Sentences with phrase «genetic heterozygosity»

This could result in a reduced gene pool and reduced genetic heterozygosity leading to other potential health risks.

Not exact matches

Here, we report the genome sequence of this pathogen and 7,863 identified protein - coding genes, and we show that the majority of clinical isolates possess high levels of allelic diversity, genetic admixture, heterozygosity, and extensive aneuploidy.

It tended toward greater heterozygosity — a mix of gene versions — within individual dogs, maintained genetic diversity in the breed, and therefore lessened the likelihood that bad genes for things like eye disease would match up.

In another study, there was little correlation between current levels of inbreeding or reduced heterozygosity and prevalence of genetic disease [19].

Measurements of observed and expected heterozygosity (Ho and He) and the inbreeding coefficient F are also useful in looking at the genetic makeup of a population.

Whereas human forms of CMS are often caused by compound heterozygosity, low levels of genetic diversity within purebred dog populations make simple recessive alleles more common.

-- We quantified genetic diversity by calculating observed heterozygosity (HO) and Nei's (1978) expected heterozygosity (HE), using the program TFPGA (version 1.3 — Miller 1997).

Estimation of average heterozygosity and genetic distance from a small number of individuals

Reduced allelic diversity and heterozygosity are expected consequences of founder effects, genetic drift, and inbreeding, which are associated with colonization and subsequent small population size (Frankham 1997, 1998).