The discovery of one of
the genes resulted from the analysis of high - density SNP and microsatellite genotyping of more than 900 men with high body - mass index (BMI) and several hundred non-obese relatives and random controls.
The new knowledge and target candidate
genes resulted from such unbiased study are ultimately important for researchers to understand the fundamental nature of stem cell proliferation and differentiation.»
Not exact matches
Now instead they transfer
genes from the soybean plant into the yeast, grow the yeast, and then isolate the heme protein
from the
resulting broth.
Instead of just focusing on human DNA, which in the other studies had yielded limited
results, she looked at multiple sets of
genes — and not just
from humans.
There are a wide range of reproductive strategies
resulting from the competing interests at various levels of selection, that is, the level of individual
genes /
gene clusters, the level of the individual and the level of the population / species.
anemia and others
result from a misplaced base letter in a single
gene.
The death of much - loved actor
Gene Wilder due to complications
resulting from Alzheimer's has put the... More
In a bizarre irony, the players» union — Don Fehr and
Gene Orza and the lot — which had fought ferociously against drug testing, failed to ensure that the
results from a 2003 survey test remained anonymous.
It has been estimated that 5 % to 10 % of infants who die
from SIDS have novel mutations in the cardiac sodium or potassium channel
genes that
result in long QT syndrome as well as in other
genes that regulate channel function.44 A recent report described important new molecular and functional evidence that implicates specific SCN5A (sodium channel
gene) β subunits in SIDS pathogenesis.47 The identification of polymorphisms in
genes pertinent to the embryologic origin of the autonomic nervous system in SIDS cases also lends support to the hypothesis that a genetic predisposition contributes to the etiology of SIDS.
The unofficial election
results are in
from the county boards of election: In Delaware County: In the town of Sidney, Republican
Gene Pigford wins the Supervisor position; winning town council seats were Democratic incumbent Pete Cordes, & Republican John Woodyshek... Continue reading →
Resulting from the meeting was the St. Petersburg Declaration on
Gene Doping, which includes policy recommendations.
«Currently, we are conducting a series of joint investigations on
gene family evolution and adaptation genomics in plants with colleagues at the Chinese Academy of Sciences, and we foresee more significant
results from this collaboration,» says Xiao - Ru Wang.
Next, the authors compared their stickleback
results to previously published opsin
genes in two related species of fish (bluefin killifish and black bream), separated
from sticklebacks by millions of years, that had also adapted to blackwater and clearwater habitats.
That
result, reported in a paper posted online December 1 at BioRxiv.org, directly contradicts a previous study concluding that tardigrades got about 17 percent of their
genes from bacteria and other organisms.
The
genes responsible for these proteins undergo frequent point mutations,
resulting in genetic «drift»; moreover, the
genes from different animal and human strains may also interchange,
resulting in genetic «shift.»
This suggested that obesity in both obese and db mouse strains
resulted from a mutation in a single
gene in each case.
Known in Catalan as Floquet de Neu, Snowflake became a famous resident of the Barcelona Zoo in Spain because of his unique skin color, the
result of a rare albinism
gene inherited
from both parents.
The disease
results from a single mutation in the
gene that codes for one of the protein chains that make up the hemoglobin molecule.
Astronaut
Gene Cernan saw an extended glow in the sky which may have
resulted from light scattering off the stuff.
The grueling 18 months unearthed a gold mine: Lundblad's team found three
genes that are crucial for telomerase function,
results that generated a flurry of groundbreaking papers
from the members of her group in 1996 and 1997.
AveXis, Inc., a clinical - stage
gene therapy company developing treatments for patients suffering
from rare and life - threatening neurological genetic diseases, announced in July 2016 that the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation for the treatment based on preliminary clinical
results from the trial of AVXS - 101.
This finding suggests that the homologous region may have
resulted from a duplication of an ancestral
gene and that the two
genes evolved further by recruitment of exons
from other
genes, which provided the specific functional domains of the LDL receptor and the EGF precursor.
However, the
results of more recent phylogenetic analyses, derived
from comparisons between sequences of specific
genes and of whole genomes, seemed to point to Ctenophora as the first group that parted company with the lineage
from which the rest of the animal kingdom (including sponges) evolved.
«Our lab took part in analysing the group of RNA or transcriptome, that
results from transcription, the process by which the instructions in the
genes are read.
