Sentences with phrase «genetic epidemiology studies»

Mediated by this role, Sarah has established collaborations with researchers from a range of countries enabling the development of a network to support global P. vivax genetic epidemiology studies.

Not exact matches

I continued working at the interface of science and epidemiology, first with Genaissance Pharmaceuticals, a New Haven - based pharmacogenomics company, where I was involved in the fascinating study of human genetic variation and population genetics.

«The type of inflammation seen in psoriasis is known to promote insulin resistance, and psoriasis and diabetes share similar genetic mutations suggesting a biological basis for the connection between the two conditions we found in our study,» said the study's senior author Joel M. Gelfand, MD MSCE, a professor of Dermatology and Epidemiology at Penn. «We know psoriasis is linked to higher rates of diabetes, but this is the first study to specifically examine how the severity of the disease affects a patient's risk.»

Their traditionally low - budget science, which needs only pencil and paper to tally shared traits in the classical twin studies, has entered the high - tech world of genetic epidemiology, which traces the power of genes to influence the health of populations.

Lead author of the study, Dr Simone Ribero, a dermatologist from the Department of Twin Research and Genetic Epidemiology at King's, said: «For many years dermatologists have identified that the skin of acne sufferers appears to age more slowly than in those who have not experienced any acne in their lifetime.

To investigate the issue, a team led by Tracey Weissgerber, PhD and Vesna Garovic, MD (Mayo Clinic) analyzed information on 919 men and 1477 women from 954 sibships who participated in the Genetic Epidemiology Network of Arteriopathy study, which examined the genetics of hypertension in white, black, and Hispanic siblings.

Dr Lavinia Paternoster, Senior Lecturer in Genetic Epidemiology from Bristol Medical School: Population Health Sciences, who initiated the study, said: «This study brought together two European birth cohorts, PIAMA, from the Netherlands and ALSPAC (or «Children of the 90s») from Bristol.

Dr Louise Wain, Associate Professor in Genetic Epidemiology who led the team of analysts at the University of Leicester added: «The research shows the value of the UK Biobank study and of «big data» for making discoveries that will improve health.

Fallin's interests are in applying genetic epidemiology methods to studies of neuropsychiatric disorders including autism, Alzheimer's disease, schizophrenia, and bipolar disorder and in developing applications and methods for epigenetic epidemiology, particularly as applied to mental health and development.

But other scientists cautioned that other explanations beside spontaneous genetic mutation could also account for the study's results.For example, said Dr. Ann Pulver, director of the epidemiology and genetics program in psychiatry at Johns Hopkins University, «It may be that the fathers of schizophrenics have unusual characteristics that delay reproduction.»

For example, detecting population substructure is important in case - control studies in genetic epidemiology and can provide valuable information in forensic science.

Additionally, she leads or co-leads several other collaborative studies, including the Population Architecture Using Genetics and Epidemiology (PAGE) Study and the Colorectal Transdisciplinary (CORECT) Study, which is a part of the Genetic Associations and Mechanisms in Oncology (GAME - ON).

Project: Genome - wide Association in Primary Open Angle Glaucoma: The Blindness in Glaucoma Genetic Epidemiology Relative Risk Study

Genetic epidemiology is a discipline takes care of studying the role of genetic factors and their interaction with environmental factors in the aetiology of human dGenetic epidemiology is a discipline takes care of studying the role of genetic factors and their interaction with environmental factors in the aetiology of human dgenetic factors and their interaction with environmental factors in the aetiology of human disease.

Genetic epidemiology combines the genetic method with the epidemiological method to study genetic variation in human populations and their relation with normal and pathological phenotypical cGenetic epidemiology combines the genetic method with the epidemiological method to study genetic variation in human populations and their relation with normal and pathological phenotypical cgenetic method with the epidemiological method to study genetic variation in human populations and their relation with normal and pathological phenotypical cgenetic variation in human populations and their relation with normal and pathological phenotypical changes.

ApoE as a major causative factor and therapeutic target in Alzheimer's disease and other neurodegenerative disorders; small - molecule structure correctors to convert apoE4 to apoE3 and reverse the detrimental effects of apoE4 on mitochondria and the cytoskeleton; small - molecule protease inhibitors to block the formation of toxic fragments of apoE4; Plasma lipoprotein metabolism regulation involving apoE and apoB; cholesterol homeostasis modulation by lipoprotein receptors controlling lipoprotein clearance by the liver; Plasma HDL cholesterol (HDL - C) metabolism in the progression of atherosclerosis; the genetic epidemiology of the metabolic syndrome and low HDL - C levels established by the Turkish Heart Study.

The study, «Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study,» This work was supported by the Genetic Associations and Mechanisms in Oncology Network, Genetics and Epidemiology of Colorectal Cancer Consortium, the National Cancer Institute, the National Institute on Aging, the Cancer Research Foundation, the Wellcome Trust, and the National Health and Medical Research Council.

The participants in the study were 1,906 Han Chinese adults in the GenSalt project (Genetic Epidemiology Network of Salt Sensitivity), a large project to identify environmental and genetic factors leading to salt sensiGenetic Epidemiology Network of Salt Sensitivity), a large project to identify environmental and genetic factors leading to salt sensigenetic factors leading to salt sensitivity.

Drawing upon evidence from multiple studies, Professor of genetic epidemiology at King's College London and author of The Diet Myth, Tim Spector said the restrictive nature of highly processed diets which use just a few ingredients is responsible for reducing our microbe diversity — and is making us ill.

These include the latest clinical studies on emerging developments in renal medicine and the highest level of original research studies in therapy and epidemiology of acute and chronic kidney failure, as well as their translational aspects and genetic basis.