxification genes known as Nrf2 remains in a dormant state in the body.

genTrue genetic testing includes 26 genes known to increase risk for multiple common cancers, including breast, colorectal, prostate, and others.

At the conclusion of the study, the mice given whole soybean foods had lower levels of cancer - causing genes and higher levels of cancer - suppressing genes, as opposed to the isoflavone group which had high levels of cancer - causing genes known to «hide» cancer cells from the body's immune system.

As both bacterial and viral genomes were detected in the present brain specimens, we examined host genes known to participate in responses to infections.

The paucity of single nucleotide diversity among breeds is consistent with other studies (29 — 32) and stands in stark contrast to the abundance of coding repeat variation we found in these same genes known to be involved in the developmental processes under selection in the radiation in dog breed morphologies.

Inherited loss of hearing can be caused by mutations in any of over a hundred of genes known to affect hearing, a...

The dorsal pancreatic bud was enriched for components of Notch, Wnt, BMP, and FGF signaling, almost all genes known to cause pancreatic agenesis or hypoplasia, and over 30 unexplored transcription factors.

The plates contained genes associated with proliferation and apoptosis, to confirm our in vitro findings that no changes occurred, as well as genes known to identify / enrich for CSC and those involved in CSC signaling.

The MyAML and MyHEME cancer panels are designed to analyze and interpret sequence information in genes known or suspected to be involved in AML and other hematologic diseases, respectively.

(C) qPCR analysis of mRNA levels for VEGF, GLUT1 and MCT4, the genes known to be targets for HIF1α.

Genes known as BRCA1 and BRCA2 are involved in cell growth and the repair of damage to DNA.

SLC16A11 belongs to a family of genes known to transport molecules across cell membranes, but the proteins that genes produce can perform many different roles in the body, and they can be active in some tissue types but not others.

Her team first looked at 15 obese and 20 lean Labrador retrievers two years ago, examining three genes known to affect obesity and weight in humans.

In 114 genes known to be associated with cancer, they found rare germline mutations in all 12 cancer types, but in varying frequencies depending on the type.

In all the cancer cases they analyzed, the investigators looked for rare germline mutations in genes known to be associated with cancer.

In this review, I highlight the main genes known to cause uncommon monogenic forms of diabetes (e.g. maturity - onset diabetes of the young — MODY — and insulin resistance syndromes), as well as describe some of the main approaches used to identify genes involved in the more common forms of T2D that result from the interaction between environmental risk factors and predisposing genotypes.

They did their best to filter out genes known to have random monoallelic expression, single - allele expression due to sequence variants, or RNA patterns that might look like monoallelic expression due to technical issues with the sequencing.

De Man and his collaborators identified four genes known to confer resistance to beta - lactams, a family of broad spectrum antibiotics often used to treat gram - positive and gram - negative infections.

The researchers used a technique called RNA interference (RNAi) to screen a group of genes known to be involved in animal development, in order to study the signaling mechanisms that regulate whether the animal would produce a head or tail during regeneration.

Egr3, which belongs to a family of immediate early genes known as early growth response (Egr) genes, is another target gene for BDNF.

Specifically, the regular oscillations of other circadian genes in the brain and the liver became disrupted, as well as genes known to regulate glucose and lipid metabolism.

The programme conducts more than 2,000 genetic studies annually to determine mutations in the BRCA1 / 2 genes and in other genes known to be related to breast cancer.

«85 % of these genes are required for nephrocyte function, suggesting that a majority of human genes known to be associated with NS play conserved roles in renal function from flies to humans,» said Zhe Han, Ph.D., senior author of the paper and Associate Professor at the Centre for Cancer and Immunology Research at Children's National.

The Nature Genetics studies add another four — MS4A, CD2AP, CD33, and EPHA1 - and contribute to identifying and confirming two other genes, BIN1 and ABCA7, thereby doubling the number of genes known to contribute Alzheimer's disease.

Most genes known to be associated with type 1 diabetes — including those currently considered the top two high - risk genes, which are the ones TEDDY screens for — are classified as human leukocyte antigen, or HLA genes.

This allows their brain to develop normally, but also triggers the development of cancer by adding mutated ATRX genes and other genes known to be involved in cancer.

Genes known to directly interact specifically with the NR1 subunit of the NMDA receptor were identified using HiMAP databases.

The cells expressed many genes known to be expressed in primordial germ cells, and underwent a genetic reprogramming process called demethylation associated with sperm production.

Other medical sequencing projects will use DNA sequencing to: discover new genes that are involved in common diseases; identify the genes responsible for dozens of relatively rare, single - gene (autosomal Mendelian) diseases; sequence all of the genes on the X chromosome from affected individuals to identify those involved in sex - linked diseases; and survey the range of variants in genes known to contribute to certain common diseases.

A May study in Nature found that 65 percent of autistic children share a set of mutations that may regulate genes known to influence communication among brain cells.

They found that the associated regions contained numerous candidate genes, among them genes known to affect ear function, language development, memory, bird song and the brain's reward mechanism.

As Ganguly - Fitzgerald says: «Of all genes known to cause human disease, more than 60 percent are found in the fruit fly.»

Their classification is based on differences in the DNA sequences of two genes known as gag and env.

Known as Slit and Trk - like family member 1 (SLITRK1), it was related to a group of genes known to be involved in neuronal growth, guidance, and branching.

They then homed in on glitches in 40 genes known to be involved in neurological disorders.

That's about 2000 years earlier than suggested by previous studies focusing on a different, more selective set of genes known as the exome, but it's in line with recent archaeological findings that point to distinctly Tibetan permanent settlements appearing between 3600 and 5200 years ago, Yang says.

Their findings expand the number of genes known to cause CMT1, further helping neurologists and patients find the genetic underpinnings of their neuropathy.

All of these children did not have mutations in other genes known to cause glaucoma.

A new study has found strong evidence that tobacco use can chemically modify and affect the activity of genes known to increase the risk of developing cancer.

Furthermore, eliminating a number of the genes known to work in the same gene pathway as Notch created similar chaotic patterns in the embryos, they report in the 18 June issue of Nature.

Certain malignant brain tumors and leukemias have mutations in genes known as IDH1 and IDH2.

In the cells of babies with microcephaly, three genes known to be involved in neural development were less active.

One they came upon was Ufd1 (for ubiquitin fusion degradation), which was one of 25 or so genes known to lie within the DiGeorge deletion site.

Their goal: to track the evolution of a family of genes known as relaxins.

The overlap, they found, wasn't just in those genes known to determine the sex of an embryo.

Gene panel testing denotes the simultaneous analysis of dozens of genes known to influence CRC risk.