Sentences with phrase «genetic diseases in animals»

OFFA receives funds and offers grants for research into genetic diseases in animals.

Researchers already have used it to fix genetic diseases in animals, to combat viruses and to sterilize mosquitoes.

In the four years since CRISPR has been around, researchers have used it to fix genetic diseases in animals, combat viruses, sterilize mosquitoes and prepare pig organs for human transplants.

to encourage and finance research in orthopedic and genetic disease in animals and 4.)

Not exact matches

Where is the clear line in a progression from (1) using animal insulin to treat diabetes, to (2) using gene remodeling techniques to grow insulin in a host bacterium that will reproduce rapidly and from which a plentiful supply of insulin can be harvested, to (3) genetic surgery to replace the defective gene in a person diagnosed as diabetic, to (4) genetic surgery immediately after fertilization in order to replace the defective gene and alter the germ cells which would otherwise have transmitted the disease to one's offspring?

Last September The War Cry noted that the Human Fertilisation and Embryology Authority (HFEA) had agreed in principle to allow the mixing of animal and human genetic material for research into incurable diseases and that the resultant 99.9 per cent human mixture would be human bits, not human beings.

Dioxin is carcinogenic and has been linked to birth defects, skin disease, liver disease, immune system suppression & genetic damage in lab animals.

To better understand their findings, the team examined the animal model for APS1 (i.e. mice with the same genetic defect as human patients with the syndrome) and found that male mice spontaneously developed an inflammatory disease in their prostate glands — a so - called prostatitis — and reacted to transglutaminase 4.

Preventing the transmission of inherited genetic diseases, and increasing food production rates in farmed animals are two potential applications of genome editing technologies that require urgent ethical scrutiny, according to a new report by the Nuffield Council on Bioethics.

«Drug candidate stops extra bone growth in animal model of rare, genetic disease.»

The new report describes experiments in mice showing how genetic variation in a host animal shapes the microbiome — a rich ecosystem of mostly beneficial microorgannisms that resides in the gut — and sets the table for the onset of metabolic disease.

The most important advancement in medicine in the last 25 years was the development of genetic modeling in animals, enabling us to figure out how fundamental mechanisms of physiology and disease work, such as in bone loss.

The discovery was made by developing a mouse model of the disease that enabled researchers to track which of 15 genetic groups — or subclones — of myeloma cells spread beyond their initial site in the animals» hind legs.

Unless an animal can recombine the DNA they already have, they will produce an offspring with an identical set of chromosomes, in which any genetic weakness, such as disease susceptibility or physical mutation, would have no chance to be overridden by outside genetic material from a mate.

The new report describes experiments in mice showing how genetic variation in a host animal shapes the microbiome — a rich ecosystem of mostly beneficial microorganisms that resides in the gut — and sets the table for the onset of metabolic disease.

In the paper, the authors stressed that understanding the genetic makeup of these molluscs is important because many «freshwater snails are intermediate hosts for flatworm parasites and transmit infectious diseases» to humans and other animals.

We have learned a fair amount from the neurologic genetic diseases, but we and others also studied these cells in the laboratory as well as in animal models of brain injury.

To build upon the encouraging early discoveries, Helmsley renewed and expanded its Crohn's funding for the Institute in 2013 to begin new work with three major aims: 1) continue studies of individual genes to determine how genetic differences between Crohn's patients and healthy individuals contribute to the disease; 2) evaluate promising small molecules in disease - relevant studies and prioritize insights from genetics to help develop novel therapeutics; and 3) begin basic experimentation in animal models with Crohn's disease to provide the data necessary to begin testing new therapies in humans.

A unique strength of the TNC is our ability to study analogous phenotypes in rare genetic populations and the corresponding genetic animal models of disease.

We are currently employing our new genetic tools for mast cell - specific inactivation of loxP - flanked genes and for inducible ablation of mature mast cells in adult animals to clarify the roles mast cells play in neoplastic disease.

Dioxin is carcinogenic and has been linked to birth defects, skin disease, liver disease, immune system suppression & genetic damage in lab animals.

Variation in genetic background may alter expression of the disease allele in affected animals, thus accounting for variation in phenotypic expression of the disease.

Her address, «A New Medical Research Model: Advancing Human and Animal Health Humanely,» will detail the concept of a new research model predicated on a meaningful commitment by both medical and veterinary researchers to work cooperatively together to address disease and disorders in humans and animals — evaluating genetic and environmental risk factors, sensitive diagnostic indicators and novel therapies.

It was established later (Johnson et al, 1980) that the form of the disease found in Bedlingtons terriers was apparently caused by the presence of an autosomal recessive gene in affected dogs - it is a genetic disorder and in order for the condition to develop in a dog / bitch a copy of this defective gene must have been passed to the affected animal by both parents, i.e. the affected dog must have two «copies» of the defective gene in its body cells.

However, such participation may provide veterinarians and researchers with additional information and a better understanding of canine diseases, which could ultimately influence the course of treatment or genetic testing to help your dog and other animals in the future.

