Genetic studies using samples along the distribution range of both subspecies and based on a few dozen nuclear markers have revealed loci of relatively high divergence (0.3 — 1.2 %) between subspecies embedded in a genome otherwise characterized by low levels of differentiation and high levels of bidirectional gene flow [21], [24]--[26], likely facilitated by high effective population sizes, high dispersal, and a relatively short generation time [21], [24]--[26].
Evaluation of root rot symptoms for
her genetic study uses chestnuts grown and tested in containers developed by Steve Jeffers, professor of plant pathology at Clemson, and Joe James, who operates Chestnut Return Farm in Oconee County.
Not exact matches
The attorney general's investigation was apparently spurred by a 2013 article in the New York Times that cited a University of Guelph
study that
used genetic analysis to examine various commercial herbal remedies.
Phase I funding — which allows up to $ 250,000 for an academic idea, such as decoding the
genetic sequence of a protein or
studying targeted drug delivery by
using magnetic nanoparticles — is available from federal funding and foundations.
This
study looked at
genetic (varieties) and management (row spacing and nitrogen) options to minimise the impact of climate change,
using rain - out shelters to control rainfall; the results provided a platform to model wheat production in future climates.
Please read how IVF medications led to my breast cancer and how a breast cancer
study using genetic testing to check estrogen metabolism is saving my life.
And a twin
study —
using the tools of behavioral genetics — found that
genetic factors had a negligible impact on the development of theory of mind skills (Hughes et al 2005).
Using studies of twins who had been separated at birth, yet displayed remarkably similar characteristics of personality despite differences in environment, Harris demonstrated the importance of
genetic predisposition as a factor in human development.
Many
studies show that once your child starts
using a drugs,
genetic factors may influence whether they develop an addiction.
Using a variety of plants, animals, and microbes, the researchers will
study the possibility that organisms can influence their own evolution and that inheritance can take place through routes other than the
genetic material.
In contrast, the new
study made
use of wrist accelerometer data, which is more objective and quantifiable, and a large
genetic dataset from about 85,000 UK Biobank participants aged 40 to 70.
So researchers have
used genetic studies to suggest that «a few lineages survived extinction and had a really fast radiation right afterwards,» says Daniel Ksepka, a paleo - ornithologist at the Bruce Museum in Greenwich, Connecticut, and the lead author on the paper.
The researchers
used two
genetic lines of mice in the
study to focus on AHR.
If there was one disadvantage to
using Ashkenazim in
genetic studies, it was that their blood relatives were harder to come by than in other groups.
The authors note that while the sample size of the meta - analyses was large (123,132 to 260,861 participants in different
studies), they
used only GWAS summary statistics and can not estimate all
genetic variance factors; some
studies also
used different methodologies.
The
study illustrates the versatility of SNAs, which are nontoxic to humans and can be
used, in principle, for any known
genetic target.
Since then, Pereira - Smith's team has moved into
using genetic techniques in mice to
study whether and how senescence is regulated by MORF4 and related genes.
Combing the
genetic data from a transmission
study in ferrets, a team led by Thomas Friedrich, a professor of pathobiological sciences at the University of Wisconsin - Madison School of Veterinary Medicine, found that during transmission, when one animal is infected by another through sneezing or coughing, the process of natural selection acts strongly on hemagglutinin, the structure the virus
uses to attach to and infect host cells.
Half of the patients treated in this
study responded to either ponatinib (typically
used for certain types of leukemia) or pazopinib (a kidney cancer drug), depending on the
genetic alterations identified through sequencing.
They are also
studying whether the nanoparticles can be
used with the CRISPR / Cas9 gene - editing technique to treat
genetic lesions related to retinal degenerative diseases.
Predisposition to vascular disease was my focus here,
using genetic epidemiological
studies to identify novel polymorphisms in a range of candidate genes.
Future
genetic studies of bone can
use this measure to learn about genes that are important to skeletal health.»
In this new
study published in Nature, Alexandra Van Keymeulen and colleagues
used state of the art
genetic mouse models to identify the cellular origin of PIK3CA and p53 induced breast tumors.
«It could allow some of the molecular and
genetic studies done on modern animals to be potentially
used on dinosaur samples.»
These results can also be
used by researchers
studying the
genetic underpinnings of mental disorders, as they indicate that the same genes might be associated with increased risk for various psychiatric disorders.»
In a new
study published in The Quarterly Review of Biology, Dr. Karen Hardy and her team bring together archaeological, anthropological,
genetic, physiological and anatomical data to argue that carbohydrate consumption, particularly in the form of starch, was critical for the accelerated expansion of the human brain over the last million years, and coevolved both with copy number variation of the salivary amylase genes and controlled fire
use for cooking.
