Sentences with phrase «genetic studies such»

It is important to recognize the power constraints of quantitative genetic studies such as those using twin comparisons.

Genetic studies such as this one may help anthropologists understand those migrations — and their timing — even better by giving them a genetic «clock» to use when studying today's humans, or potentially DNA extracted from ancient bones.

This theory has been debunked by recent genetic studies such as Legacy: A Genetic History of the Jewish People.

Not exact matches

Phase I funding — which allows up to $ 250,000 for an academic idea, such as decoding the genetic sequence of a protein or studying targeted drug delivery by using magnetic nanoparticles — is available from federal funding and foundations.

«[A.I.] can help analyze large data sets from sources such as clinical trials, health records, genetic profiles, and preclinical studies; within this data, it can recognize patterns and trends and develop hypotheses at a much faster rate than researchers alone,» says Deloitte.

A degree of kinship between human beings and the rest of physical creation has always been clear to an extent, but the depth and detail of our interrelationship with the rest of life on the planet is being confirmed over and over again in breathtaking detail by new scientific advances such as genetic studies and molecular biology.

biochemical evidence such as Cytochrome - cyto - C is just one of the thousands of sequences and is not proof of common ancestry, as there are more variations than similarities in the genetic code, on the other hand a study of the amino acid make - up reveals that man is closer to lamprey than are fish.

Such studies show that we are all walking genetic junkyards: Recent U.S. research suggests that every individual carries, on average, 313 disease - causing mutations.

Because there is a clear genetic predisposition to IBD, these populations should probably be composed of families that include persons who already have IBD [such as the studies conducted by Koletzko et al (20, 26)-RSB-.

Baylin and Johns Hopkins scientist Michelle Vaz, Ph.D., first author on the study, suspected that the interplay of epigenetic and genetic changes may occur when normal lung cells develop into cancer, but, Baylin says, the timing of such changes was unknown.

Of the thousands of ancestral variants reintroduced into modern humans, only 41 have been linked in genetic studies to diseases, such as skin conditions and neurological and psychiatric disorders, he said.

Cancer cells which arise due to genetic mutations are just such cells, and there are studies which suggest that microchimeric cells may stimulate the immune system to stem the growth of tumors.

Whilst there I worked on a research project studying the genetics of inherited deafness and also performed routine genetic screening and prenatal diagnoses for diseases such as Duchenne muscular dystrophy and cystic fibrosis.

Called gain - of - function experiments, the studies aim to understand genetic changes that can make viruses such as bird flu, SARS (severe acute respiratory syndrome), and MERS (Middle East respiratory syndrome) more transmissible from person to person.

According to Dr. Philip Awadalla, senior author and principal investigator, «the fact that two very close populations (French versus French Canadians) accumulate such an excess of differences in rare variants has important consequences in the design of genetic studies, including the identification of possibly damaging mutations associated with diseases specific to this population.»

The study, led by scientists from the University of Chicago, uses a novel method to measure genetic predisposition for telomere length, rather than physiological measures which are confounded by factors such as age and lifestyle.

Results of each statistical test should be reported in full with the value of the test statistic and p - value, and not simply reported as significant or non-significant; more than two significant digits on p - values are usually not needed except in situations of extreme multiple testing such as in genetic association studies where stringent corrections for multiple testing might be used.

«Isn't it plausible that many or most of the cancers attributed to replication errors in this study involve genetic or environmental factors that are too ubiquitous to be identified as such?»

The research team's hunt for such age - related genetic associations involved studying more than 8 million single nucleotide polymorphisms — changes of one nucleotide for another at a particular spot in the DNA — in 2,693 individuals.

In addition to helping farmers check crop health, the new system will be helpful for studying how plants respond to changes in growing conditions and for high - throughput phenotyping, an automated method used in crop research and development to analyze how genetic modifications affect plant characteristics such as leaf size or drought resistance in a large number of plants.

Neither threats of nor actual discrimination based on genetic information should be allowed to impede access to therapies based on the discoveries of such genetic research or the ability and willingness of persons to participate in critical studies.

«This study extends the narrative that many of the effects of disease - related genetic variation are specific to a certain context, such as a given immune cell type,» said Barbara Stranger, PhD, University of Chicago, senior study author.

Prof. Schuelke emphasizes: «Our results are a good example of how the study of rare genetic diseases can provide insights into general disease mechanisms, which may also play a role in other conditions, such as paraplegia, and which may give rise to the development of regenerative therapies.»

