Sentences with phrase «genes result in»

In Labradors, the B and E genes result in black, yellow, and chocolate Labradors.

Disease - linked mutations in these genes result in increased production of the 42 - amino - acid form of the peptide (Abeta42), which is the predominant form found in the amyloid plaques of Alzheimer's disease.

Indeed, mutations in multiple lysosomal genes result in severe neurodegeneration and it is becoming more clear that lysosomes also play a neuroprotective role in more common neurodegenerative diseases such as Alzheimer's disease that have not traditionally been associated with lysosomal defects.

Mutations in the majority of these genes result in isolated hearing loss (meaning not part of a more complex hearing loss syndrome such as Usher Syndrome).

How the same genes result in two types of individuals is an ongoing mystery.

Maggie: Named for the youngest Simpsons character, these mutated genes result in arrested physical development.

Ovarian cancer cells use autophagy all of the time, but also lose several copies of autophagy genes resulting in a compromised capacity.

George Daley of Harvard Medical School said on December 1 that he and his team have seen multiple patients affected by NEMO deficiency syndrome, a disorder where an inherited faulty gene results in a weak immune system and leaves patients prone to serious infections.

In this mouse model, mutations in Kras and p53 genes resulted in the formation of individual tumor cell populations that were labeled with different colors.

The deletion of one copy of the gene resulted in substantial improvements in most symptoms, while deleting both copies eliminated them almost completely.

They found that two specific genes, DLX1 and DLX2, regulate GABA synthesis during brain development, and that mutations to the genes resulted in abnormal brain maturation.

The divergent evolution of a duplicated gene results in genetic incompatibilities between strains of the plant Arabidopsis.

The GJB6 gene encodes the CONNEXIN 30 protein, which is essential in hearing development, and a deficiency of the gene results in the second most common disease among cases of hereditary hearing loss that have no other disease in the inner ear.

Mutations in this gene result in a pituitary disorder resulting in short stature, but those mutations have not been seen before in Pygmies.

In a study published in the journal Cell on July 14, the researchers found that placing enhancers in different positions relative to their target genes resulted in dramatic changes in the frequency of the bursts.

Too many CAGs in a gene results in proteins with too many «glutamine» building blocks, and glutamine is represented by the symbol Q.

Also, a different targeting approach leading to the use of the native 3 ′ UTR and removal of the neo gene resulted in normalisation of XpdXPCS mRNA levels and viable homozygous XpdXPCS / XPCS (XPDG602D / G602D) animals [23].

Partial knockdown of this gene resulted in atypical behavior in 7 dpf larvae, as was measured in DanioVision using a light - dark - light paradigm (15-45-45 minutes).

The expanded CAG sequence in the HD gene results in a huntingtin protein with too many glutamines at the start of it.

Knockdown of both dec1 and per2 genes resulted in a noticeably disrupted circadian locomotor activity pattern.

Studies have shown that pathogenic loss - of - function variants in this gene result in various types of epilepsies, mostly beginning early in life.

Conclusions: These patients demonstrate that heterozygous, likely dominant negative mutations affecting the protein kinase domain of the CDK13 gene result in a recognisable, syndromic form of intellectual disability, with or without congenital heart disease.

A separate study discovered that some of these Neanderthal genes resulted in adaptations that were both beneficial and detrimental for modern humans.

Typically the Corgi has a tan and white coat however Corgis can carry the Merle gene resulting in a Merle Coat.

A genetic variant within this gene results in a «diluting» or lightening of the coat color of dogs.

Not exact matches

In February, the FDA agreed to allow 23andMe and its competitors to resume marketing tests for autosomal - recessive diseases, which result when both parents carry an abnormal gene.

To date, no gene therapies have yet been approved in the US, though one to treat another form of LCA has had promising results in late - stage trials.

Instead of just focusing on human DNA, which in the other studies had yielded limited results, she looked at multiple sets of genes — and not just from humans.

«The services segment will grow between 13 per cent and 20 per cent per year over the next five years driven by continued growth in existing services along with new, innovative services,» Gene Munster, co-founder of Loup Ventures and a veteran Apple analyst, wrote in an email following the results on Tuesday.

