Sentences with phrase «genetic lesions»
The phrase "genetic lesions" refers to changes or mutations in a person's genetic material. These changes can affect the normal functioning and structure of genes, and may lead to the development of certain diseases or conditions. Full definition
Models of rare cancer subtypes may be nonexistent or underrepresented, and there are no models for many recurrent genetic lesions in human cancer.
cancer.gov
They are also studying whether the nanoparticles can be used with the CRISPR / Cas9 gene - editing technique to treat genetic lesions related to retinal degenerative diseases.
Great strides have been made in the understanding of cancer, and now this work is starting to pay off with multiple drugs targeting many cancerous genetic lesions.
«The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type,» by Mariia O. Yuneva et al., Cell Metabolism, Feb. 8, 2012.
In this fashion, they derive a signal from the tumor cells proportional to tumor mass which arises spontaneously in vivo in the accurate setting of the lung and from the accurate genetic lesions found in human non-small cell lung cancer (NSCLC).
However, for the «complex» patients, new methods or «omics» approaches will be required to identify all pathogenic genetic lesions to inform therapy development.
In Huntington's disease, mice carrying the pathologic genetic variant of the huntingtin gene are being used to understand how this genetic lesion causes degeneration of striatal neurons and to develop novel treatments for the illness.
I. Develop a 3D cancer atlas Create dynamic 3D maps of human tumor evolution to document the genetic lesions and cellular interactions of each tumor as it evolves from a precancerous lesion to advanced cancer.