Sentences with phrase «genetic circuitry»
"Genetic circuitry" refers to the complex network of genes and molecules inside living organisms that work together to control various biological processes. It is like an intricate wiring system that regulates how cells behave and function. Full definition
Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy Proc Natl Acad Sci U S A. 2013 Jun 11; Authors: Sen A, Dimlich DN, Guruharsha KG, Kankel MW, Hori K, Yokokura T, Brachat S, Richardson D, Loureiro J, Sivasankaran R, Curtis D, Davidow LS, Rubin LL, Hart AC, Van Vactor D, Artavanis - Tsakonas S
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His work on multi-objective optimization (Pareto optimality) and cost - benefit analysis in evolution has led to deep, predictive insights into genetic circuitry and its modular architecture.
Sophisticated genetic circuitry spliced into cells could lead to cancer therapies, tissue generation on demand
As genetic circuitry shapes up, scientists hope the new device will make it easier for them to program cells to do things such as watch for disease, monitor pollution, or even turn on medicine output.
Scientists have tried to extend this to mammalian cells to create genetic circuitry that can help detect and treat human diseases.
Moreover, as biology increasingly expands to include synthetic approaches to building new genetic circuitry, Alon's motifs are providing the guiding design principles for the new field of synthetic biology.
«As we better understand the underlying genetic circuitry that orchestrates development of a particular kind of stem cell into a specialized cell type, we should be able to manipulate it for such purposes.»
Instead of trying to design every aspect of the genetic circuitry involved in a particular trait down to the last DNA letter, his idea is to come up with a relatively rough design, create lots of variants on this design and select the ones that work best.
Scientists designed the bacteria by adding 18 new genes to their genetic circuitry, including thousands of DNA bases that code for light sensor proteins that respond to red, green, or blue light.
Individual freedom and social responsibility may sound like humanistic concepts, but an investigation of the genetic circuitry of bacteria suggests that even the simplest creatures can make difficult choices that strike a balance between selflessness and selfishness.
«Understanding the genetic circuitry that orchestrates development of each specialized cell type,» Singh added, «should enable us to manipulate it for our own purposes.»
Now researchers led by the Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute have managed to induce a ground state by rewiring the genetic circuitry in human embryonic stem (ES) cells and in adult cells that have been induced into a pluripotent state.
My laboratory uses the zebrafish to elucidate the genetic circuitry that controls regeneration of two organ systems in response to injury: the adult heart and the caudal fin appendage.
My research centers on identifying and understanding the genetic circuitry that defines organ regeneration, with a particular focus on miRNAs.
Cells use this genetic circuitry to detect signals, to process information, and to make decisions.
The new idea is synthetic biology, an effort to rewire the genetic circuitry of living organisms.