«It is possible that we in modern societies have more individual freedom to express our genetic predispositions because social and normative influences are more relaxed, and this leads to
the genetic differences among us explaining more of the reproductive patterns,» said Dr Bolund.
Such uncertainties may point to subtle, as - yet - undiscovered
genetic differences among TB strains.
Careful genetic analysis not only confirmed long - standing suspicion that Y. pestis was the microbe responsible for the plague, but also found slight
genetic differences among bacteria from various remains at the site — suggesting that even as it killed millions, the bacterial strain itself was dying off.
Antigenic and
genetic differences among the DENV types influence disease outcome, vaccine - induced protection, epidemic magnitude, and viral evolution.
Japan, China, and the SNP Consortium — a public - private group seeking
genetic differences among different versions of the human genome — are also adding to the pot.
For comparison,
the genetic differences among giraffe species are at least as great as those between polar and brown bears.
Another thing the team didn't consider was
genetic differences among individuals: Some monkeys are naturally more susceptible to adversity whereas others are more resilient, he says.
But it has been difficult to determine just how much the invaders — Anglo - Saxons from Europe's North Sea coast — contributed because of the small
genetic differences among European groups.
Cancer researchers are just beginning to investigate the extent and significance of
genetic differences among tumor cells — either cells within a discrete tumor or between a primary tumor and metastases in other parts of the body.
Other chapters apply this to the genetics of immune systems, the evolutionary benefits of sexual reproduction,
genetic differences among human populations, the origin of life and more.
But to get the most out of canine gene hunts, geneticist Elaine Ostrander and her colleagues at the Fred Hutchinson Cancer Research Center in Seattle, Washington, realized that she needed to know the degree of
genetic differences among various breeds.
According to them,
the genetic differences among giraffe species are as great as those between polar and brown bears.
You might even take a biopsy, a small sample of whale flesh, and do a more detailed study of
genetic differences among individual Humpbacks.
«New technologies are allowing us to look at subtle
genetic differences among large groups of study participants.
Kruglyak and his colleagues performed detailed statistical analyses of the data to detect patterns that would reveal
genetic differences among the breeds.
Although differences in the environments in which people live often are suspected when asthma risks among populations differ, the new findings illustrate the importance of also considering
genetic differences among ethnic groups in diagnosing and treating disease, said Esteban Burchard, MD, professor of bioengineering for the UCSF School of Pharmacy and the senior scientist for the study.
A new study has suggested that
the genetic differences among giraffe species are as great as those between polar and brown bears.
He is currently a postdoctoral fellow in Pedro Beltrao's lab at the European Bioinformatics Institute (EMBL - EBI), Wellcome Genome Campus, Cambridge, where he is developing models to predict the impact of
genetic differences among different strains of the model gut bacterium Escherichia coli, in collaboration with microbiologist Nassos Typas (EMBL, Heidelberg).
Not exact matches
And the
difference in
genetic divergence
among MODERN MAN around the world and the
genetic divergence seen in apes blows a HOLE in theory that we evolved from apes.
Past studies have found IDH mutations to be
among the most common
genetic differences seen in patients with iCCA, but how they contribute to cancer development was unknown going into the current effort.
«In order to detect the
genetic variation, we examined the
differences in the
genetic heritage
among different populations.
This visual abstract depicts how
genetic variants enriched in population specific signals of natural selection and,
among Europeans, of Neandertal ancestry play a major role in the
differences in transcriptional responses to inflammatory and infectious challenges observed between human populations.
The short answer is that there is no biological basis for «race» as we know it, but
among populations there can be small but measurable
genetic differences.
Such regions defy elucidation via conventional sequencing approaches, which simply can not detect extremely subtle
genetic differences found hidden
among the «mirrors.»
Research has identified sex and
genetic differences in gastrointestinal, cardiovascular and neurological systems,
among others.
The investigators measured four Aβ peptides and found that no significant
differences in plasma levels of any of the Aβ peptides were found
among the three
genetic groups.
Previous studies have suggested,
among other things, that
differences in dogs» ability to communicate are associated with variations in the
genetic material located close to the gene that codes for the oxytocin receptor.
This adaptation, unique
among vertebrate life, also makes them a useful species for studying
genetic differences in physical form and performance.