A responsible breeder will guarantee their puppies for any genetic diseases that may occur or against show - ring disqualifications in an animal intended for showing or breeding.

However, these guarantees last for only a year while majority of genetic diseases found in dogs materialize when the animal is over a year old.

In an effort to limit or eradicate genetic ocular diseases, the OFA (Orthopedic Foundation for Animals) organization collect data on breeding dogs and issues certificates determining a dog's fitness for breeding.

According to the Morris Animal Foundation announcement, Dr. Meurs is a leader in the field of genetics of cardiac disease in companion animals, with a proven track record of successfully identifying the genetic basis for numerous canine and feline cardiac diseases.

Breeding animals should be examined annually, even after they have stopped breeding, in order to look for genetic eye diseases.

These commercial breeding operations are inherently exploitive not only of the animals trapped in inhumane breeding conditions, but also of the public that purchase over-priced pets, many of whom have diseases, genetic defects and behavior problems due to poor breeding practices, inadequate nutrition and lack of socialization and veterinary care.

These animals consequently receive below standard food, minimal if any veterinary care, and inadequate shelter which, combined with the inbreeding prevalent in puppy mills, produce animals with genetic diseases and abnormalities.

The new company, Zoetis, will build on the leadership of Pfizer Animal Health in the discovery, development, manufacture and marketing of a diverse portfolio of animal vaccines, medicines, biopharmaceuticals, diagnostics and genetic tests to prevent and treat disease in livestock and companion anAnimal Health in the discovery, development, manufacture and marketing of a diverse portfolio of animal vaccines, medicines, biopharmaceuticals, diagnostics and genetic tests to prevent and treat disease in livestock and companion ananimal vaccines, medicines, biopharmaceuticals, diagnostics and genetic tests to prevent and treat disease in livestock and companion animals.

The Veterinary Genetics Laboratory, established in the 1950s as a blood - typing laboratory to verify parentage for cattle registries, has pioneered DNA - based identification techniques to provide pedigree validation, forensic services, diagnostic tests and genetic disease research in large animals, pets and wildlife species.

His research and clinical interests throughout his career have been focused on improving the ability of veterinarians to detect and prevent genetic and infectious diseases in companion animals through the development of multiple novel diagnostic tests and vaccines.

Parents should have their hips and elbows x-rayed, clear of hip and elbow dysplasia by the Orthopedic Foundation of Animals (OFA) or the Institute for Genetic Disease Control in Animals (GDC) and be issued certification numbers.

The Institute for Genetic Disease Control in Animals (GDC) is an open registry.

ACVO diplomats are trained to accurately diagnose and treat eye diseases in dogs and other animals, screen animals for genetic eye diseases, offer breeding advice regarding actual or presumed genetic eye disorders, and offer micro-surgical options for the treatment of certain conditions.

The major health registries are the Orthopedic Foundation for Animals; PennHip; the Canine Eye Registration Foundation, and the Institute for Genetic Disease Control in Animals.

Zoetis, which manufacturers drugs and vaccines for small and large animals, noted that Dr. Goldstein's research and clinical interests have focused on «improving the ability of veterinarians to detect and prevent genetic and infectious diseases in companion animals through the development of multiple novel diagnostic tests and vaccines.»

Generally, Lascelles notes, companion animal disease models better reflect the complex genetic, environmental and physiological influences in human diseases, as opposed to the traditional rodent models.

On Saturday, Jan. 15, at TNAVC, Pfizer will participate in a luncheon announcing its financial and scientific support of the Morris Animal Foundation's Canine Lifetime Health Project, the largest and most comprehensive study ever conducted in dogs to identify genetic, environmental and nutritional risk factors for the development of cancer and other diseases.

Cataracts, genetic diseases and other causes are often the root of sight loss in older animals.

Does no genetic testing; ignorantly breeds defective animals or those which are carriers, thus, perpetuating disease in breed

Generally speaking, dog breeders are keen to participate in efforts to identify the genetic causes of disease in their favorite pooches, with the hope of improving the health and quality of life for their animals.

Topics such as the effects of processed pet foods on the health of companion animals, annual vaccination of dogs and cats, corporate sponsorship of academic chairs and professorships, and the British Veterinary Associationâ $ ™ s focus on genetic diseases of dogs are so diverse and so complex that it is not possible to adequately discuss them all in a letter.

The biggest factor in the development of heart disease is the individual animal's genetic make - up.

The Orthopedic Foundation for Animals (OFA) was founded in 1966 and its mission is «to improve the health and well being of companion animals through a reduction in the incidence of genetic disease.Animals (OFA) was founded in 1966 and its mission is «to improve the health and well being of companion animals through a reduction in the incidence of genetic disease.animals through a reduction in the incidence of genetic disease.»

Some of these animals are in - bred, passing on genetic diseases.

While elimination of genetic diseases is a worthy goal, the converse is that excessive culling of animals from the gene pool may have the equally deleterious effect of limiting the gene pool in the breed.