Sentences with phrase «genetic culprit»

Huntington's is one of the few diseases with a straightforward genetic culprit: One hundred percent of people with a mutated form of the Huntingtin (HTT) gene develop the disease.

In papers published online today in Neuron, Rademakers's team and another group led by Bryan Traynor, a neurologist specializing in ALS at the National Institute on Aging in Bethesda, Maryland, identify the same genetic culprit, mutations in an obscure gene called C9ORF72.

but it could also be possible that there are certain genetic culprits, for instance defects in specific enzymes found to be important related to congenital disorder of glycosylation (carbohydrate - deficient glycoprotein syndrome).

For two decades, scientists have known some of the genetic culprits that drive lung cancer growth, including mutations in a gene called KRAS, which are present in one - third of patients with smoking - related lung cancers, according to Baylin.

This approach will allow us to very quickly find the genetic culprit,» says Leroy Hood, a geneticist at the Institute for Systems Biology in Seattle.

This genetic culprit was revealed by a second and little - heralded phase in the Human Genome Project, and it comes five years after a rough draft of the entire human genome was announced.

Even before they determine the genetic culprit in a disease, however, scientists can use its SNP pattern to identify those who have the genetic signature of risk for that disease.

The mechanisms behind this were unclear, but now scientists think they may have caught the genetic culprit in action.

Although only about 10 % of prostate cancer victims inherit the disease, the genetic culprit could reveal broader clues about how prostate cancer wreaks its damage.

The idea is to sequence the 1 % of the patient's DNA that codes for protein — the «exome» — then sift the data for the genetic culprit behind the disease.

The researchers, who previously identified NOTCH1 as a genetic culprit in human CAVD, created mice that had shorter telomeres and were also missing one copy of the NOTCH1 gene, since mutation of NOTCH1 alone failed to induce valve disease in mice.

Cause of Hereditary Lung Disease Found Scientists at Johns Hopkins identified the genetic culprits that trigger a hereditary form of a fatal lung disease.

That evidence seemed to point toward a genetic culprit, with suspect genes inherited from an autistic child's parents.

We are zooming in on the genetic culprits of IBD,» he said in an institute news release.