Sentences with phrase «genetic factors explain»

Dr. Lacourse claims that genetic factors explain a substantial part of individual difference in physical aggression.

[jounal] Larsson, H. / 2006 / A genetic factor explains most of the variation in the psychopathic personality / Journal of Abnormal Psychology 115: 221 ~ 230

In quantitative genetic models genetic factors explained the majority of the associations between SDP and cognitive and externalizing outcomes.

Not exact matches

How do you explain that all of these genetic mutations resulting from natjural environmental factors all just «happen» to occur in that way?

Genetic factors drive this early overproduction of neurons, Schore explains, but the brain awaits direction from the social environment, or epigenetic processes, to determine which synapses or connections are to be pruned, which should be maintained, and which genes are turned on or off.

The reasons are complex and not entirely clear, but most folks who have studies the problem believe that the obvious socioeconomic factors do not adequately explain it, and it may be partly genetic.

In the past, Dr. Frayling explained, it has been difficult to measure interactions between genetic risk factors and aspects of environment and lifestyle in a systematic way.

Many of the mutations in ASD, Yan explained, result from chromatin remodeling factors, which are involved in dynamically changing the structure of chromatin, the complex of genetic material in the cell nucleus that condenses into chromosomes.

«The results of this study shed light on the great complexity of factors that contribute to the physiological differences between people and allow us to better understand how genetic diseases develop,» explains Maria Gutierrez - Arcelus, first author of this article and member of the Swiss National Centre of Competence in Research Frontiers in Genetics.

Although previous studies have found that a large percentage of hair colour variation is explained by heritable factors, previous genetic studies only identified a dozen or so hair colour genes.

Heritability (how much the risk of a disease is explained by genetic factors) of type 2 diabetes has been estimated to be between 25 and 80 per cent in different studies.

«Inherited genetic factors may have a cumulative effect; therefore, the disease would only appear if a certain number of variants are inherited,» explain researchers.

The new study quadruples the number of known genetic risk factors for Fuchs dystrophy, and helps explain its genetic etiology.

Although the genetic studies indicated that the female offspring were the result of parthenogenesis, researchers have yet to untangle the cellular factors that explain how and why this happened.

«To date, research into resilience has tended to take into account a very extensive range of social, psychological, and even genetic factors that positively influence mental flexibility, such as social support, certain personality traits, and typical behavior patterns,» explained Professor Raffael Kalisch, one of the authors of the current publication and the director of the Neuroimaging Center, a central research platform of the Mainz University Medical Center and the Research Center on Translational Neurosciences.

Dr Veronique Bataille, senior author of the paper and another dermatologist in the Department of Twin Research and Genetic Epidemiology said: «Longer telomeres are likely to be one factor explaining the protection against premature skin aging in individuals who previously suffered from acne.

Much of the correlation between alcohol dependence and ADHD can also be explained by genetic factors.

This can help them to determine whether the correlation between different conditions can best be explained by a person's genetic background giving higher susceptibility to a condition, or whether environmental factors are significant.

The convergence of several factors explains the trend: cheaper genetic sequencing technologies, the discovery of new oncogenes (genes that can cause a normal cell to become cancerous), a new generation of computers and bioinformatics that can analyze vast amounts of data, and a multibillion - dollar effort by researchers inside and outside the pharma industry to develop targeted drugs and companion diagnostics for cancer.

He explains, «Our study shows, for the first time, that we can classify an individual's risk of breaking a bone much more reliably when we take genetic factors into account alongside clinical factors.

«It is now clear that common risk variants fail to explain the vast majority of genetic heritability for any human disease,» they wrote in an essay, arguing that many of the hundreds of GWAS findings to date «stem from factors other than a true association with disease risk.»

They found that C9ORF72 mutations explained about 22 % of familial cases of ALS and 12 % of familial cases of FTD, far more than any of a handful of other genetic risk factors they examined in the same patients.

