Sentences with phrase «genes on chromosome»

[A] DNA variation found between the PGCP and MTDH / AEG -1 genes on chromosome 8 appears to be associated with increased susceptibility to common migraine.

Studies in mice and other animals have uncovered clues about the function of a few of the genes on chromosome 21, but many remain understudied.

«This work showed that conflicts are a universal problem for all genes on the chromosome,» says Merrikh.

Genome mapping is used to identify and record the location of genes and the distances between genes on a chromosome.

The arrangement of genes on the chromosome is not a map of the plant's regulatory circuits.

The reason has been a mystery, but some researchers suspect it has to do with one or more of the genes on chromosome 21, which people with Down syndrome have three copies of instead of the normal two.

Scientists this month unveiled evidence that an estimated 1 percent of all autism cases may stem from a structural change involving 25 to 30 genes on chromosome 16.

In 2004 Guilherme Neves and Andrew Chess, now at the Center for Human Genetic Research at Massachusetts General Hospital, tracked the roles played by other genes on chromosome 21 — in this case using a fruit fly as the model.

However, these studies didn't home in on any specific genes on this chromosome.

One case where the ordering of genes on a chromosome is important to their function is that of the Hox genes, which define the body patterns of most types of animals during development.

Scientists investigated Williams syndrome or WS, a rare genetic condition caused by deletion of one copy of 25 contiguous genes on chromosome 7, out of an estimated 30,000 genes in the brain.

A further mystery is whether the order of genes on a chromosome and the spacing between them influence their functions.

They found that the number of copies of lncRNA genes on a chromosome consistently change in 12 different cancer types and lncRNA genes are widely expressed in cancer cells.

In Angelman's syndrome a child receives two copies of genes on chromosome 15 from his or her father, and a single inactivated copy of those genes from his or her mother.

They found 3491 matching chunks, but only 1229 corresponded to known genes on chromosome 21.

But in a closer study of 73 families researchers found a region of genes on chromosome eight in those with perfect pitch and from European ancestry.

To learn more, Zanders and her colleagues used genetic mapping to reveal the complex landscape of multiple meiotic drive genes on chromosome 3 of S. kambucha.

After demonstrating the existence of several genes that control indefinite cell division, she, a grad student named Yi Ning, and their colleagues found a candidate for one of those genes on chromosome 4.

Alzheimer's disease is likely due to a defective gene on chromosome 21.

Our genome is nearly identical to the chimpanzee genome, a little less identical to the gorilla genome, a little less identical to the orangutan genome, and so on — and this correspondence is present in ways that are not needed for function (such as the location of shared genetic defects, the order of genes on chromosomes, and on and on).

AN EXTRA copy of a gene on chromosome 21 may explain why people with Down's syndrome are less likely to get breast and lung cancer than the rest of the population.

When the researchers compared the mRNA to a library of DNA sequences taken from the dendrites of neurons by James Eberwine of the University of Pennsylvania Medical Center, they found that it came from a single gene on chromosome X — the human version of which, when mutated, leads to fragile - X syndrome.

A gene on chromosome 21 called DSCR1 is involved in controlling tumour growth.

She lacks the gene mutations present in the other children but has mutations in a gene on chromosome 17 called CBX2.

That's in contrast to the impact of a gene on chromosome 20 that increased protein concentration but also significantly decreased yields in soybean varieties.

In one experiment with human cells, a guide RNA should have led the Cas9 enzyme only to a gene on chromosome 2 (yellow bar), but it also directed the enzyme to many off - target sites (red) on several other chromosomes.

Rudolph Tanzi of Massachusetts General Hospital in Boston and Ellen Wijsman of the University of Washington, Seattle, both say that they have checked large databases and have found «no evidence» of an AD gene on chromosome 12.

«We found that this gene on chromosome 15 consistently increased protein concentration,» ayssays Diers.

About 4 percent of people in the study carried one of these two rare variants, which are located in the vicinity of the MGST1 gene on chromosome 12.

A locus is the position of a gene on a chromosome.

We report here 13 mutations in the fused in sarcoma / translated in liposarcoma (FUS / TLS) gene on chromosome 16 that were specific for familial ALS.

Newly developed approaches that use CRISPR / Cas9 gene editing technology can generate offspring that carry copies of the altered gene on both chromosomes — a phenomenon called super-Mendelian inheritance that, in theory, should quickly convert an entire population.

They have found a gene on chromosome 21 which they believe is responsible for many cases of the disease.

Now they have singled out a gene on the chromosome.

She published her discovery of the epilepsy in 1994, the same year that researchers in Finland identified its gene on chromosome 8.

CEPH's «first - generation» map, assembled by hundreds of researchers and with financial support from the US National Institutes of Health in Bethesda, is based mainly on the relative positions of genes on chromosomes.

By identifying linked genes, researchers can build up a picture of the relative positions of genes on chromosomes.

However, a similar gene on another chromosome plays a role in some forms of male infertility.

Likewise, one version of the APOE gene on chromosome 19 predicts the likelihood of a boxer suffering from premature Alzheimer's disease.

A well - studied example of a human gene is the ACE gene on chromosome 17, which seems to predict physical performance.

The earlier «discovery» of a suspect gene on chromosome 11 turned out to be wrong.

Huntington's disease is an hereditary disorder of the nervous system caused by a faulty gene on chromosome four.

The Science paper, by developmental biologist Ethan Bier and his student Valentino Gantz at the University of California, San Diego, used CRISPR to insert a modification into genes on both chromosomes in a pair, so that when the flies bred, they would pass the modification on to practically all of their offspring.

But scientists from the Julius - Maximilians - University of Wuerzburg in Germany have zeroed in on one mutation of a gene on chromosome 22 that appears to play an important role in catatonic schizophreniaa particularly severe form of the disease characterized by acute psychotic breaks and disturbed body movements.

The mutation causing this form of early - onset Alzheimer's is called E280A and is found in a gene on chromosome 14.

The evidence suggests it does: 249 pairs of siblings were more likely to both have diabetes, or both be healthy, if they shared the same set of genetic markers in the region of the IL - 12 gene on chromosome 5.

In the October issue of Nature Genetics, Siddique's team writes that a mutated gene on chromosome 2 common to both families encodes a novel protein they dubbed alsin.

«The controversy over whether these disorders are completely distinct has been going on for decades, but the recent evidence strongly favors at least some shared genetic elements,» says psychiatrist Eliot Gershon of the University of Chicago, whose team recently identified a gene on chromosome 13 that is associated with both illnesses.

Now Cecilia Lai, Simon Fisher and colleagues, reporting in todays Nature, show that a gene on chromosome 7, which they call FOXP2, is mutated in the affected members of the KE family, as well as in an unrelated patient with a similar language deficit.

The result is that a fusion gene is created by juxtaposing the ABL1 gene on chromosome 9 (region q34) to a part of the BCR (breakpoint cluster region) gene on chromosome 22 (region q11).