The new
genetic adaptations, some 2,000 in total, are not limited to the well - recognized
differences among ethnic groups in superficial traits such as skin and eye color.
Vance and van der Walt looked for
genetic differences in mitochondrial DNA
among nine lineages of European origin.
Among them were sharp
differences between the three groups in
genetic regions involved in smell and taste — suggesting that each population's senses had adapted to the new smells and foods they encountered.
Genetic differences between two very similar fungi, one that led to Quorn ™, the proprietary meat substitute, and another that ranks
among the world's most damaging crop pathogens, have exposed the significant features that dictate the pair's very different lifestyles.
To find the gene itself, Yoshiura and his colleagues looked for
genetic differences in this region
among 64 Japanese with dry earwax and 54 Japanese with wet earwax.
Fourth, disease network analysis ultimately provides a mechanistic basis for defining phenotypic
differences among individuals with the same disease through consideration of unique
genetic and environmental factors that govern intermediate phenotypes contributing to disease expression.
They account for about half of all
differences in intelligence
among people, so half is not caused by
genetic differences, which provides strong support for the importance of environmental factors.
$ 1,500 «All in the family» Shallow shotgun metagenomic analysis of up to four fecal samples (furry family members also ok), including mapping to reference genomes and comparing profiles of
genetic similarities and
differences among different family members.
Because people exposed to Ebola show phenotypic variability in susceptibility to infection and disease severity, it is likely that human
genetic variation contributes to individual immunity and infectivity and that host
genetic differences are one factor
among many that interact to influence the infection.
To compare the breeds, the researchers analyzed the DNA samples from the cheek - swabs for subtle
differences in
genetic signposts, called microsatellite loci,
among the dogs.
They sometimes study disorders that are not inherited at all, which are due to somatic mosaicism - a
difference in
genetic composition
among cells in an individual.
The last decade has witnessed an explosion of human
genetic analyses in different world populations, highlighting similarities and
differences among studied groups in diverse geographic areas.
Whether most of the
genetic differences that influence individual predispositions to common diseases are widely shared within populations, or whether they are rare or unique events in an individual family has been vividly debated
among scientists.
Tumor heterogeneity, i.e., the
differences between cells within one tumor,
among different tumor lesions of the same patient, or between patients even if the tumors are of similar
genetic signatures, provides major challenges for future therapy.
The
genetic basis of morphological
differences among species is still poorly understood.
Genetic variation in HDAC4
among the women was linked to a lower level of HDAC4 gene activity and
differences in their ability to respond to and recover from fear, and also
differences in «resting state» brain imaging.
«For this reason, it is thought the observed
differences in nose shape
among populations are not simply the result of
genetic drift, but may be adaptations to climate.»
No significant
differences in
genetic diversity were observed
among populations by microsatellite markers with HE ranging from 0.597 to 0.612 and low, but significant,
genetic differentiation
among populations (FST = 0.019, P = 0.001).
Even
among a litter, where the parents are the same and there is little
genetic variability, there are
differences.
In a recent study published in the Public Library of Science - Biology, researchers have found that
differences among dog breeds can be defined through only seven
genetic regions, making each breed much closer in character that previously thought.
For example, some have found significant
differences between children with divorced and continuously married parents even after controlling for personality traits such as depression and antisocial behavior in parents.59 Others have found higher rates of problems
among children with single parents, using statistical methods that adjust for unmeasured variables that, in principle, should include parents» personality traits as well as many
genetic influences.60 And a few studies have found that the link between parental divorce and children's problems is similar for adopted and biological children — a finding that can not be explained by
genetic transmission.61 Another study, based on a large sample of twins, found that growing up in a single - parent family predicted depression in adulthood even with
genetic resemblance controlled statistically.62 Although some degree of selection still may be operating, the weight of the evidence strongly suggests that growing up without two biological parents in the home increases children's risk of a variety of cognitive, emotional, and social problems.
In addition, behavior
genetic studies suggest
genetic factors contribute to temperamental
differences among children and influence the association between temperament and child outcomes.23 Children with tendencies toward negative emotionality and poor self - regulation may be especially difficult to provide optimal care for, and their parents appear particularly likely to use less firm control over time, 24 but they are also the very children who especially need calmly - persistent caregiver efforts.