Three basic mechanisms have been proposed over the years to explain the formation of specific neural circuitry: (1) an elaborate predetermined program encoded genetically in each neuron that unfolds according to rigid and unmodifiable rules, (2) a random process of trial and error in which growing nerve fibers that make the right connections are consolidated and those that fail are reabsorbed and (3) a general program of circuit formation that is brought to completion by an interplay between genetic and extrinsic factors.

«The lack of association between the body type genetic risk score and confounding factors such as diet and smoking provides strong evidence that abdominal adiposity itself contributes to causing Type 2 diabetes and heart disease,» explained Connor Emdin, from the Massachusetts General Hospital.

The researchers looked at several factors that might explain this racial difference, such as whether there were differences in tumor characteristics between black patients and white patients, or differences in a family history of breast cancer — both factors that a doctor must consider before deciding whether a genetic test will likely benefit a particular patient.

«More interesting is that they found no evidence of past cannabis use leading to depression or anxiety — suggesting that increased rates of depression and anxiety in cannabis users may be explained not by their cannabis use but by other environmental or genetic factors.»

These factors would explain why there are no particular genetic mechanisms that cause autism, but instead, individuals with this neurocomputational deficit have their brains functioning improperly.

The answers is yes — studies of genetic history like this one are important because they help explain why blacks and whites often have different genetic risk factors for the same diseases.

Dr. Toal is also of the opinion that our personal skin microbiome is influenced by several genetic and environmental factors, explaining that oil secretion, pH levels, moisturization, and the products we use on our skin help or hurt these bacteria.

When they examined the data, they concluded that the reduction in life expectancy could not be explained by genetic factors, the lifestyle choices or behavior of the patient, the skill of the doctor, or any other variable.

Leah's work explains her belief that a variety of factors, including toxins, a damaged digestive system, vaccines, antibiotics and bad nutrition, along with a person's genetic makeup can result in different illnesses.

Unless we think there are big and important genetic differences across countries, the variation in effort across countries has to be explained by factors that are social constructed and, at least in theory, could be changed.

Dr. Erin Chu, from Embark's veterinary team, reached out to Roberta to explain that Jake has two copies of a mutation in the DNM1 gene: this genotype greatly increases Jake's risk of developing EIC, though like most genetic risk factors, doesn't fully guarantee that he will develop the condition.

In behavior modification, things get more sophisticated, and it is too complicated to explain here what is done, since each behavior problem has roots in the dog's genetic temperament, the dog's history, the people involved, the relationships among the people and the dog, potential medical issues, and environmental factors.

Similar to canine diabetes, the incidence rate of type 1 diabetes in people is rising (73), a trend that has been explained on the basis of increased contacts with adverse environmental factors acting on a background of complex genetic factors (74).

In other words, a heritability estimate tells us that genetic factors play a role in general, but it does not explain why any one of us will experience divorce.

«The gene - environment analysis revealed that early genetic factors were pervasive in accounting for developmental trends, explaining most of the stability and change in physical aggression,» Dr. Eric Lacourse said.

Burgess and Drais propose that child maltreatment is too complex to be explained fully by genetic relatedness alone and cite other reasons for child maltreatment, such as social factors, ecological factors and child traits such as disability and age.

These behaviors appeared to be explained mostly by genetic factors, suggesting that there is a genetic vulnerability for developing antisocial behaviors which may also lead to addictive behaviors such as pathological gambling (Slutske, et al., 2001).

Genetic influences explained more than half of the variance in this externalizing factor in both boys and girls.

For internalizing and externalizing problem behavior it was found that both genetic and shared environmental influences could be modeled by an underlying common factor, which explained variance in problem behavior from early adolescence into adulthood and accounted for stability over time.

In a birth cohort study, risk of psychosis in adulthood was raised by a factor of 4 if the mother, during pregnancy, reported that a baby was unwanted.49 Separation from parents in early life has been found to predict an increased risk of psychosis in genetically vulnerable children, 50,51 and the association between immigrant status and severe mental illness may be at least partially explained by the high rates of early separation in migrant populations.52 Adolescents at high genetic risk of psychosis have also been found to be at increased risk of psychosis in later life if they report adverse relationships with their parents.53