Sentences with phrase «genetic regions»
This brings the total number of genetic regions associated with the disease to 16.
sciencedaily.com
Recent studies of the human genome have identified genetic regions associated with autoimmune diseases such as type 1 diabetes.
Among them were sharp differences between the three groups in genetic regions involved in smell and taste — suggesting that each population's senses had adapted to the new smells and foods they encountered.
They found several genetic regions that were shared by the affected individuals.
In addition to the nine genetic regions newly associated, they also saw strong signals at three regions of the genome previously associated with the disease.
A genetic analysis showed that the more aggressive bees tended to share five specific genetic regions, one of which originated with African bees.
Other genetic regions were also found to differ between cases and controls.
As a result, they didn't know whether traits were governed by a large number of genetic regions, each contributing a small effect, or by a few regions with large effects.
21 Sept 2012: Jimmy Liu disscusses his recent research discovering and refining genetic regions linked to susceptibility for primary biliary cirrhosis, or PBC, an immune - mediated disease that causes the progressive destruction of liver bile ducts.
Through this work they have discovered the origins of the dog in Central Asia, and also identified genetic regions involved in domestication and local adaptation (did you know Himalayan dogs have a gene for high altitude adaptation?).
The studies identified genetic regions specifically associated with either oestrogen - receptor positive or oestrogen receptor negative breast cancer, underscoring the fact that these are biologically distinct cancers that develop differently.
«Study of complex genetic region finds hidden role of NCF1 in multiple autoimmune diseases.»
We hope that with more samples from patients, we'll be able to link more genetic regions to the disease, and it will become easier to identify underlying pathways that could act as therapeutic targets.»
But until now, no one had undertaken a genome - wide scan to look for genetic regions that confer exceptional life - span in humans.
Co-author Heidi Parker, a geneticist at NHGRI, says that because humans initially bred dogs for specific traits — say, smaller body size or calm temperament — selection created a population «bottleneck» that narrowed the genetic variation in offspring, leaving them with just a few specific clusters of variable genetic regions.
Hanna applied new sequencing strategies to read millions of short genetic regions and used powerful computers and assembly software to compile the genome again.
«Given the biologic relevance of mercury and selenium for human health and prior candidate gene studies demonstrating heritability, we anticipate discovery of major novel genetic regions that will greatly advance our understanding of the intersection between genes, dietary habits, and metabolism,» the research team told Harvard Public Health Now, a publication of the Harvard School of Public Health.
A study last year strongly implicated 108 genetic regions as culprits in schizophrenia.
The structure shows that the genome is arranged such that the most active genetic regions are on the interior and separated in space from the less active regions that associate with the nuclear lamina.
[PSI +] removes the stop sign that normally appears when proteins are being synthesized: Ribosomes roll through their normal stopping point on an RNA strand and read into fresh genetic regions.
New research taking people's life histories into account finds new genetic regions that may increase the risk of major depression
Previous studies have indicated that these remarkable differences between male morphs are under strict genetic control and are determined by a single genetic region.
Previous work had implicated several genetic regions, including one on the X chromosome called Odysseus, which is expressed in the testis.
A genomic study of baldness identified more than 200 genetic regions involved in this common but potentially embarrassing condition.
A study led by Åsa Johansson (Uppsala University / SciLifeLab) uncovers that tea consumption in women leads to DNA methylation of genetic regions associated with cancer and estrogen metabolism.
They pinpointed 287 genetic regions linked to the condition.
Dr. Seshadri, founding director of the Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases at UT Health San Antonio and holder of the university's Robert Barker Distinguished University Chair, said the identification of genetic regions that are strongly correlated to stroke will increase potential targets for stroke drug development.
When scientists in Israel tested BRCA1 carriers from the dispersed Jewish populations, they discovered that all shared the same basic spelling in the genetic region of 185delAG.
Such stretches of DNA point to genetic regions that are critical to a species» survival and development, as these regions are the product of «selective sweeps» in which all or most organisms in a geographic location come to depend on a certain genetic trait.
It found that genes associated with depression are involved in brain cell development, and that there was overlap between these genetic regions and those linked to schizophrenia and other mental illnesses.
«More than one genetic region is associated with susceptibility to sarcoids, and they don't completely determine whether or not a horse will develop the disease once it's exposed to BPV.»
Three of the genetic regions associated with PSC fall within a single biological system that underlies variation in T cells, cells important to our immune response.
Researchers have newly associated nine genetic regions with a rare autoimmune disease of the liver known as primary sclerosing cholangitis (PSC).
Of these twelve genetic regions, six are also associated with IBD, while the six other regions showed little to no association in a recent large study of IBD.
In an extended analysis, the team identified an additional 33 genetic regions that are also involved in several common immune - mediated conditions (celiac disease, Crohn's disease, ulcerative colitis, type 1 diabetes, rheumatoid arthritis, sarcoidosis and psoriasis).
The team showed that only half of the newly associated genetic regions were shared with inflammatory bowel disease (IBD).
When the researchers looked at the pattern of these genetic regions, they discovered that this differed from that of those regions involved in predisposition to other common diseases.
This value indicates the percentage of these genetic regions identical to those of the 1968 pandemic strain and helps determine how well an influenza virus can evade a host's immune response.
Nestadt says the genome - wide association study findings of a PTRPD - OCD link add to evidence that the genetic region they identified is important.
Several of the genetic regions contributing to face shape detected by the researchers contain genes known to play a role in facial development and facial abnormalities.
By also examining this genetic region in two other families with similar disorders, the researchers were able to pinpoint a mutation in a specific gene, NT5E, which is involved in breaking down calcification in the arteries.
These results help clarify the factors that drove strain extinction in the CC, reveal the genetic regions associated with poor fertility in the CC, and serve as a resource to further study mammalian infertility.
March 26, 2008 Journal of the American Medical Association: Two identical copies of genetic regions may predispose to common cancers We have long known that variety is a «good thing» or as the ancient adage goes, «Variety is the spice of life.»
Researchers have newly identified three genetic regions associated with primary biliary cirrhosis (PBC), the most common autoimmune liver disease, increasing...
A common variant of the p16 (INK4a) genetic region is associated with physical function in older people.
Next, the researchers created NOD mice that were modified with CRISPR / Cas9 genome editing tools to remove one genetic region that is needed to produce pTregs.