Segal doesn't try to explain such spookily synchronized outcomes, but her studies suggest that the harmony between identical twins stems in large part from shared genetic identity.

The discovery could shed light on why many human genetic studies have previously not been able to fully explain how certain diseases, such as type 2 diabetes and obesity, are inherited.

Lead researcher Professor Vardhman Rakyan from QMUL said: «The fact that genetic variation of ribosomal DNA seems to play such a major role suggests that many human genetics studies could be missing a key part of the puzzle.

Although prior twin studies had hinted that nonheritable factors contribute to some autoimmune disorders, such as multiple sclerosis, the recent analysis was one of the first to quantify genetic and environmental effects on the general immune system.

As far as we're aware, it's the first study worldwide to show this in such detail, including a large number of genetic variants.»

And large, genome - wide studies searching for genetic underpinnings for more common diseases, such as lung cancer or autism, have pointed to the nether regions of the genome between the protein - producing genes — areas that were often thought to contain «junk» DNA that was not part of the pantheon of known genes.

This allows us to study the effects of specific substances or other sleep - influencing factors such as age and genetic disposition.»

Now, in a series of recent studies, scientists at the University of Missouri are using whole genome sequencing through the 99 Lives Cat Genome Sequencing Consortium to identify genetic variants that cause rare diseases, such as progressive retinal atrophy and Niemann - Pick type 1, a fatal disorder in domestic cats.

Thus, this study might provide a clue how these diseases might be linked on the genetic level which is interesting as such.

Phylodynamics is the study of genetic variations in pathogens, and the effect of such variations on their transmissions.

Epigenetic translates to «above genetic» and is an emerging field of study that looks at how environmental factors — such as infections, pollutants, stress and, in this case, long - term exposure to drugs that block estrogen synthesis — could influence a person's DNA.

A study published in May found that this duplication (or absence) of genetic material relates to a distinctly different brain structure, such as a larger or smaller corpus callosum, the tract of white matter connecting the brain's hemispheres.

The study indicates that brain networks supporting basic psychological functions such as attention do not communicate appropriately in young individuals at genetic risk for illnesses such as schizophrenia or bipolar disorder.

The results — from studies of crows, butterflies, mosquitoes, fish and other organisms — suggest that the concept of species is even more muddled than we thought, and that genetic changes don't always align with more visible ones, such as appearance.

But the subjects are few, he notes, and such studies are always complicated by genetic differences between the subjects.

Such a large pool of patient data would greatly facilitate research on ALTS and open new avenues of study into genetic aspects of other forms of laryngotracheal stenosis.

The study raises interesting questions about why the two separate invasions show such similar genetic patterns.

Researchers will have to conduct rigorous computational and genetic studies to identify such a compound.

Said Flask, «In this initial paper, we validated our new methodology, opening the possibility for numerous follow - on application studies in cancer, genetic diseases such as cystic fibrosis, and metabolic diseases such as diabetes.»

Many of the characteristics that make up a person's face, such as nose size and face width, stem from specific genetic variations, reports John Shaffer of the University of Pittsburgh in Pennsylvania, and colleagues, in a study published on Aug. 25 in PLOS Genetics.

The three stages of CD8 + T cell development are well known, but the current study identifies a detailed map of the regulatory circuitry, such as interactions between enhancers and promoters — genetic regulatory regions that function together in driving genes to transcribe proteins to carry out biological processes.

They have generated excitement over the past few decades because scientists can study them in the laboratory to discover the genetic switches that control the development of specialized tissues in the embryo and fetus, and also because of their potential to replace body tissues that have broken down, such as pancreatic cells in those with diabetes or heart muscle cells in those with congestive heart failure.

Such rare individuals could shed light on «what happens when parts of the genetic material are not working,» says study co-leader Richard Trembath.

The researchers wrote that further studies would be needed to assess whether dopamine - like drugs can reduce food cravings and addiction, and whether such drugs could reduce body fat in Asians with the genetic variation.

Such families can be studied by modern molecular genetic methods in ways that allow the causative gene to be identified.

Animal studies have also found that a stress to a parent, such as exposing a pregnant mouse to toxic chemicals or mildly shocking a mouse father to make it fear an odor, can result in effects such as infertility or changes in behavior that persist for two generations or more yet can't be explained by genetic mutations.

In addition, as public concern with genetic technologies such as CRISPR / Cas9 is currently a social issue in Japan, studies using this popular and widely - grown plant may help to educate the public on this topic.