Sentences with phrase «genetic pathways»

This nutrient is responsible for hundreds of different genetic pathways in the body.

Further, it will be important to isolate specific genetic pathways shared with both substance involvement and psychiatric illness.

Similar techniques could be used to activate virtually any gene or genetic pathway without the risk of introducing potentially harmful mutations.

Godwin's findings are a validation of the MDI Biological Laboratory's unique research approach, which is focused on studying regeneration in a diverse range of animal models with the goal of gaining insight into how to trigger dormant genetic pathways for regeneration in humans.

Additionally, the compounds called polyphenols found in blueberries trigger the specific genetic pathways which combat the inflammation caused by the COX - 2 enzyme.

There is however room for optimism as amlexanox has been found to be safe for patients, and humans also have the same genetic pathways as mice.

In a paper recently published in the journal Aging Cell, MDI Biological Laboratory scientist Aric Rogers, Ph.D., sheds light on an important genetic pathway underlying this process, raising the possibility that therapies can be developed that can...

The study is the first to implicate a single genetic pathway in the development of both the forebrain and the face, and it may provide insights into some birth defects.

Research led by investigators in veterinary and human medicine has identified genetic pathways that exacerbate severity of canine compulsive disorder in Doberman pinschers, a discovery that could lead to better therapies for obsessive compulsive disorder in people.

Second, curcumin helps stimulate a very important genetic pathway known as the NRF2 pathway, which activates a whole set of antioxidant genes, including genes like glutathione synthase (which is the body's natural way of making glutathione) and glutathione peroxidase (which is the way the body uses glutathione to fight off damage) and is just one way that curcumin fights damaging oxidants.

Using this model, which has increased levels of a key developmental protein called NOTCH, they discovered a new genetic pathway involved in the development of this portions of the brain.

In a new study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic, cells in Caenorhabditis elegans, a one - millimeter nematode commonly used as a model for aging studies in labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cells.

Because vitamin D is responsible for so many genetic pathways in the human body, deficiencies are linked to chronic disease while optimal levels are linked to an actual preservation of telomeres.

«We hope eventually to use the system to look at how genetic pathways change in response to NIHL.

The revolution in our understanding of the biological processes that influence aging really started with the small roundworm, C. elegans, in the late eighties and early nineties and this organism continues to teach us about how evolutionarily preserved genetic pathways influence health and longevity.

Linking the vascular endothelial growth factor (VEGF) genetic pathway with a specific disease characteristic among SLE patients represents an important step towards unravelling the genetic basis of different SLE clinical presentations.

The fluctuating proteins synthesized by clock genes control additional genetic pathways that connect the molecular clock to timed changes in an animal's physiology and behavior.

In her latest work, Murphy wanted to know whether reproduction and life span were two aspects of the same overall genetic pathway or completely separate entities.

«It completely turns upside - down what was thought to be a fundamental aspect of cell cycle progression in all cancer cells driven by one of the most common genetic pathways mutated in cancer, namely the p16 - cyclin D pathway.»

«New tumor analysis method identifies high - risk prostate cancer: Cancer cells» genetic pathways show which patients are likely to develop aggressive types of the disease.»

In this replication stage, the significant association between mouth ulcers and the VEGF genetic pathway was confirmed.

A total of 11 clinically relevant SLE phenotypes were tested for association with over 700 reference genetic pathways.

The volunteers had no significant problems tolerating the extract and the lining of their mouths showed that the same protective genetic pathway activated in the laboratory cell tests was activated in their mouths, meaning that the sulforaphane was absorbed and directed to at - risk tissue.

In doing so, they discovered that a fundamental genetic pathway (WNT / β - Catenin) plays an essential role in directing development of the corpus / fundus region of the stomach in mouse embryos.

In the first clinical proof of its kind, a drug has dramatically shrunk cancerous tumors by disrupting a key genetic pathway.

Therefore, although we have some understanding of the major genetic pathways that influence aging through single genes, we're really only scratching the surface of how small variations in many genes simultaneously could add to or detract from how quickly we age.

Doctors are already using drugs, such as Herceptin, that specifically target malfunctioning genetic pathways in tumors, but no such therapies are currently available for certain aggressive forms of the disease, such as the triple negative subtype.

The researchers involved in the landmark study, which was published Wednesday in the journal Nature, say the discovery of this new genetic pathway probably reveals what goes wrong neurologically in a young person diagnosed with the devastating disorder.

The embryonic Drosophila central nervous system similar to the human spinal cord is a paradigm for understanding the cellular processes and genetic pathways regulating the formation and maintenance of a diverse population of nerve cells.

La Jolla, CA — Scientists at the Salk Institute have discovered a novel genetic pathway that ensures body organs develop correctly and in the right position during embryonic development.

«This work provides the first evidence for genetic adaptation in diving human populations and elucidates genetic pathways important in hypoxia tolerance,» Tatum Simonson, who studies the physiology and genetics of high - altitude adaptation at the University of California, San Diego Health Sciences, and was not involved in the work, writes in an email to The Scientist.

For example, the SCN detects light at dawn and through a complex cellular genetic pathway, turns off the melatonin that keeps us asleep, and turns on cortisol to wake us up.

For example, by deep sequencing bacterial DNAs from diseased and healthy subjects, the inventors propose that features associated with certain microbiome compositional and / or functional features (e.g., the amount of certain bacteria and / or bacterial sequences corresponding to certain genetic pathways) can be used to predict the presence or absence of an autoimmune condition.

When structures in different species are thought to result from common, inherited genetic pathways, those structures are termed homologous.

What has become clear from their research is that there is no single genetic pathway to controlling HIV; there likely are multiple routes, each with their own combination of genetic and environmental factors.

The Haematological Cancer Genetics team, led by George Vassiliou, studies the genes and genetic pathways involved in the development of blood cancers, with a particular emphasis on Acute Myeloid Leukaemia and related malignancies.

Although it may seem unlikely that the 959 - celled roundworms have much in common with humans, many genetic pathways were conserved during the course of evolution.

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2016) showed for the first time an association between a specific genetic pathway and the development of mouth ulcers in patients with Systemic Lupus Erythematosus (SLE).

But such studies can not identify a causal link between these genes and the disease, and often miss genes that affect a larger number of genetic pathways, which may have a large impact on the disease process.

In a paper published in this week's early online edition of Nature, they report the discovery of a new genetic pathway in plants, made up of four genes from three different gene families that control the density of breathing pores — or «stomata» — in plant leaves in response to elevated CO2 levels.

David Kessler, the former commissioner of the Food and Drug Administration, is calling for a big government - funded research project to help fill in the gaps in genetic pathways in people, which are turning out to be far more complex than expected for illnesses such as heart disease and which may be beyond the ability of private companies and smaller labs to figure out and pay for.

«These newly identified genes and genetic pathways in primary melanoma could give researchers new targets for developing personalized treatments for melanoma, and potentially other cancers,» said Stacie Loftus, Ph.D., lead author and staff scientist in the Genetic Disease Research Branch at the National Human Genome Research Institute, a part of NIH.

«By targeting a genetic pathway in cells that ordinarily restrain the immune response to cancer, we may be able to convert them into cancer fighters.

Participants who lacked two genes involved in a genetic pathway that helps the antioxidant glutathione remove carcinogens and toxicants from the body saw an even bigger benefit to taking the watercress extract, which increased their detoxification of benzene by 95.4 percent, acrolein by 32.7 percent and crotonaldehyde by 29.8 percent.