Sentences with phrase «genetic background on»

She likes educating owners about the effects of their pet's past experiences and genetic background on behavior.

Not exact matches

Last November, an hour and a half into a rambling luncheon talk to the faculty, Pres. Lawrence damaged Rutgers and nearly destroyed his own career by uttering the pernicious statement that blacks lack the «genetic, hereditary background to have a higher average» on college entrance exams.

@cw You've just committed a genetic fallacy by discrediting and organization based on its religious background rather than the substance.

Therefore, it would be necessary to gather more data on the range of variability that can be expected under a broader range of genetic backgrounds and in interaction with biotic and abiotic stressors.

Whatever their genetic background, babies start out using both hands interchangeably, and according to Wilmot, it's important that they have this opportunity to develop strength on both sides.

Anonymous donors are matched as closely as possible for the criteria specified by the intended parent (s) based on such criterion as ethnic background, physical traits, and genetic history.

Even small projects with other countries contribute important information on how genetic backgrounds and cultural factors such as diet affect cancer development, he adds.

We also know that this occurs on the background of hundreds of genetic differences that influence predisposition.

Even patients with identical genetic backgrounds could experience different clinical outcomes based on their DNA features that activate genes differently.

So I clicked on it: «Because genetic association studies are generally performed in populations of a particular ethnic background [European, Asian, African], we can not know whether the associations will also apply to those of a mixed background.

We found that the genetic background had a major influence on whether or not weaker mutations would confer drug resistance, and in these cases many different cells adapted in a wave.

«Then, based on the patient's genetic background, we would know what might be the best drug combination,» Tang clarifies.

This webinar will explore recent progress and future directions in translational and clinical efforts centered on checkpoint modulators and combination therapies matched to the molecular profile of individual tumors and the genetic background of patients.

«It's going to vary based on your sex, your genetic background.

This spontaneously arising mutation has been maintained on a mixed genetic background (C57BL / J × C3Heb / FeJ - a / a × CD1) but recently has been backcrossed onto the FVB / NJ strain (57).

SynBioWatch, a collaboration of several nongovernmental organizations (NGOs) that monitors «next - generation genetic engineering,» posted the Gene Drive Files on its website with a camouflage background, and several of its members weighed in.

The phenotype summarized above is for the parental line: Gad2 - IRES - Cre knock - in mice on a mostly C57BL / 6; 129S4 genetic background (Stock No. 010802).

It should be noted that the phenotype of this C57BL / 6J - congenic line (Stock No. 028867 Gad2 - IRES - Cre knock - in (C57BL / 6J)-RRB- could vary from that originally described for mice on other genetic backgrounds.

Gladstone was a great fit for me, especially with its background in developmental and translational biology and Bruce's research focus on cutting - edge technologies to model genetic disease and find novel therapies for treating them.

They discovered that giving the mice antibiotics produced very different effects on their gut microbiomes, as well as on their insulin sensitivity, tissue inflammation and related metabolic functions such as blood glucose, depending on the genetic background of the mouse.

In 2010, Gad2 - IRES - Cre knock - in mice on a mixed genetic background (mostly C57BL / 6; 129S4; with black coat color) were sent to The Jackson Laboratory Repository.

The meeting will give the opportunity to update information on techniques and models in transgenesis and genetic engineering.It is intended for Master, PhD and medical students with a background in molecular biology and genetics as an introduction to future work in these rapidly developing areas of research.

2) If ES cell clones are not available from the IKMC / IMPC resource, mouse models will be generated using genome editing approaches such as CRISPR / Cas9 nuclease technology (on C57BL / 6N genetic background only) and may cover constitutive knock - outs or point mutations.

ES cell derived models will be generated on a C57BL / 6N genetic background.

Based on studies reporting higher insulin resistance throughout childhood in females, the authors concluded a genetic background of their Gender Insulin Hypothesis.