(RTTNews)- Today's Daily Dose brings you news about FDA panel's vote on Achaogen's Plazomicin; Karyopharm's public offering; Cellectis» progress in TALEN gene - edited product pipeline; Globus Medical's Q1 financial results; a federal Court's ruling, which has gone in favor of Progenics / Valeant, and...

anemia and others result from a misplaced base letter in a single gene.

One of the key caveats at the time, however, was that the technique required the use of a virus to introduce several genes into the skin (or other) cell, and these would remain in the cell, and so might contaminate the resulting stem cell or create cancer risks.

Think about it, these single gene changes are usually what results in tumor formation, right?

When that devotion results in death however... To put it bluntly, this man is now quite unlikely to pass his genes / ideology on to the next generation.

The happenings we know a lot about, thanks to evolutionary biology, particularly of the last four decades, are the roles of mutation, recombination of genes in sexual reproduction resulting in a great diversity of gene arrangements, and natural selection.

Evolution occurs at the microscopic level by changes in genes as a result of the survival of the most adapted organisms for the environment in which they live.

The PSTOL1 gene is also being tested in rice varieties for the more productive irrigated rice - growing areas and initial results show that the plants grow a better root system and have higher production too.

In a bizarre irony, the players» union — Don Fehr and Gene Orza and the lot — which had fought ferociously against drug testing, failed to ensure that the results from a 2003 survey test remained anonymous.

Getting a durable LIGHTWEIGHT stroller is more important than anything else if you think your genes will result in tall and / or sumo wrestler weight children.

There's also a 25 percent chance the child will have two genes for achondroplasia, which often results in death shortly after birth, but there's also a 50 percent chance the child will be born with dwarfism.

The scientists were interested in understanding what factors influenced women to share test results, particularly with their children, who might also be affected by the cancer - conferring genes.

The disruption of prenatal cellular activity in zebra fish, which share 80 percent of their genes with humans and are considered a good model for studying human brain development, seemed to result in hyperactivity, according to the Canadian study, which was published Monday in the Proceedings of the National Academy of Sciences.

Therefore, variation in RNA quality across lactation stage must be considered when interpreting gene expression results across postpartum time points.

It has been estimated that 5 % to 10 % of infants who die from SIDS have novel mutations in the cardiac sodium or potassium channel genes that result in long QT syndrome as well as in other genes that regulate channel function.44 A recent report described important new molecular and functional evidence that implicates specific SCN5A (sodium channel gene) β subunits in SIDS pathogenesis.47 The identification of polymorphisms in genes pertinent to the embryologic origin of the autonomic nervous system in SIDS cases also lends support to the hypothesis that a genetic predisposition contributes to the etiology of SIDS.

«The dairy industry in New York and across the U.S. has received decades of unwarranted government support, and the health of our nation has suffered as a result,» wrote Gene Baur, president of Farm Sanctuary in Watkins Glen, to Gov. Andrew Cuomo.

The unofficial election results are in from the county boards of election: In Delaware County: In the town of Sidney, Republican Gene Pigford wins the Supervisor position; winning town council seats were Democratic incumbent Pete Cordes, & Republican John Woodyshek... Continue readingin from the county boards of election: In Delaware County: In the town of Sidney, Republican Gene Pigford wins the Supervisor position; winning town council seats were Democratic incumbent Pete Cordes, & Republican John Woodyshek... Continue readingIn Delaware County: In the town of Sidney, Republican Gene Pigford wins the Supervisor position; winning town council seats were Democratic incumbent Pete Cordes, & Republican John Woodyshek... Continue readingIn the town of Sidney, Republican Gene Pigford wins the Supervisor position; winning town council seats were Democratic incumbent Pete Cordes, & Republican John Woodyshek... Continue reading →

Various chemical modifications of these histone proteins will result in an increase or decrease in the relevant gene activity.

The result was an 18,000-fold improvement in noscapine output, compared with what could be obtained by just inserting the plant and rat genes into yeast.

«Currently, we are conducting a series of joint investigations on gene family evolution and adaptation genomics in plants with colleagues at the Chinese Academy of Sciences, and we foresee more significant results from this collaboration,» says Xiao - Ru Wang.

After determining the proper dosage of tamoxifen — an early trial resulted in a number of mouse deaths due to overactivation of Mecp2 — researchers settled on a four - week regimen of ramping up the gene's function.