Sentences with phrase «genetic sequencing effort»

A massive genetic sequencing effort on seed - bank holdings to document what exists in the collections, to strategically target experiments to evaluate what traits a plant has (called phenotyping) and to begin to predict plant performance.

Not exact matches

Venter, who is one of the first people to sequence the human genome, co-founded the company in effort to discover early genetic markers for a variety of disorders.

But rather than buying up a genetic research outfit, it decided to build its own in the form of the Regeneron Genetics Center (RGC), an ambitious four - year old effort to sequence as many exomes (the protein - encoding part of the genome) as possible, pair them with medical records, and accelerate drug development.

«Intensive DNA sequencing efforts to find the genetic «drivers» of metastasis, which is what kills patients in up to 80 percent of cases, have thus far been disappointing, to say the least,» he said.

The 15 AACR scientists, who were already in Washington, D.C., to meet with the U.S. Food and Drug Administration on genetic testing for cancer patients, tossed around ideas including expanding NCI's tumor genome - sequencing efforts and getting the government to cover the costs of genomic tumor profiling.

They enable molecular biologists and geneticists to selectively chop DNA into pieces, which can then be assembled into new versions of the gene, inserted into the genomes of other organisms, or sequenced as part of an effort to map an organism's genetic material.

«In addition to funding rice sequencing, the [Thai] government is about to launch an effort that will move on to functional genomics,» says Apichart Vanavichit, a molecular biologist at Thailand's National Center for Genetic Engineering and Biotechnology in Nakorn Pathom, which is helping to sequence chromosome 9.

To demonstrate the utility of the gorilla Y chromosome sequence they generated, the researchers designed genetic markers that can be used to differentiate the genetic relatedness among male gorillas and thus to aid in conservation genetics efforts targeted at preserving this endangered species.

The barley genome sequence also enabled the identification of regions of the genome that have been vulnerable to genetic bottlenecking during domestication, knowledge that helps to guide breeders to optimize genetic diversity in their crop improvement efforts.

Their DNA was the basis of the first effort to compile a complete Neandertal genetic sequence, which was published in 2010.

In this research effort, scientists conducted DNA sequencing on more than 500 adults and children with DCM and more than 1,100 healthy controls from several ethnically distinct cohorts to learn about the genetic profile of the disease.

«Usually that would require extensive genetic analysis with complex sequencing methods, but our methodology achieves that goal quickly and with minimal experimental effort.»

By better understanding the limitations of genome - wide sequencing, Vogelstein notes, researchers and policymakers might be better able to direct funding and efforts to areas, such as Alzheimer's disease, where a person's genetic profile might have a very real effect on their likelihood of getting the disease.

The convergence of several factors explains the trend: cheaper genetic sequencing technologies, the discovery of new oncogenes (genes that can cause a normal cell to become cancerous), a new generation of computers and bioinformatics that can analyze vast amounts of data, and a multibillion - dollar effort by researchers inside and outside the pharma industry to develop targeted drugs and companion diagnostics for cancer.

Fifteen teams analyzed nearly 500 patients» tumors for genetic aberrations and sequenced the protein - coding DNA of 316 samples — by far the largest cancer sequencing effort to date.

Much of the work to isolate the PHS gene came from Gill and his colleagues» efforts to fully sequence the genome — think genetic blueprint — of common wheat.

After all, the Human Genome Project, a massive effort of the National Institutes of Health and U.S. Department of Energy to map our complete genetic sequence, took just 13 years — 1990 to 2003.

Sparked from the efforts of the T2D - GENES Consortium (Type 2 Diabetes Genetic Exploration by Next - generation sequencing in multi-Ethnic Samples; T2D - GENES) to aggregate and share results from large - scale T2D sequence and genotype datasets, the prototype T2D KP was built with seed funding from the NIDDK via the T2D - GENES Consortium and the Slim Initiative for Genomic Medicine in the Americas for T2D (SIGMA T2D).

Genetic variability revealed in malaria genomes newly sequenced by two multi-national research teams points to new challenges in efforts to...

In the new study, the lab has conducted the first large - scale whole genome sequencing study of asthma drug response in African Americans and Latino children in an effort to pin down the genetic factors contributing to reduced albuterol response more precisely than possible in previous association studies.

Paul Lasko and Beat Suter, at McGill University, are extending the work of the Wright laboratory (Stathakis et al., 1995) in the genetic and molecular analysis of a similarly sized genomic segment comprising polytene regions 37 and 38 and this will be an early target for the BDGP sequencing efforts.

As highlighted in the final print issue of Genome Technology, investigators leading clinical sequencing efforts have faced ethical dilemmas already, such as the return of genetic information to family members in the event that a patient dies.

Most of that is by design: the 1,000 Genomes Project generated and made available sequence data for more than 1,000 individuals in an effort to further characterize human genetic variation.

Here, we combined the efforts of population geneticists and genetic genealogists to use the potential of full Y - chromosome sequencing for reconstructing haplogroup Q3 phylogeography and suggest possible linkages to events in population history.

This unique structure of dog breeds has been useful in determining the genetic basis for many desirable and deleterious traits, an effort facilitated by new genetic technologies emanating from the sequencing of the canine genome [24].