«The significance of mutations in this
gene is astonishingly clear
from these
results: it simply doesn't exist where there is no leukemia,» says Dr Naomi Park, joint first author
from the Sanger Institute.
Now scientists are attempting another task: avoiding unintended mutations
resulting from their
gene edits.
A mutant in the corresponding
gene from arabidopsis is already known, but here it was only known that — as the mutant name Snowy Cotyledon indicates — it
results in white cotyledons (the first two leaves).
Patients with Parkinson's disease may be the first group to benefit
from gene therapy, the much hyped technique that has yet to
result in a single reliable treatment despite nearly two decades of experimentation.
These
results indicate that the large losses of cloned cows before implantation probably
result from problems with critical developmental
genes in the extraembryonic tissue.
Novel abnormalities in the FGFR
gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary
results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit
from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.
In Martin's view, the
result strongly suggested that the patients had inherited the silenced
gene from one of their parents, like the case with agouti mice.
The aim is to ensure that the benefits
resulting from researching animals, plants and microorganisms, such as the invention of new medicines or enhanced
genes to improve crop varieties, are «fairly and equitably shared» among the providers and users.
The researchers did see a decrease in seed oil concentration
resulting from the
gene.
The first is that since all diseases
result from gene - environment interactions, and we can not reengineer our
genes, the most effective way to prevent mismatch diseases is to reengineer our environments.
One
gene, called ZNF659, showed over-methylation in people with schizophrenia and under - methylation in those who were bipolar, suggesting that the conditions might
result from opposing
gene activity (Human Molecular Genetics, DOI: 10.1093 / hmg / ddr416).
The next step, he said, is to demonstrate the same
results among those called protananamolous, who suffer
from a less common form of color blindness involving an overabundance of red pigment
genes.
The breakthrough has
resulted from the merger of interlocking fields —
gene therapy and cell therapy — which are now spawning near - miraculous treatments and cures.
Nor does not having the
gene mean the person will remain disease free, because many diseases
result from interactions of multiple
genes and the environment.
Angelman syndrome, which causes learning difficulties, speech problems, seizures, jerky movements and an unusually happy disposition,
results when a
gene inherited
from the mother in a particular area of chromosome 15 is mutated and the other copy of the
gene, inherited
from the father, is silenced.
Perhaps, he said, the technique could be modified to work in other diseases that
result from mutations in imprinted
genes.
She and her colleagues will be exploring the role of YY1 further, using clinical samples as well as mouse models, to look at the protein in diseases like lupus to deepen their understanding of how autoimmunity could
result from the «escape» of immune
genes from X chromosome inactivation.
Diversity
results from the re-assortment of
genes during meiosis and genetic mutation.
In 2011, Science's editors will be watching a smaller detector at the Large Hadron Collider called LHCb, which will study B mesons in great detail; new techniques that should lead to the discovery of many more
genes contributing to adaptation; an ignited fusion burn at the National Ignition Facility; broadly neutralizing antibodies, which are capable of disabling a wide range of viral variants; the first plug - in hybrid electric cars whose batteries are charged
from a wall socket go on the market; and the
results of the first phase III trial of a malaria vaccine.
The research team
from the Department of Biochemistry and Molecular Biology headed by Professor Susanne Mandrup are publishing a paper entitled «Browning of human adipocytes requires KLF11 and reprogramming of PPAR super-enhancers» in the January 1 edition of the scientific journal
Genes & Development that describes their
results from working with «brite» fat cells.
Balancing Act In the hope of minimizing the number of people forced to cope with incidental findings, the American College of Medical Genetics and Genomics (ACMG) in 2013 proposed regularly returning
results on 56
genes from comprehensive genetic tests.
Until now, the data and test
results for this ongoing work have all come
from preexisting, online digital data sets of
gene expression
from patients with different kinds of infections — not
from current patients.
The
results from the study also showed that
genes that increase the risk for cancer and diabetes, or are important for the immune response or sperm quality, are affected by smoking.
Another possibility is harvesting cells
from an egg that is stimulated to divide as if it were fertilized; the
resulting cells, lacking half the usual
genes, could be closely matched to a wide variety of recipients.
Each Pm3 allele in the four new lines displayed the same activity as in the parental line, which
results in increased overall activity, since it came
from two different
gene variations.
Results from the Sequencing the Legends project are still being processed but indicate that the Bos taurus
genes lurking in the Brahman genome may have been selected for important production traits associated with fertility, growth and temperament.