Sentences with phrase «genetic animal models of disease»
A unique strength of the TNC is our ability to study analogous phenotypes in rare genetic populations and the corresponding genetic animal models of disease.
http://www.childrenshospital.org/ Not exact matches
The identification of these genetic defects has fed back to create ever more realistic animal models of the diseases, as mentioned earlier for Huntington's disease.
«Drug candidate stops extra bone growth in animal model of rare, genetic disease.»
The most important advancement in medicine in the last 25 years was the development of genetic modeling in animals, enabling us to figure out how fundamental mechanisms of physiology and disease work, such as in bone loss.
The discovery was made by developing a mouse model of the disease that enabled researchers to track which of 15 genetic groups — or subclones — of myeloma cells spread beyond their initial site in the animals» hind legs.
Dr. Tarazi studies the behavioral, genetic, molecular, and cellular mechanisms that mediate the actions of dissimilar psychotropic drugs by using animal models that mimic the core symptoms of different neuropsychiatric diseases.
We have learned a fair amount from the neurologic genetic diseases, but we and others also studied these cells in the laboratory as well as in animal models of brain injury.
His lab develops isogenic human pluripotent stem cells and transgenic animals to model disease, with the goal of delineating novel approaches to influence outcomes for Huntington disease (HD) and Fragile X Syndrome (FXS), the most common genetic causes of dementia and intellectual disability, respectively.
To build upon the encouraging early discoveries, Helmsley renewed and expanded its Crohn's funding for the Institute in 2013 to begin new work with three major aims: 1) continue studies of individual genes to determine how genetic differences between Crohn's patients and healthy individuals contribute to the disease; 2) evaluate promising small molecules in disease - relevant studies and prioritize insights from genetics to help develop novel therapeutics; and 3) begin basic experimentation in animal models with Crohn's disease to provide the data necessary to begin testing new therapies in humans.
The Jackson Laboratory Research scientist / Animal models of human disease, Mouse Mutant Resource, Genetic Resource Science 2006 - present
Her address, «A New Medical Research Model: Advancing Human and Animal Health Humanely,» will detail the concept of a new research model predicated on a meaningful commitment by both medical and veterinary researchers to work cooperatively together to address disease and disorders in humans and animals — evaluating genetic and environmental risk factors, sensitive diagnostic indicators and novel theraModel: Advancing Human and Animal Health Humanely,» will detail the concept of a new research model predicated on a meaningful commitment by both medical and veterinary researchers to work cooperatively together to address disease and disorders in humans and animals — evaluating genetic and environmental risk factors, sensitive diagnostic indicators and novel theramodel predicated on a meaningful commitment by both medical and veterinary researchers to work cooperatively together to address disease and disorders in humans and animals — evaluating genetic and environmental risk factors, sensitive diagnostic indicators and novel therapies.