We carried out detailed
genetic studies and
used whole genome sequencing to look at every part of the DNA at diagnosis, and every part of the DNA at relapse,» says Dr. Dick.
«
Genetic changes help mosquitoes survive pesticide attacks: Study shows how intensive pesticide use is driving mosquito evolution at the genetic level.
Genetic changes help mosquitoes survive pesticide attacks:
Study shows how intensive pesticide
use is driving mosquito evolution at the
genetic level.
genetic level.»
The
study, led by scientists from the University of Chicago,
uses a novel method to measure
genetic predisposition for telomere length, rather than physiological measures which are confounded by factors such as age and lifestyle.
While mouse models have traditionally been
used in
studying the
genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.
In a new
study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic, cells in Caenorhabditis elegans, a one - millimeter nematode commonly
used as a model for aging
studies in labs, activate
genetic pathways completely separate from those found in long - lived egg, or oocyte, cells.
«We
used different lines of evidence to show that ANGPTL3 deficiency is associated with a reduced risk of coronary artery disease,» said
study co-author Kiran Musunuru, MD, PhD, MPH, an associate professor of Cardiovascular Medicine at Penn. «But ultimately we were able to identify that fact that carriers of this
genetic mutation did in fact experience a benefit — with little other health risk.»
Two
study aims were to
use novel whole - genome sequence data to (1)
study possible correlations between language groups and
genetic clustering, and (2) investigate the ancestral compositions of these individuals, including maternal and paternal lineages.
And in a separate
study, researchers have already
used the sequence to chart a surprising degree of
genetic variation among women.
Results of each statistical test should be reported in full with the value of the test statistic and p - value, and not simply reported as significant or non-significant; more than two significant digits on p - values are usually not needed except in situations of extreme multiple testing such as in
genetic association
studies where stringent corrections for multiple testing might be
used.
The Duke
study is just one of many projects begun in the past five years that
use genetic sequencing to explore how the diversity of the microbiome impacts our health.
Here,
studying Brachypodium distachyon, a grass species related to major cereal grains like wheat, Michael Raissig et al.
used a
genetic screen to identify elements responsible for the unique morphology of grass stomata.
That's important if CRISPR / Cas9 will ever be
used to prevent
genetic diseases, says
study coauthor Shoukhrat Mitalipov, a reproductive and developmental biologist at Oregon Health & Science University in Portland.
Linkage
studies use genetic markers, which act like signposts, pointing researchers to the general area on the chromosome where genes associated with certain traits likely reside.
In addition to helping farmers check crop health, the new system will be helpful for
studying how plants respond to changes in growing conditions and for high - throughput phenotyping, an automated method
used in crop research and development to analyze how
genetic modifications affect plant characteristics such as leaf size or drought resistance in a large number of plants.
Both groups confirmed in
genetic, cell, and clinical
studies that, for the first time, the parasite had developed resistance to both drugs
used in an ACT.
In their
study, the team led by Stefanie Lutz and Liane G. Benning investigated the biodiversity of snow algae and other microbial communities
using high - throughput
genetic sequencing.
Ávila - Arcos hopes to
use genetic data to trace the ancestors of those in her
study back to specific West African groups or regions.
Instead of gathering and testing patients in person, as in traditional
studies, 23andMe researchers turned to online Parkinson's support groups to subscribe 3,426 patients, free of charge, to their service, which
uses a mailed - in spit sample to identify
genetic traits and disease risk factors.
The
study makes progress toward
using gene editing to prevent
genetic diseases, but there's still has a long way to go before clinical testing can begin, says Janet Rossant, a developmental biologist at the Hospital for Sick Children and the University of Toronto.
«It also remains to be elucidated whether this phenomenon is particular for the mouse strain
used in this
study or is a more general phenomenon that also occurs in other
genetic strains,» said Dr. Gerjo JVM van Osch, senior author of the Journal of Orthopedic Research article.
Scientists are bringing precision medicine to rheumatoid arthritis for the first time by
using genetic profiling of joint tissue to see which drugs will work for which patients, reports a new Northwestern Medicine multi-site
study.
Using a novel combination of technologies, including trio exome sequencing of patient / parental DNA and
genetic studies in the tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found that mutations in the gene CHD2 are responsible for a subset of epilepsy patients with symptoms similar to Dravet syndrome — a severe form of childhood epilepsy that is in many patients resistant to currently available anti-epileptic drugs.
Those
studies, which
used less precise
genetic tests, showed differences between females at beaches thousands of miles apart but provided no data on males.
The team of researchers was the first in the world to
use modern
genetic, molecular and biochemical methods to
study tooth enamel defects in detail.