Sentences with phrase «genetic mechanisms of»

The Rosalind Franklin Award committee also gives honorable mention to Rachel Dutton, PhD, of the University of California, San Diego, for her work on the genetic mechanisms of formation of microbial communities in cheese; and Elizabeth Murchison, PhD, of Cambridge University for her work on transmissible cancers in dogs and Tasmanian devils.

Identifying the genetic mechanisms of dental variation in cercopithecoid primates.

For example, the zebrafish, a common aquarium specimen, possesses the remarkable ability to rapidly replace damaged and lost body parts including limbs, heart, and nervous system, making it an ideal model for defining the genetic mechanisms of regeneration and healing and for identifying drug candidates for use in regenerative medicine.

The Institute «Clinique de la Souris» introduced in 2012 the project entitled «genetic mechanisms of the cardiovascular diseases» thanks to the effective cross-border partnership with the clinicians F.Spitz and W Maerz.

Moreover, PHENONIM - ICS is involved in European projects presenting a strong impact on human health: Interreg CARDIOGENE (Genetic mechanisms of cardiovascular diseases), GENCODYS (Genetic and epigenetic networks involved in cognitive dysfunctions), AgedBrainSYSBIO (Basic studies of brain aging), as well as projects in partnership with industry: MAGenTA (an Industrial Strategic Innovation project supported by Bpifrance about the treatment of major urogenital diseases) and CanPathPro (H2020 program), to develop a predictive modeling platform of signaling pathways involved in cancers.

Professor David Largaespada is the leader of the Genetic Mechanisms of Cancer Program in the University of Minnesota Cancer Center and holds the Margaret Harvey Schering Land Grant Chair in Cancer Genetics.

Her work on the genetic mechanisms of cardiomyopathies and muscular dystrophies has identified several genes that are important for cardiac and skeletal muscle membrane stability and produced insights into how heart failure and muscle dysfunction occur.

Their findings provide new insights into the genetic mechanisms of AI resistance, and may help pave the way to personalized cancer treatment in breast cancer.

Kronforst will lead the effort to analyze the molecular and genetic mechanisms of speciation in butterfly communities from temperate and tropical environments.

She is currently studying the cellular and genetic mechanisms of liver cancer with the hope of identifying new biomarkers and drug targets for this often fatal disease.

Geriomics: IFAR has one of the only scientific programs in the U.S. dedicated to studying the genetic mechanisms of diseases associated with old age.

The Genomics Facility also is working with other teams studying mutations in bladder cancer tumors; genetic mechanisms of sickle cell disease; viruses in Lake Michigan; and many other projects.

Darwin was able to establish natural selection, without any understanding of the genetic mechanisms of inheritance, or the source of novel variation in a population.

«Our analyses and simulations point towards a gradual evolution of taller teeth, and in our future studies we will explore whether tinkering with the genetic mechanisms of tooth formation in lab mice — which have short molar teeth — will replicate the evolution of taller teeth,» says co-senior author Ophir Klein, an associate professor at the University of California San Francisco School of Dentistry.

«Either on their own can't explain sex, but looking at them together we've shown that the Red Queen dynamics of co-evolving pathogens produces that changing environment that makes sex advantageous through the simple genetic mechanism of the Hill - Robertson theory.»

A gene can code for different proteins — with diverse functionality — through the genetic mechanism of alternative splicing (the cutting and rejoining of genes).

It was not until Gregor Mendel and the start of the 20th century that the genetic mechanism of inheritance began to be revealed.

David Grimes wrote a 672 page book about this subject just months ago: http://www.vitamin-d-deficiency.co.uk/ Magn is also required in each of the steps concerned with replication, transcription, and translation of genetic information, and thus it is also needed for the genetic mechanism of action of Vitamin D. To make things even more interesting, Ca / Magn - ratio seems to be one of the stronger single predictor of fatal heart attacks I can think of.

Gaining insight into the genetic mechanism of cancer, like the work by Dr. Bellone and Dr. Luff, will help with earlier diagnosis, better treatment and improved outcomes for animals impacted by cancer.

Researchers at Florida State University and the University of Missouri have pooled their information to further the investigation of the genetic causes of epilepsy in thirty breeds of dogs including poodles (all types,) The research into the genetic mechanism of the condition seems to point to a recessive gene, but there may be more than one gene involved and more research needs to be done.

Not exact matches

MIN - 102 has a unique mechanism of action for X-ALD, a genetic disease characterized by progressive neurologic deterioration with no available pharmacological treatment.

Minoryx harnesses its unique mechanism of action for potential use in X-ALD, a genetic disease characterized by progressive neurologic deterioration with no available pharmacological treatment.

The theory of evolution not only says that life evolved, it also includes mechanisms, like mutations, natural selection, and genetic drift, which go a long way towards explaining how life evolved.

To make sense of the genetic data, one disbelieving in macro evolution would have to provide a much more convoluted and absurd mechanism.

@Bill Deacon,»... evolutionary biology can not provide a positive causation for the digital encoding of these strands...» I'm not certain why you use the loaded language or «digital encoding», but evolution does provide a mechanism for changes in the genetic makeup of all organisms.