BACKGROUND The aim of the present study was to explore risk variants for coronary artery disease (CAD) and to evaluate their joint effects (quantified by genetic risk score; GRS) on the

The technical evaluation of projects may require the provision of additional data such as information on the genetic modification of your mutant mouse line if applicable (e.g. affected gene, MGI ID of the gene, type of mutation, ES - cell line used, genetic background (e.g. number of backcross generations), safety level, description of DNA modification, vector, remaining non-recipient DNA, donor organism), mutant phenotype (s), special housing or care requirements, current sanitary status, and intellectual property rights (who generated the mouse line, owner of the mouse line)

We are now using these models to study the gene function and complex mechanisms underlying disease pathways, with a focus on genetic background effects, genetic modifiers and interaction partners.

Mutant mice maintained on a genetic background containing a contribution from C57BL / 6J have the potential to harbor a loss - of - function mutation in the nicotinamide (NAD) nucleotide transhydrogenase gene (Nnt, Chromosome 13).

In addition, we are studying genetic background effects on onset and progression of ALS symptoms in the mouse model in hopes that these will provide novel targets for therapy.

«We went looking for genomic abnormalities of ALL specifically in Asians because of their unique genetic background and also the paucity of studies focusing on this population despite the fact that half of children with leukemia worldwide are in Asia.

Counsel patients or others on the background of neurological disorders including risk factors, or genetic or environmental concerns.

Despite the availability of new genome editing techniques, many genetically modified lines are maintained on a mixed genetic background; particularly those developed using ES cells.

We then monitored mammary tumour incidence and progression in this mouse line on Slc6a14 + / + and Slc6a14 − / − genetic backgrounds.

28.04 % of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal behavior (1360/4850)

In previous studies, TERT - / - mice have been generated on either a C57BL / 6J or a 129 / C57BL / 6J mixed genetic background strain, both of which have «very heterogeneous and unusually long telomeres,» again raising the possibility that any developmental abnormalities might be due to subpopulations of stem cells with critically - short telomeres.

The NIH Neuroscience Blueprint has established three centers in the USA for the generation of genetically modified mice expressing Cre recombinases in the nervous system on the C57BL / 6 genetic background.

My research emphasis is on the agronomic performance of robust biofuel and forage crops of diverse genetic backgrounds including switchgrass, sorghum, alfalfa and other biomass crops.

The specificity of CRISPR - Cas9 will depend on each individual mutation and the donor's genetic background.

Based on differences in imputed nsSNP allelic frequencies in different genetic backgrounds, likelihood measurements were calculated for European relative to African genetic backgrounds, with distinct patterns emerging as a function of genetic background.

The research focuses on whether there is a single critical period in development for susceptibility and how genetic backgrounds can influence the outcome.

Dr. Weston A. Price was a dentist who studied the effects of diet on dentition and found that those who ate traditional diets had far better teeth, and excellent health (no heart disease, autoimmune conditions, or obesity) compared with counterparts with similar genetic background who ate Western diets.

The aforementioned sedans are undeniably speedy and dynamically impressive — but at the end of the day, the M5 isn't much more than a 528i on steroids, the S6 is an A6 that has undergone a complicated heart transplant via Sant» Agata Bolognese, the CTS - V and the IS - F both have relatively humble genetic backgrounds, and the E63 AMG started life on the same assembly line as 75 percent of the German taxi population.

Both cats and dogs vary somewhat by their breed, size and genetic background, just like in people, practically the only difference is that they walk on all four legs, and we (as people) walk on two legs.

The study followed more than 1,600 dogs from specific breeds for a number of years, gathering information on medical history, genetic background, personality, and diet.

Assigning carrier risk to both parents falsely places selective pressure against dogs based on their matings, and not their proven genetic background.

Many owners don't have the resources or know - how to prove their dogs» genetic backgrounds, and a recent study by the Maddie's Shelter Medicine Program demonstrated that even shelter workers and other dog experts frequently misidentify breeds based on their appearance.

Similar to canine diabetes, the incidence rate of type 1 diabetes in people is rising (73), a trend that has been explained on the basis of increased contacts with adverse environmental factors acting on a background of complex genetic factors (74).

Other dogs might have a genetic background that tunes their metabolism to a more moderate rate, so that their diet and exercise regimen have a much greater effect on their weight.

It depends on your dog's background, the training he has had, and even his genetic makeup.