Sentences with phrase «genetic obesity risk»
«Saturated fat intake may influence a person's expression of genetic obesity risk.»
https://www.sciencedaily.com/ Not exact matches
The Mayo Clinic states common risk factors as changes in female hormones, older age, obesity, and inherited genetic conditions — not sugar or beverage consumption.
Results were similar in analyses of sleep patterns; among participants with some genetic risk of obesity, those who woke up frequently or slept more restlessly had higher BMIs than those who slept more efficiently.
«Physical inactivity and restless sleep exacerbate genetic risk of obesity: Findings reported at ASHG 2017 Annual Meeting.»
Low levels of physical activity and inefficient sleep patterns intensify the effects of genetic risk factors for obesity, according to results of a large - scale study presented at the American Society of Human Genetics (ASHG) 2017 Annual Meeting in Orlando, Fla..
«We wanted to find out if obesity - related genes and activity level have an interactive effect on obesity risk — if there is a «double whammy» effect of being both at genetic risk and physically inactive, beyond the additive effect of these factors,» said Dr. Wood.
The researchers computed a genetic risk score for each participant based on 76 common variants known to be associated with elevated risk of obesity, and analyzed this score in the context of accelerometer data and participants» BMIs.
Genetic risk score could be useful in identifying people who are predisposed to obesity and could ultimately lead to personalized dietary recommendations.
Genetic risk factors may make some individuals more susceptible to these changes in the environment, and thus more prone to obesity.
Although several environmental and genetic factors have been shown to contribute to the risk of T2D (e.g., obesity, inactivity, and aging), the origin of this disease is still not completely understood (Stumvoll et al., 2005).
Check out Diane's other recent publication «Genetic risk for obesity predicts nucleus accumbens size and responsivity to real - world food cues»
This genetic risk factor is independent of other risk factors, such as cholesterol, obesity and smoking, and therefore provides an additional method for identifying individuals who may derive benefit from earlier and more aggressive prevention efforts.
Angela C Estampador, 1,2 Paul W Franks1, 3,4 1Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden; 2Department of Endocrinology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; 3Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden; 4Department of Nutrition, Harvard School of Public Health, Boston, MA, USA Abstract: Evidence has emerged across the past few decades that the lifetime risk of developing morbidities like type 2 diabetes, obesity, and cardiovascular disease may be influenced by exposures that occur in utero and in childhood.
The genes were identified through population - and genome - wide linkage scans and association analyses of at - risk haplotypes utilizing genetic and clinical data from the 17,000 participants in deCODE's obesity program in Iceland.
ASHG 2017: Physical Inactivity and Restless Sleep Exacerbate Genetic Risk of Obesity ASHG Press Release — October 20, 2017
And, we'll tie together the previous levels by connecting how inflammation related to the previous system discussions - poor digestion, immune dysfunction, hormonal dysregulation, genetic snps, and environmental toxin exposures (including emotional toxins)- contribute to an increased risk of chronic rehab challenges, including chronic joint pain, poor surgical or injury recovery, obesity, memory loss or dementia, diabetes, or even poor sports performance.
The researchers measured the participants» genetic risk by identifying how many of the 32 known variants of the so - called obesity gene each person had.
Regarding the child, the importance of the intrauterine and early postnatal environments for metabolic programming and modifications of the epigenome is increasingly recognised, 12 — 14 particularly for metabolic diseases such as obesity and diabetes.15 Thus, GDM is related to macrosomia at birth (> 4 kg), to excess body fat and (central) obesity and to insulin secretion in infants and children, the obesity being in part mediated by maternal body mass index (BMI) or birth weight.16 — 23 Intrauterine exposure to GDM also doubles the risk for subsequent type 2 diabetes in offspring compared with offspring of mothers with a high genetic predisposition for type 2 diabetes, but with normal glucose tolerance during the index pregnancy.24 Maternal prepregnancy overweight and excessive gestational weight gain also predict high birth weight and adiposity during infancy.12 25 This is highly relevant, as up to 60 % — 70 % of women with GDM are overweight or obese before pregnancy.26 Finally, maternal lifestyle behaviour such as a high fat diet or lack of physical activity during pregnancy can influence offspring adiposity independent of maternal obesity.12 27
A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder.
We are exploring new insights into the genetic roots of autism; finding pediatric bio-behavioral markers of bipolar disorder; creating effective therapies for OCD; devising effective prevention strategies for adolescent sexual risk behaviors and obesity; and much more.