«The forms of a living being are not but rather come to be,» says Ludwig von Bertalanffy (BW 120), and his «organismic» biology and later general system - theory for overcoming the opposition between mechanism and vitalism has given central insights of Whitehead a new formulation on the basis of science, 8 Something similar holds for all the directions of research which Jean Piaget has brought to the [264] concept of genetic structuralism.9 The genetic epistemology founded by Piaget has proved through empirical research on the problem of knowledge the fruitfulness both of genetic analysis and of Whitehead's principle of process.

The characteristics studied by Darwin implied the evolutionary process; the fossils record demonstrated how many species evolved and added weight to the argument that all species evolved according to the same mechanism of evolution; the genetic data PROVES that the implication of the characteristics and the evidence of the fossil record was interpreted CORRECTLY..

There are of course many mechanisms that are involved in these concepts, such for example as genetic assimilation established by Waddington (1957), but they may all be regarded as aspects, albeit subtle ones, of the three main mechanisms mentioned.

if you are, see: berkely.edu: Evolution 101: Mutation Is Not «Directed» The mechanisms of evolution — like natural selection and genetic drift — work with the random variation generated by mutation.

To quote the researchers: «Thus, modification of this PIP2 regulatory domain by genetic, biochemical, or pharmacological mechanisms may have profound effects on sensitivity of primary afferent nerve fibers to chemical and thermal stimuli under normal or pathological conditions.»

A group of biologists from the Missouri - based Donald Danforth Plant Science Center have uncovered a genetic mechanism that could increase the yields of some of the world's most important cereal crops, like maize and sorghum.

Blood pressure responses to high and low salt intakes may share similar genetic control mechanisms, according to a new study published in the Journal of Human Hypertension.

While the current understanding of reproduction and genetics does not yet call for a complete study of a potential gestational carrier's genetic profile (and certainly the current state of understanding does not offer us any kind of screening mechanism that would be helpful, anyway), intended parents deserve to know the various influences that could impact their baby's health.

Post-partum depression poses substantial adverse consequences for mothers and their infants via multiple direct biological (i.e., medication exposure, maternal genetic factors) and environmental (i.e., life with a depressed mother) mechanisms.8, 9 From the earliest newborn period, infants are very sensitive to the emotional states of their mothers and other caregivers.10, 11 Maternal mood and behaviour appear to compromise infant social, emotional and cognitive functioning.11 - 15 As children grow, the impact of maternal mental illness appears as cognitive compromise, insecure attachment and behavioural difficulties during the preschool and school periods.6,16 - 19

When looking into mechanisms that might affect the levels of SMN protein in neurons, the researchers scanned a genomic database called the UCSC Genome Browser and identified two genetic sequences that matched the opposite DNA strand of the SMN gene.

Genetic drift was embraced as an additional mechanism of evolutionary development in the modern synthesis of the theory.

Understanding the mechanisms that expand protein functional diversity is important for understanding the phenotypic diversification of organisms and their genetic systems.

The study, which combined genetic analysis with a 19 - year - long selection experiment, supports the idea that the mechanisms of adaptive evolution may be more predictable than previously suspected.

Seeking one mechanism to explain the induction of cancer by many different agents, Huebner and Todaro had suggested that retrovirus oncogenes are a part of the genetic baggage of all cells, perhaps acquired through viral infection early in evolution.

Messenger RNA (mRNA) serves as an important intermediary during gene expression, by relating the genetic information of DNA to the molecular mechanisms involved in manufacturing proteins.

«Given this mechanism, ataluren offers the potential for a new therapeutic approach for multiple nonsense mutation genetic disorders by targeting the underlying cause of the disease.»

As a graduate student working on the mechanisms of photosynthetic enzymes, my Ph.D. advisor and I pondered how to increase plant productivity through genetic engineering.

This work confirmed these suspicions and discovered novel molecular genetic mechanisms driving the evolution of HPV - inactive cancers.

This study highlights the shared genetic etiology of many canine and human genetic disorders, and provides new tools to investigate PRA mechanisms while the beloved dogs benefit from genetic testing.

«It could be one of the mechanisms for genetic inheritance of disease — a route we haven't thought of before,» says Spector.

The pair «discovered a fundamental mechanism for controlling the flow of genetic information», the Nobel prize jury said.

Ma said this type of mutation appears to be unique to soybeans as semideterminancy in other plants such as tomatoes and chickpeas is caused by a different genetic mechanism.

Researchers at the University of Zurich have now identified a mechanism how cells pass on the regulation of genetic information through epigenetic modifications.

In order to describe the mechanism of a membrane sensor which measures the degree of lipid saturation in the yeast cell, the researchers used genetic and biochemical methods and simulated the motions and underlying forces of membrane lipids over a period of a few milliseconds by means of extensive molecular dynamic simulations.

The team still doesn't understand the genetic mechanism responsible for the effect, but study author and evolutionary biologist Francisco Rodríguez - Trelles of the Universitat Autònoma de Barcelona notes a clue: Flies carrying the «summer» inversions to deal with the heat wave produced five times more offspring than they would have in ordinary years.