Sentences with phrase «genetic mechanisms involved»

«Until the genetic mechanisms involved are more clearly understood, it seems prudent for veterinarians to advise owners of epileptic dogs that:

the definition of genetic mechanisms involved in the pathogenesis of chronic airways infection to better understand individual risk determinants in Cystic Fibrosis;

Not exact matches

There are of course many mechanisms that are involved in these concepts, such for example as genetic assimilation established by Waddington (1957), but they may all be regarded as aspects, albeit subtle ones, of the three main mechanisms mentioned.

In their years - long quest to understand the cellular and genetic mechanisms that may trigger SUDEP, Noebels and his colleagues have studied the genes that are involved in the heart beat.

Messenger RNA (mRNA) serves as an important intermediary during gene expression, by relating the genetic information of DNA to the molecular mechanisms involved in manufacturing proteins.

The genetic findings are increasingly allowing us to understand the mechanisms involved, and to start to connect the genetic and environmental contributions,» says Mark McCarthy.

«Given the similarities in the molecules and the mechanisms involved in limb development in vertebrates and invertebrates, the fly is a very useful genetic model in which to identify new genes that potentially participate in limb development in vertebrates and their possible association with congenital diseases,» says Ana Ferreira, who has participated in the study.

Professor Peter Kraft at Harvard TH Chan School of Public Health, USA, says: «Given the size of these studies, we expected that we would find a lot of new breast cancer risk variants, but the studies tells us a lot more about which genes are involved, revealing many previously unsuspected genes and genetic mechanisms underlying breast carcinogenesis.

The molecular mechanisms involved in the development of cancer have been uncovered by extensive research over the past 30 years, culminating in The Cancer Genome Atlas, a National Institutes of Health project that identified and characterized many genetic mutations that fuel cancer.

This process has been seen before in other cancers, but this is the first time it has been shown to be involved in all pancreatic tumours, and that each tumour evolved different genetic mechanisms to do this.

The strategy of drug discovery may correct defects associated with genetic diseases as it continued to I - Stem is based on the access that pluripotent stem cells provide molecular mechanisms involved in these diseases.

«This impressive work demonstrates a new mechanism for how a relatively simple genetic network can respond to external cues and create the most optimal environment for viral replication,» said Gurol Suel, PhD, an associate professor of molecular biology at UCSD who was not involved in the study.

It could also provide better understanding of wound healing, which involves similar genetic mechanisms.

«It comes as no surprise to me that the members of ASHG have selected Dr. Nussbaum as their President - Elect,» said NHGRI Director Francis S. Collins, M.D., Ph.D. «Bob is a prominent leader in the field of human genetics and has made considerable contributions to identifying the genetic abnormalities and destructive mechanisms involved in Parkinson's disease and Lowe's Syndrome.

Moreover, PHENONIM - ICS is involved in European projects presenting a strong impact on human health: Interreg CARDIOGENE (Genetic mechanisms of cardiovascular diseases), GENCODYS (Genetic and epigenetic networks involved in cognitive dysfunctions), AgedBrainSYSBIO (Basic studies of brain aging), as well as projects in partnership with industry: MAGenTA (an Industrial Strategic Innovation project supported by Bpifrance about the treatment of major urogenital diseases) and CanPathPro (H2020 program), to develop a predictive modeling platform of signaling pathways involved in cancers.

Major themes of Dr. Drevets studies have involved: 1) characterizing the pathophysiology of mood disorders using multimodal neuroimaging technologies; 2) delineating neural circuits in which dysfunction is associated with major depressive episodes; 3) elucidating effects of genetic variants associated with the risk for mood disorders on neural function, structure and receptor pharmacology; 4) investigating the neural mechanisms of antidepressant and mood stabilizing treatments, and 5) developing novel therapeutics for mood disorders.

These resources comprise a «rice diversity research platform» that is widely used the international rice research community to understand the genetic basis of complex traits, to investigate molecular mechanisms involved in key forms of stress tolerance, and to efficiently utilize natural variation to breed highly productive rice varieties for the future that are more nutritious, resource - use efficient, and stress tolerant than those we currently grow.

Our primary experimental approach involves creation of engineered mouse strains with informative genetic mutations, characterizing these mice and their cells to elucidate molecular mechanisms underlying cancer phenotypes, and verifying these mechanisms in human cancer patient specimens.

Aging is a complex process involving various genetic, hormonal, and environmental mechanisms.

Researchers at Florida State University and the University of Missouri have pooled their information to further the investigation of the genetic causes of epilepsy in thirty breeds of dogs including poodles (all types,) The research into the genetic mechanism of the condition seems to point to a recessive gene, but there may be more than one gene involved and more research needs to be done.

If so, the mechanisms underlying this intergenerational transmission could be complex and may involve a heritable common genetic liability and environmental processes through postnatal relational variables.